Rahul Raina et al.: Cryo-EM structures of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase in the apo state and in the presence of small molecules ##CryoEM##Tuberculosis##HistidineBiosynthesisPathway... ##IUCrhttps://journals.iucr.org/paper?S2053230X25004595

This study of imidazole glycerol phosphate dehydratase suggests that cryo-EM can be useful in pinpointing the mode of binding small molecules of low mass and mapping protein-ligand interactions #CryoEM #Tuberculosis #HistidineBiosynthesisPathway doi.org/10.1107/S205...

Cryo-EM structures of M. tuberculosis imidazole glycerol phosphate dehydratase suggest that the enzyme exhibits a 24-mer assembly with 432 symmetry in both apo and small-molecule-bound states.

➡️ https://ow.ly/ljL150YntpN
Structural Biology Communications #Tuberculosis #HistidineBiosynthesisPathway