Ying Wang
@yingwangyw.bsky.social
Instructor in Medicine & former postdoc @MGH/HMS | Broad Institute
Reposted by Ying Wang
🧬 New preprint! We present an All by All analysis in All of Us: common and rare variant association testing across 392,030 whole genomes and 3,602 phenotypes. 1.337 trillion tests, ~50k significant signals, all publicly browseable. www.medrxiv.org/content/10.6...
Systematic common and rare variant association testing in 392,030 whole genomes in All of Us
Large-scale genome-wide association studies (GWAS) and rare variant association studies (RVAS) from population biobanks provide valuable resources for gene discovery in complex human traits. We presen...
www.medrxiv.org
May 13, 2026 at 1:10 PM
🧬 New preprint! We present an All by All analysis in All of Us: common and rare variant association testing across 392,030 whole genomes and 3,602 phenotypes. 1.337 trillion tests, ~50k significant signals, all publicly browseable. www.medrxiv.org/content/10.6...
🎉New preprint: Phenome-derived polygenic scores and social determinants jointly shape context-dependent disease risk.
We evaluate disease risk along 2 complementary axes:
• how genetic liability is represented
• the social context in which it is expressed
We evaluate disease risk along 2 complementary axes:
• how genetic liability is represented
• the social context in which it is expressed
April 23, 2026 at 5:22 PM
🎉New preprint: Phenome-derived polygenic scores and social determinants jointly shape context-dependent disease risk.
We evaluate disease risk along 2 complementary axes:
• how genetic liability is represented
• the social context in which it is expressed
We evaluate disease risk along 2 complementary axes:
• how genetic liability is represented
• the social context in which it is expressed