July 19, 2025 at 5:27 PM
Amazing structures, and distinct binding modes, of TOPBP1 or ETAA1 activating the ATR-ATRIP kinase by an allosteric mechanism. In NSMB from Pavletich lab: www.nature.com/articles/s41...
Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase - Nature Structural & Molecular Biology
Li et al. present cryo-EM structures of the ATR–ATRIP complex bound to the ATR-activating domains of TOPBP1 and ETAA1; these reveal distinct binding modes and allosteric mechanism of activation for TO...
www.nature.com
August 4, 2026 at 11:16 PM
Amazing structures, and distinct binding modes, of TOPBP1 or ETAA1 activating the ATR-ATRIP kinase by an allosteric mechanism. In NSMB from Pavletich lab: www.nature.com/articles/s41...
“Langur” by ATRIP #nowplaying #radio1
September 29, 2026 at 6:35 PM
“Langur” by ATRIP #nowplaying #radio1
🎵 ATRIP - pull u right thru 🎧 picked by Chris
ATRIP - pull u right thru
Listen to this h0t track on youtube
www.youtube.com
September 30, 2026 at 3:26 AM
🎵 ATRIP - pull u right thru 🎧 picked by Chris
ATRIP - pull u right thru ... soundcloud.com/itsatrip/pul...
September 30, 2026 at 3:05 PM
ATRIP - pull u right thru ... soundcloud.com/itsatrip/pul...
BBC Radio 1
Radio 1's New Music Show with Jack Saunders
Now Playing
ATRIP
Langur
Radio 1's New Music Show with Jack Saunders
Now Playing
ATRIP
Langur
September 29, 2026 at 6:35 PM
BBC Radio 1
Radio 1's New Music Show with Jack Saunders
Now Playing
ATRIP
Langur
Radio 1's New Music Show with Jack Saunders
Now Playing
ATRIP
Langur
New online: Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR–ATRIP
Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR–ATRIP
Nature Structural & Molecular Biology, Published online: 17 September 2026; doi:10.1038/s41594-026-01887-4Wang et al. present cryo-electron microscopy structures of ATR–ATRIP complexes in distinct functional states, revealing ATP-dependent and TopBP1-dependent mechanisms of kinase activation and how ATR inhibitors exploit ATP-binding pocket flexibility for selective inhibition.
dlvr.it
September 17, 2026 at 10:09 AM
New online: Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR–ATRIP
New online: Capturing ATR–ATRIP in the act of activation
Capturing ATR–ATRIP in the act of activation
Nature Structural & Molecular Biology, Published online: 17 September 2026; doi:10.1038/s41594-026-01899-0The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP activation, capturing distinct active states of the kinase and clarifying how its activity is stimulated by TOPBP1 and ETAA1.
dlvr.it
September 17, 2026 at 10:09 AM
New online: Capturing ATR–ATRIP in the act of activation
Thundercat popped out at Erykah Badu's album listening party and gave a surprise rendition of 'Them Changes'.
His feature on her new album is included in this week's On Repeat Playlist update. Alongside other tracks from Shy Girl, Atrip & more
Link: ninjatune.lnk.to/onrepeat
Vid: Justin Mandel
His feature on her new album is included in this week's On Repeat Playlist update. Alongside other tracks from Shy Girl, Atrip & more
Link: ninjatune.lnk.to/onrepeat
Vid: Justin Mandel
September 14, 2026 at 5:27 PM
Thundercat popped out at Erykah Badu's album listening party and gave a surprise rendition of 'Them Changes'.
His feature on her new album is included in this week's On Repeat Playlist update. Alongside other tracks from Shy Girl, Atrip & more
Link: ninjatune.lnk.to/onrepeat
Vid: Justin Mandel
His feature on her new album is included in this week's On Repeat Playlist update. Alongside other tracks from Shy Girl, Atrip & more
Link: ninjatune.lnk.to/onrepeat
Vid: Justin Mandel
Sinai Ray by ATRIP 🎧
link.deezer.com/s/31A9eQgnz0...
link.deezer.com/s/31A9eQgnz0...
