Some subjective impressions of trends from #eseb2025.
Genomic inbreeding through F_ROH has made it big. As it should.
Genomic prediction hasn't. Perhaps single step would help bridge the gap between pedigree and genotype datasets.
Selection mapping has calmed down, but I still saw some Fst scans.
Genomic inbreeding through F_ROH has made it big. As it should.
Genomic prediction hasn't. Perhaps single step would help bridge the gap between pedigree and genotype datasets.
Selection mapping has calmed down, but I still saw some Fst scans.
August 23, 2025 at 12:01 PM
Some subjective impressions of trends from #eseb2025.
Genomic inbreeding through F_ROH has made it big. As it should.
Genomic prediction hasn't. Perhaps single step would help bridge the gap between pedigree and genotype datasets.
Selection mapping has calmed down, but I still saw some Fst scans.
Genomic inbreeding through F_ROH has made it big. As it should.
Genomic prediction hasn't. Perhaps single step would help bridge the gap between pedigree and genotype datasets.
Selection mapping has calmed down, but I still saw some Fst scans.
@btschirren.bsky.social The badger project looks super exciting and ambitious! I teach about the genetics of bovine TB and cattle breeding each spring; looking forward to add the badger side of the story in a few years then. :) #eseb2025
August 21, 2025 at 4:43 PM
@btschirren.bsky.social The badger project looks super exciting and ambitious! I teach about the genetics of bovine TB and cattle breeding each spring; looking forward to add the badger side of the story in a few years then. :) #eseb2025
Karolina Wąchała is building one of the things selection scans _really_ need: workflows for simulation so that one can check "whether you could even detect selection in your study". #eseb2025
August 21, 2025 at 1:59 PM
Karolina Wąchała is building one of the things selection scans _really_ need: workflows for simulation so that one can check "whether you could even detect selection in your study". #eseb2025
Indeed. :) I saw one example of what I think was deep learning: segmentation of images of cichlids from Wouter van der Bijl, followed by more parametric computer vision analyses. Funnily enough, we've done similar things as our only deep learning application. U-Net is really useful. #eseb2025
August 21, 2025 at 10:44 AM
Indeed. :) I saw one example of what I think was deep learning: segmentation of images of cichlids from Wouter van der Bijl, followed by more parametric computer vision analyses. Funnily enough, we've done similar things as our only deep learning application. U-Net is really useful. #eseb2025
Pierre de Villemereuil: Partitioning the phenotypic and genetic variances of reaction norms
#eseb2025
peercommunityjournal.org/item/10_2407...
#eseb2025
peercommunityjournal.org/item/10_2407...
Partitioning the phenotypic and genetic variances of reaction norms
peercommunityjournal.org
August 21, 2025 at 9:03 AM
Pierre de Villemereuil: Partitioning the phenotypic and genetic variances of reaction norms
#eseb2025
peercommunityjournal.org/item/10_2407...
#eseb2025
peercommunityjournal.org/item/10_2407...
Lou Guyot: Long term balancing selection can favour the evolution of recombination suppression by linked selection on deleterious recessive alleles. www.biorxiv.org/content/10.1...
(From the posters. A preprint QR code is really the best part of a poster.)
#eseb2025
(From the posters. A preprint QR code is really the best part of a poster.)
#eseb2025
Loci under balancing selection facilitate the emergence of pseudo-overdominance and recombination suppression
Loci under strong balancing selection, such as sex-determining, mating-type, and self-incompatibility loci, are frequently flanked by regions of suppressed recombination. The reasons why recombination...
www.biorxiv.org
August 21, 2025 at 8:02 AM
Lou Guyot: Long term balancing selection can favour the evolution of recombination suppression by linked selection on deleterious recessive alleles. www.biorxiv.org/content/10.1...
(From the posters. A preprint QR code is really the best part of a poster.)
#eseb2025
(From the posters. A preprint QR code is really the best part of a poster.)
