Wouter Moolenaar
@wouterhm.bsky.social
Biomedical scientist, cancer research, cell biology, lipid mediators. Music lover, piano.
First there was the mysterious dark matter in the universe, now there are mysterious dark proteins inside our cells. Exciting times ahead!
The code for these proteins was excluded from official genome and protein counts
go.nature.com/4tkbGOH
go.nature.com/4tkbGOH
Revealed: the mysterious ‘dark’ proteins that might play a big role in biology
Nature - Thousands of ‘dark proteins’ have been reclassified as peptideins and added to databases as a new category.
go.nature.com
May 10, 2026 at 1:24 PM
First there was the mysterious dark matter in the universe, now there are mysterious dark proteins inside our cells. Exciting times ahead!
Reposted by Wouter Moolenaar
Derek once again equivocating on anti-amyloid antibodies as an Alzheimer's therapy:
"I do not see why these antibodies should be on the market."
"Do something else! For God's sake, do something else."
www.science.org/content/blog...
"I do not see why these antibodies should be on the market."
"Do something else! For God's sake, do something else."
www.science.org/content/blog...
Science | AAAS
www.science.org
April 17, 2026 at 5:47 PM
Derek once again equivocating on anti-amyloid antibodies as an Alzheimer's therapy:
"I do not see why these antibodies should be on the market."
"Do something else! For God's sake, do something else."
www.science.org/content/blog...
"I do not see why these antibodies should be on the market."
"Do something else! For God's sake, do something else."
www.science.org/content/blog...
Four decades after their discovery, lipid-anchored proteins still hold mysteries. Our Opinion article sheds light on how these proteins are released from their anchors, and how this process rewires signaling networks and impacts cell fate: Trends in Cell Biology www.cell.com/trends/cell-...
Unlocking the signaling potential of GPI-anchored proteins through lipolytic cleavage
Glycosylphosphatidylinositol (GPI)-anchored proteins (APs) regulate numerous biological
processes through interaction with signaling effectors at the cell surface. As a unique
feature, GPI-APs can be ...
www.cell.com
January 25, 2025 at 4:41 PM
Four decades after their discovery, lipid-anchored proteins still hold mysteries. Our Opinion article sheds light on how these proteins are released from their anchors, and how this process rewires signaling networks and impacts cell fate: Trends in Cell Biology www.cell.com/trends/cell-...