Sinai Ray
ATRIP - song - 2025
link.deezer.com
November 12, 2025 at 7:52 AM
Sinai Ray by ATRIP 🎧
link.deezer.com/s/31A9eQgnz0...
link.deezer.com/s/31A9eQgnz0...
Read the story of the beautiful young Canadian police officer. She was subject to ATRIP SEARCHES and incarcerated for exactly ZERO.
No way me or mine would be coming back there.
I guess 7 trips to Florida is enough.
That's a whole lot of homes not getting rented and hence defaulted on.
No way me or mine would be coming back there.
I guess 7 trips to Florida is enough.
That's a whole lot of homes not getting rented and hence defaulted on.
July 19, 2025 at 6:34 AM
Read the story of the beautiful young Canadian police officer. She was subject to ATRIP SEARCHES and incarcerated for exactly ZERO.
No way me or mine would be coming back there.
I guess 7 trips to Florida is enough.
That's a whole lot of homes not getting rented and hence defaulted on.
No way me or mine would be coming back there.
I guess 7 trips to Florida is enough.
That's a whole lot of homes not getting rented and hence defaulted on.
Every single evening 7 news begins their bulletin with Melbourne crime, regardless of whatever else is happening.
At least the ABC doesn't do that.
Nevertheless as a country person when I have atrip to Melb people ask me did I feel safe...
Er, yes, no different to any other city.
At least the ABC doesn't do that.
Nevertheless as a country person when I have atrip to Melb people ask me did I feel safe...
Er, yes, no different to any other city.
December 6, 2025 at 11:22 AM
Every single evening 7 news begins their bulletin with Melbourne crime, regardless of whatever else is happening.
At least the ABC doesn't do that.
Nevertheless as a country person when I have atrip to Melb people ask me did I feel safe...
Er, yes, no different to any other city.
At least the ABC doesn't do that.
Nevertheless as a country person when I have atrip to Melb people ask me did I feel safe...
Er, yes, no different to any other city.
ICYMI: New online: Capturing ATR–ATRIP in the act of activation
Capturing ATR–ATRIP in the act of activation
Nature Structural & Molecular Biology, Published online: 17 September 2026; doi:10.1038/s41594-026-01899-0The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP activation, capturing distinct active states of the kinase and clarifying how its activity is stimulated by TOPBP1 and ETAA1.
dlvr.it
September 18, 2026 at 10:10 AM
ICYMI: New online: Capturing ATR–ATRIP in the act of activation
ICYMI: New online: Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase
Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase
Nature Structural & Molecular Biology, Published online: 23 July 2026; doi:10.1038/s41594-026-01844-1Li et al. present cryo-EM structures of the ATR–ATRIP complex bound to the ATR-activating domains of TOPBP1 and ETAA1; these reveal distinct binding modes and allosteric mechanism of activation for TOPBP1 and ETAA1.
dlvr.it
July 24, 2026 at 9:27 AM
ICYMI: New online: Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase
I'm wearing my leopard print trousers because they're wide leg and I'm hoping I don't have to atrip and stand shivering and knock knees in my pants in front of the physio, that's bound to be either a fit bloke or an impossibly tiny woman. Can just roll my trouser leg up, yeah?
March 6, 2025 at 9:01 AM
I'm wearing my leopard print trousers because they're wide leg and I'm hoping I don't have to atrip and stand shivering and knock knees in my pants in front of the physio, that's bound to be either a fit bloke or an impossibly tiny woman. Can just roll my trouser leg up, yeah?
The not so easy job of protecting our DNA: a publication in @natsmb.nature.com from the lab of Nikola Pavletich at @mskcancercenter.bsky.social in which researchers describe the structure of ATR-ATRIP complex bound to its two activators.
Read more here: buff.ly/S5IWOVw
#SBGrid #DNARepair
Read more here: buff.ly/S5IWOVw
#SBGrid #DNARepair
The not so easy job of protecting our DNA
SBGrid member Nikola Pavletich reports on the structure of ATR-ATRIP complex bound to two activators, revealing key DNA-damage checkpoints.
medium.com
September 10, 2026 at 4:05 PM
The not so easy job of protecting our DNA: a publication in @natsmb.nature.com from the lab of Nikola Pavletich at @mskcancercenter.bsky.social in which researchers describe the structure of ATR-ATRIP complex bound to its two activators.
