The IMP lab of Alexander Stark used AI to design enhancers—DNA switches controlling gene activity—for specific mouse tissues: the first from-scratch design in a mammal.
News: imp.ac.at/news/article/ai-learns-to-write-code-that-activates-genes-in-mammals
Paper: nature.com/articles/s41588-026-02729-1

First synthetic mouse enhancers active in defined embryonic tissues! Great collaboration led by @alex-stark.bsky.social lab now at @natgenet.nature.com

Excited to share our paper in @natgenet.nature.com on the de novo design of tissue-specific mammalian enhancers that function in vivo in mouse embryos. 🧬🐭
www.nature.com/articles/s41...