Shenzhi Chen
shenzhichen1999.bsky.social
Shenzhi Chen
@shenzhichen1999.bsky.social
PhD student in Stark group@IMP Vienna, Machine Learning, Gene Regulation
Pinned
Excited to share our paper in @natgenet.nature.com on the de novo design of tissue-specific mammalian enhancers that function in vivo in mouse embryos. 🧬🐭
www.nature.com/articles/s41...
Excited to share our paper in @natgenet.nature.com on the de novo design of tissue-specific mammalian enhancers that function in vivo in mouse embryos. 🧬🐭
www.nature.com/articles/s41...
August 25, 2026 at 9:18 AM
🚀 Excited to share our latest work now on bioRxiv: the computational de novo design of tissue‑specific mammalian enhancers that work in vivo in the mouse embryo. 🐭

More details in the preprint and code:
bioRxiv: biorxiv.org/content/10.6...
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Predictive design of tissue-specific mammalian enhancers that function in vivo in the mouse embryo
Enhancers control tissue-specific gene expression across metazoans. Although deep learning has enabled enhancer prediction and design in mammalian cell lines and invertebrate systems, it remains uncle...
biorxiv.org
December 24, 2025 at 5:46 PM