#eseb2025
Charissa de Bekker showing a lot of molecular and behavioural work to figure out what a previously unknown, highly differentially expressed, fungal candidate effector ptotein is doing--finding the protein it interacts with, experimentally testing effects on behaviour. #eseb2025
August 21, 2025 at 7:32 AM
Charissa de Bekker showing a lot of molecular and behavioural work to figure out what a previously unknown, highly differentially expressed, fungal candidate effector ptotein is doing--finding the protein it interacts with, experimentally testing effects on behaviour. #eseb2025
Charissa de Bekker: "... of course, Ophiocordyceps has its own parasites, so there are fungi that parasitize the fungus." #eseb2025 #BiologyBeingBiology
August 21, 2025 at 7:29 AM
Charissa de Bekker: "... of course, Ophiocordyceps has its own parasites, so there are fungi that parasitize the fungus." #eseb2025 #BiologyBeingBiology
Malvika Srivastava showed a model that has a space for stable polymorphism maintained by queen--worker conflict in eusocial insects when there is dominance reversal. #eseb2025
August 20, 2025 at 6:50 PM
Malvika Srivastava showed a model that has a space for stable polymorphism maintained by queen--worker conflict in eusocial insects when there is dominance reversal. #eseb2025
Craig Primmer told the, story of a major locus probably maintained by several mechanisms, the spiciest arguably being sex specific overdominance. (Also, a super ambitious longitudinal dataset.) #eseb2025
August 20, 2025 at 6:40 PM
Craig Primmer told the, story of a major locus probably maintained by several mechanisms, the spiciest arguably being sex specific overdominance. (Also, a super ambitious longitudinal dataset.) #eseb2025
Rus Hoelzel showed an intriguing example of long term balancing selection on many loci, potentially because of ecotype specialisation between deep and shallow water, with spawning and juvenile stage at intermediate depth. #eseb2025
August 20, 2025 at 6:37 PM
Rus Hoelzel showed an intriguing example of long term balancing selection on many loci, potentially because of ecotype specialisation between deep and shallow water, with spawning and juvenile stage at intermediate depth. #eseb2025
I took a break from live posting today, but the session on maintenance of polymorphism was delightful. Some highlights: Karl Grieshop questioned the notion of "maintenance" overall. Erik Svensson showed a cool example of a clade with lots of female-limited stable polymorphism. #eseb2025
August 20, 2025 at 6:27 PM
I took a break from live posting today, but the session on maintenance of polymorphism was delightful. Some highlights: Karl Grieshop questioned the notion of "maintenance" overall. Erik Svensson showed a cool example of a clade with lots of female-limited stable polymorphism. #eseb2025
Ravi Vishwakarma on modelling of genetic diversity under range expansion and contraction.
pubmed.ncbi.nlm.nih.gov/39663680/
#eseb2025
pubmed.ncbi.nlm.nih.gov/39663680/
#eseb2025
Species-Specific Traits Shape Genetic Diversity During an Expansion-Contraction Cycle and Bias Demographic History Reconstruction - PubMed
Species ranges are dynamic, experiencing expansions, contractions or shifts in response to habitat changes driven by extrinsic factors such as climate change or human activities. While existing resear...
pubmed.ncbi.nlm.nih.gov
August 19, 2025 at 1:42 PM
Ravi Vishwakarma on modelling of genetic diversity under range expansion and contraction.
pubmed.ncbi.nlm.nih.gov/39663680/
#eseb2025
pubmed.ncbi.nlm.nih.gov/39663680/
#eseb2025
Jana Nickel: little evidence of deleterious variants hitchhiking on freshwater adaptation in stickleback.
www.biorxiv.org/content/10.1...
#eseb2025
www.biorxiv.org/content/10.1...
#eseb2025
Complex patterns of hitchhiking mutation load among stickleback populations
Positive selection causes beneficial alleles to rapidly rise to high frequency in a population. This can cause linked genetic variation to " hitchhike " , and thereby also rise in frequency. This link...
www.biorxiv.org
August 19, 2025 at 1:30 PM
Jana Nickel: little evidence of deleterious variants hitchhiking on freshwater adaptation in stickleback.
www.biorxiv.org/content/10.1...
#eseb2025
www.biorxiv.org/content/10.1...
#eseb2025
Holly Nelson on genomic studies of a critically endangered turtle.
There was "barely any diversity in this species", a genome 90% covered by runs of homozygosity--but she found one region that was not covered, and identified the turtle MHC.
#eseb2025
pubmed.ncbi.nlm.nih.gov/40327086/
There was "barely any diversity in this species", a genome 90% covered by runs of homozygosity--but she found one region that was not covered, and identified the turtle MHC.
#eseb2025
pubmed.ncbi.nlm.nih.gov/40327086/
Genome-wide diversity and MHC characterisation in a critically endangered freshwater turtle susceptible to disease - PubMed
Small, isolated populations are often vulnerable to increased inbreeding and genetic drift, both of which elevate the risk of extinction. The Bellinger River turtle (Myuchelys georgesi) is a criticall...
pubmed.ncbi.nlm.nih.gov
August 19, 2025 at 10:44 AM
Holly Nelson on genomic studies of a critically endangered turtle.