Read more here: buff.ly/S5IWOVw
#SBGrid #DNARepair
Read more here: buff.ly/S5IWOVw
#SBGrid #DNARepair
ICYMI: New online: Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR–ATRIP
Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR–ATRIP
Nature Structural & Molecular Biology, Published online: 17 September 2026; doi:10.1038/s41594-026-01887-4Wang et al. present cryo-electron microscopy structures of ATR–ATRIP complexes in distinct functional states, revealing ATP-dependent and TopBP1-dependent mechanisms of kinase activation and how ATR inhibitors exploit ATP-binding pocket flexibility for selective inhibition.
dlvr.it
September 18, 2026 at 10:10 AM
ICYMI: New online: Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR–ATRIP
Structural mechanism of TOPBP1 activating the ATR-ATRIP replication checkpoint kinase pubmed.ncbi.nlm.nih.gov/42493622/ #cryoem
July 24, 2026 at 10:42 AM
Structural mechanism of TOPBP1 activating the ATR-ATRIP replication checkpoint kinase pubmed.ncbi.nlm.nih.gov/42493622/ #cryoem
We keep rocking the #AOTYCountdown!
3422. Subskile
3421. The MARX
3420. wav-dr.
3419. The Peace Lilies
3418. So Called Chris
3417. Onika Venus
3416. Irish Handcuffs
3415. Art of Chaos
3414. Atrip
3413. Olabayo
3412. Thieves Of Liberty
3411. The Voublys
3410. Janine Fourie
3409. Chris Spruit
3422. Subskile
3421. The MARX
3420. wav-dr.
3419. The Peace Lilies
3418. So Called Chris
3417. Onika Venus
3416. Irish Handcuffs
3415. Art of Chaos
3414. Atrip
3413. Olabayo
3412. Thieves Of Liberty
3411. The Voublys
3410. Janine Fourie
3409. Chris Spruit
December 23, 2025 at 12:49 PM
We keep rocking the #AOTYCountdown!
3422. Subskile
3421. The MARX
3420. wav-dr.
3419. The Peace Lilies
3418. So Called Chris
3417. Onika Venus
3416. Irish Handcuffs
3415. Art of Chaos
3414. Atrip
3413. Olabayo
3412. Thieves Of Liberty
3411. The Voublys
3410. Janine Fourie
3409. Chris Spruit
3422. Subskile
3421. The MARX
3420. wav-dr.
3419. The Peace Lilies
3418. So Called Chris
3417. Onika Venus
3416. Irish Handcuffs
3415. Art of Chaos
3414. Atrip
3413. Olabayo
3412. Thieves Of Liberty
3411. The Voublys
3410. Janine Fourie
3409. Chris Spruit
Then let me suggest the Red Mountain Orach, Atriplex hortensis rubra, a morose mahogany-coloured spinach, no flower but richly decorative as a dark foil of foliage; and you can eat it in salads. #gardening
www.gardenersworld.com/plants/atrip...
www.gardenersworld.com/plants/atrip...
February 5, 2025 at 12:19 PM
Then let me suggest the Red Mountain Orach, Atriplex hortensis rubra, a morose mahogany-coloured spinach, no flower but richly decorative as a dark foil of foliage; and you can eat it in salads. #gardening
www.gardenersworld.com/plants/atrip...
www.gardenersworld.com/plants/atrip...
New online: Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase
Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase
Nature Structural & Molecular Biology, Published online: 23 July 2026; doi:10.1038/s41594-026-01844-1Li et al. present cryo-EM structures of the ATR–ATRIP complex bound to the ATR-activating domains of TOPBP1 and ETAA1; these reveal distinct binding modes and allosteric mechanism of activation for TOPBP1 and ETAA1.
dlvr.it
July 23, 2026 at 9:26 AM
New online: Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase