Vladimir Mindel
@vmindel.bsky.social
PhD student, Weizmann Institute of Science. Interested in all things chromatin.
New paper out in Genome Research! 🧬 We show how disordered N-terminal domains of Steroid Receptors shape their DNA-binding specificity.
Using ChEC-seq, we mapped TF binding at base-pair resolution and combined it with mutagenesis of the disordered domains.
genome.cshlp.org/content/earl...
Using ChEC-seq, we mapped TF binding at base-pair resolution and combined it with mutagenesis of the disordered domains.
genome.cshlp.org/content/earl...
genome.cshlp.org
July 1, 2026 at 10:32 AM
New paper out in Genome Research! 🧬 We show how disordered N-terminal domains of Steroid Receptors shape their DNA-binding specificity.
Using ChEC-seq, we mapped TF binding at base-pair resolution and combined it with mutagenesis of the disordered domains.
genome.cshlp.org/content/earl...
Using ChEC-seq, we mapped TF binding at base-pair resolution and combined it with mutagenesis of the disordered domains.
genome.cshlp.org/content/earl...
Reposted by Vladimir Mindel
Hot from the press!🔥
Excited to share our recent Perspective on the role of intrinsically disordered regions of eukaryotic transcription factors in the target search process 🔎:
www.nature.com/articles/s41... 😱
Excited to share our recent Perspective on the role of intrinsically disordered regions of eukaryotic transcription factors in the target search process 🔎:
www.nature.com/articles/s41... 😱
Intrinsically disordered regions as facilitators of the transcription factor target search - Nature Reviews Genetics
Intrinsically disordered domains (IDRs) are increasingly appreciated as important components of protein function. This Perspective discusses the emerging evidence for IDRs from transcription factors a...
www.nature.com
February 21, 2025 at 1:21 PM
Hot from the press!🔥
Excited to share our recent Perspective on the role of intrinsically disordered regions of eukaryotic transcription factors in the target search process 🔎:
www.nature.com/articles/s41... 😱
Excited to share our recent Perspective on the role of intrinsically disordered regions of eukaryotic transcription factors in the target search process 🔎:
www.nature.com/articles/s41... 😱
Reposted by Vladimir Mindel
New seminar series! Join us to explore how protein structures evolved!
Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫
ProSE launches one day before Darwin's day!
📅 Feb 11, 3PM GMT
🔗https://tinyurl.com/prose-seminar1
Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫
ProSE launches one day before Darwin's day!
📅 Feb 11, 3PM GMT
🔗https://tinyurl.com/prose-seminar1
February 3, 2025 at 5:01 PM
New seminar series! Join us to explore how protein structures evolved!
Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫
ProSE launches one day before Darwin's day!
📅 Feb 11, 3PM GMT
🔗https://tinyurl.com/prose-seminar1
Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫
ProSE launches one day before Darwin's day!
📅 Feb 11, 3PM GMT
🔗https://tinyurl.com/prose-seminar1