Yehor Tertyshnyk
@yehor-tk.bsky.social
Reposted by Yehor Tertyshnyk
Is euchromatin really “open”? 🧬 Using super-resolution imaging🔬 our new study @natgenet.nature.com reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing for proper transcriptional insulation🚧 🔗
www.nature.com/articles/s41... (1/2)
www.nature.com/articles/s41... (1/2)
September 8, 2026 at 10:22 AM
Is euchromatin really “open”? 🧬 Using super-resolution imaging🔬 our new study @natgenet.nature.com reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing for proper transcriptional insulation🚧 🔗
www.nature.com/articles/s41... (1/2)
www.nature.com/articles/s41... (1/2)
Reposted by Yehor Tertyshnyk
New paper with @jacobmusser.bsky.social @dts.bsky.social on reproducibility of LLM assisted research. Much of what we learned about engineering reproducible work in past decades still applies. Central organizing principle is whether the LLM sits on data path or off it. www.cell.com/patterns/ful...
September 8, 2026 at 12:51 PM
New paper with @jacobmusser.bsky.social @dts.bsky.social on reproducibility of LLM assisted research. Much of what we learned about engineering reproducible work in past decades still applies. Central organizing principle is whether the LLM sits on data path or off it. www.cell.com/patterns/ful...
Reposted by Yehor Tertyshnyk
Our new paper in Science Advances asks how animals' genomes have changed since their origin from a common ancestor over 600 million years ago, and what patterns in their DNA have arisen in the churn of speciation and extinction. www.science.org/doi/10.1126/...
August 19, 2026 at 6:45 PM
Our new paper in Science Advances asks how animals' genomes have changed since their origin from a common ancestor over 600 million years ago, and what patterns in their DNA have arisen in the churn of speciation and extinction. www.science.org/doi/10.1126/...
Reposted by Yehor Tertyshnyk
We know little about proteins required for long-range compartment 3D interactions, but this @kyleeagen.bsky.social lab preprint shows that NSD3 can make Mb-scale long-range compartment-like interactions:
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
July 25, 2026 at 9:23 PM
We know little about proteins required for long-range compartment 3D interactions, but this @kyleeagen.bsky.social lab preprint shows that NSD3 can make Mb-scale long-range compartment-like interactions:
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Yehor Tertyshnyk
Annual killifish continue to surprise us: they make neutrophils before almost every other cell type, even before gastrulation. Neutrophils usually arise from the lateral plate mesoderm (forming in cyan), but in killifish they are already patrolling around the embryo in gold. tinyurl.com/killiphil
June 30, 2026 at 4:11 PM
Annual killifish continue to surprise us: they make neutrophils before almost every other cell type, even before gastrulation. Neutrophils usually arise from the lateral plate mesoderm (forming in cyan), but in killifish they are already patrolling around the embryo in gold. tinyurl.com/killiphil
Reposted by Yehor Tertyshnyk
(1/n) Very excited to share tri-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack:
Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)?
A: Transient E-P contact (~25-42 nm lasting ~10-20 sec):
www.biorxiv.org/content/10.6...
Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)?
A: Transient E-P contact (~25-42 nm lasting ~10-20 sec):
www.biorxiv.org/content/10.6...
June 22, 2026 at 3:32 PM
(1/n) Very excited to share tri-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack:
Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)?
A: Transient E-P contact (~25-42 nm lasting ~10-20 sec):
www.biorxiv.org/content/10.6...
Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)?
A: Transient E-P contact (~25-42 nm lasting ~10-20 sec):
www.biorxiv.org/content/10.6...