There was "barely any diversity in this species", a genome 90% covered by runs of homozygosity--but she found one region that was not covered, and identified the turtle MHC.
#eseb2025
pubmed.ncbi.nlm.nih.gov/40327086/
There was "barely any diversity in this species", a genome 90% covered by runs of homozygosity--but she found one region that was not covered, and identified the turtle MHC.
#eseb2025
pubmed.ncbi.nlm.nih.gov/40327086/
Neelam Porwal presenting a sexual selection experiment with fighting soil mites, where populations with high proportion of fighter males dealt better with heat stress. #eseb2025
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Fighting Through the Heat: How Sexual Selection Influences Demography Under Recurrent Heatwaves
Sexual selection is a potent evolutionary force with complex effects. Strong sexual selection can enhance adaptation and reduce mutational load, while simultaneously reducing survival, or causing sexu...
www.biorxiv.org
August 19, 2025 at 10:31 AM
Neelam Porwal presenting a sexual selection experiment with fighting soil mites, where populations with high proportion of fighter males dealt better with heat stress. #eseb2025
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
This is the session for me, clearly. Population genetic simulation, F_ROH, museum sample sequencing, open field behaviour testing and heat stress. #eseb2025
August 19, 2025 at 9:49 AM
This is the session for me, clearly. Population genetic simulation, F_ROH, museum sample sequencing, open field behaviour testing and heat stress. #eseb2025
Hernán Morales kicks off the small populations session with a series of birds that have gone through demographic collapse, using sequencing of museum samples to establish what the variation was like before the decline, and simulation to understand the implications of the data.
#eseb2025
#eseb2025
August 19, 2025 at 9:26 AM
Hernán Morales kicks off the small populations session with a series of birds that have gone through demographic collapse, using sequencing of museum samples to establish what the variation was like before the decline, and simulation to understand the implications of the data.
#eseb2025
#eseb2025
Dieter Ebert: trans-species polymorphism in resistance loci in Daphnia, i.e., resistance alleles are really quite old and have had time to accumulate structural complexity.
www.nature.com/articles/s41...
academic.oup.com/gbe/article/...
#eseb2025
www.nature.com/articles/s41...
academic.oup.com/gbe/article/...
#eseb2025
Long-term balancing selection for pathogen resistance maintains trans-species polymorphisms in a planktonic crustacean - Nature Communications
Trans-species polymorphisms (TSP) in disease loci are thought to be caused by long-term host-parasite coevolution. Here, the authors identify consistent TSPs across three species of Daphnia and find s...
www.nature.com
August 19, 2025 at 8:23 AM
Dieter Ebert: trans-species polymorphism in resistance loci in Daphnia, i.e., resistance alleles are really quite old and have had time to accumulate structural complexity.
www.nature.com/articles/s41...
academic.oup.com/gbe/article/...
#eseb2025
www.nature.com/articles/s41...
academic.oup.com/gbe/article/...
#eseb2025
Beatriz Vicoso: Artemia brine shrimp have complete dosage compensation of their Z chromosome. She proposes that they're using a system similar to MSL for Drosophila X. Cool contrast to e.g. birds, whose ZW are doing something different entirely. academic.oup.com/mbe/article/...
#eseb2025
#eseb2025
Chromatin Landscape Is Associated With Sex-Biased Expression and Drosophila-Like Dosage Compensation of the Z Chromosome in Artemia franciscana
Abstract. The males and females of the brine shrimp Artemia franciscana are highly dimorphic, and this dimorphism is associated with substantial sex-biased
academic.oup.com
August 19, 2025 at 7:28 AM
Beatriz Vicoso: Artemia brine shrimp have complete dosage compensation of their Z chromosome. She proposes that they're using a system similar to MSL for Drosophila X. Cool contrast to e.g. birds, whose ZW are doing something different entirely. academic.oup.com/mbe/article/...
#eseb2025
#eseb2025
Every time I go to ESEB, I'm struck by the elegance of plant evolutionary genetics. This time, it was Elizabeth Davies' talk on allopolyploidy in British eyebrights. #eseb2025
August 18, 2025 at 1:23 PM
Every time I go to ESEB, I'm struck by the elegance of plant evolutionary genetics. This time, it was Elizabeth Davies' talk on allopolyploidy in British eyebrights. #eseb2025