#µPAC
My last Thermo leak for ASMS 2025? The Optispray source.
- Integrated cartridge combines column, liquid junction, and replaceable emitter
- 5 cartridge: PepMap Neo 15cm/50cm, µPAC Neo 50cm & HT, and no column
- For nano and capillary flow LC-MS
- Auto-aligns in ~3 mins (quick) and ~20 mins (full)
May 6, 2025 at 11:25 AM
A full room at yesterday's Thermo Fisher Scientific User Meeting at the start of the ESCP25 Conference. Special highlight to me was the presented performance and longevity of the new #µPAC Neo Plus columns for single-cell Proteomics applications.
August 26, 2025 at 6:47 AM
I just want to highlight the new µPAC Neo Plus columns for bottom-up proteomics. Especially with scProteomics in mind, with where protein amounts are easily less than 100pg.
In this poster, 2000 protein groups were identified from a single digested Hela cell.
assets.thermofisher.com/TFS-Assets/C...
August 15, 2025 at 1:46 PM
Just following from last week, with the first Paper showcasing the µPAC Neo Plus column in single-cell Proteomics., by Jakob Woessmann and Erwin Schoof.
For a peek at their methods, please visit www.biorxiv.org/content/10.1...
Informed Data-Independent Acquisition Enables Targeted Quantification of Key Regulatory Proteins in Cell Fate Decision at Single-Cell Resolution
Cellular differentiation processes are largely orchestrated by variation in transcription factor (TF) abundance. Since these proteins are usually expressed at extremely low levels, studying TF-driven ...
www.biorxiv.org
August 22, 2025 at 3:04 PM