? Nossaq uer abeta apetitosa
March 30, 2025 at 7:01 PM
? Nossaq uer abeta apetitosa
#fluorescencefriday brings you a cleared AD mouse 🧠 stained for Abeta (green) and vasculature (magenta). Colocalization is white. #lightsheetmicroscopy
👀 for Abeta in blood vessels to test for CAA or micro bleeding. Courtesy of @shahrzadbahrampour.bsky.social Luke Smolders and Arash Salahinejad
👀 for Abeta in blood vessels to test for CAA or micro bleeding. Courtesy of @shahrzadbahrampour.bsky.social Luke Smolders and Arash Salahinejad
March 21, 2025 at 5:47 PM
#fluorescencefriday brings you a cleared AD mouse 🧠 stained for Abeta (green) and vasculature (magenta). Colocalization is white. #lightsheetmicroscopy
👀 for Abeta in blood vessels to test for CAA or micro bleeding. Courtesy of @shahrzadbahrampour.bsky.social Luke Smolders and Arash Salahinejad
👀 for Abeta in blood vessels to test for CAA or micro bleeding. Courtesy of @shahrzadbahrampour.bsky.social Luke Smolders and Arash Salahinejad
late for #fluorescenceFriday. Here are our efforts to look at blood vessels in the 🧠 and of course Abeta plaques @touchscreencog.bsky.social @tridentpct.bsky.social
July 18, 2025 at 10:39 PM
late for #fluorescenceFriday. Here are our efforts to look at blood vessels in the 🧠 and of course Abeta plaques @touchscreencog.bsky.social @tridentpct.bsky.social
Video von der Besetzung am Anfang des Abends in #Leipzig #Le1010 #Henri #Besetzung #Besetzungstage #abeta #abetaleipzig:
October 10, 2025 at 7:54 PM
Video von der Besetzung am Anfang des Abends in #Leipzig #Le1010 #Henri #Besetzung #Besetzungstage #abeta #abetaleipzig:
#fluorescencefriday Preliminary data. We used a mouse version of lecanemab in a new Apoe4 AD 🐁 model. 3D cleared 🧠 labelled for abeta- images with lightsheet microscopy. As in humans, the antibody is effective to clear Abeta. But does it improve cognition? Does it cause micro bleeding? wait and see…
March 28, 2025 at 5:52 PM
#fluorescencefriday Preliminary data. We used a mouse version of lecanemab in a new Apoe4 AD 🐁 model. 3D cleared 🧠 labelled for abeta- images with lightsheet microscopy. As in humans, the antibody is effective to clear Abeta. But does it improve cognition? Does it cause micro bleeding? wait and see…
For #fluorescenceFriday first attempt to label blood vessels (CD31) and Abeta in ApoE4 AD mouse model Courtesy of @kesummers.bsky.social and @shahrzadbahrampour.bsky.social #lightsheet #microscopy
February 7, 2025 at 8:11 PM
For #fluorescenceFriday first attempt to label blood vessels (CD31) and Abeta in ApoE4 AD mouse model Courtesy of @kesummers.bsky.social and @shahrzadbahrampour.bsky.social #lightsheet #microscopy
#fluorescencefriday microglia (yellow) and Abeta plaques (magenta) in our AD mouse model in 3D from a cleared 🧠 using @lifecanvastech.bsky.social SHIELD Courtesy of @shahrzadbahrampour.bsky.social and @nadiahaghbinphd.bsky.social with @mind-western.bsky.social and @neuroak.bsky.social Low-res.
December 12, 2025 at 2:04 PM
#fluorescencefriday microglia (yellow) and Abeta plaques (magenta) in our AD mouse model in 3D from a cleared 🧠 using @lifecanvastech.bsky.social SHIELD Courtesy of @shahrzadbahrampour.bsky.social and @nadiahaghbinphd.bsky.social with @mind-western.bsky.social and @neuroak.bsky.social Low-res.
#fluorescencefriday courtesy of Alycia Crooks abeta plaques (magenta) surrounded by microglia labeled with IBA1 (cyan) and CD68 (green)
September 26, 2025 at 10:33 AM
#fluorescencefriday courtesy of Alycia Crooks abeta plaques (magenta) surrounded by microglia labeled with IBA1 (cyan) and CD68 (green)
For #fluorescencefriday the Mesoscopic Integrated NeuroImaging Data (MIND) platform @westernu.bsky.social presents abeta plaques and blood vessels in the 🧠 of our ApoE4 mouse model of AD. 🧪 #clearing #lightsheet 🔬 Courtesy of Arash Salahinejad, Luke Smolders and @shahrzadbahrampour.bsky.social
June 13, 2025 at 5:35 PM
For #fluorescencefriday the Mesoscopic Integrated NeuroImaging Data (MIND) platform @westernu.bsky.social presents abeta plaques and blood vessels in the 🧠 of our ApoE4 mouse model of AD. 🧪 #clearing #lightsheet 🔬 Courtesy of Arash Salahinejad, Luke Smolders and @shahrzadbahrampour.bsky.social
Busy tomorrow so getting some images prepared by @shahrzadbahrampour.bsky.social out for #fluorescencefriday blood vessels and abeta in vehicle and lecanemab-treated App APOE4 and tau humanized 🐁 (which I presented by zoom earlier today at #ADPD2025 )
April 3, 2025 at 10:33 PM
Busy tomorrow so getting some images prepared by @shahrzadbahrampour.bsky.social out for #fluorescencefriday blood vessels and abeta in vehicle and lecanemab-treated App APOE4 and tau humanized 🐁 (which I presented by zoom earlier today at #ADPD2025 )
Another really interesting piece about this trial- TREM2 antibody caused ARIAs in E4/E4 individuals. No change in abeta so does this suggest ARIA is independent of plaque removal?
Alector announced that its investigational agent AL002, a TREM2-targeting therapy, did not meet primary, secondary, or exploratory end points in the phase 2 INVOKE-2 trial (NCT04592874) in early AD.
company is stopping the long-term extension study.1
www.neurologylive.com/view/al002-f...
company is stopping the long-term extension study.1
www.neurologylive.com/view/al002-f...
AL002 Falls Short in Phase 2 INVOKE-2 Trial of Early Alzheimer Disease
AL002 did not meet the primary endpoint of slowing Alzheimer's clinical progression, as measured by the Clinical Dementia Rating Sum of Boxes and showed no treatment effects on secondary clinical and ...
www.neurologylive.com
December 1, 2024 at 12:36 PM
Another really interesting piece about this trial- TREM2 antibody caused ARIAs in E4/E4 individuals. No change in abeta so does this suggest ARIA is independent of plaque removal?
The @mind-western.bsky.social #fluorescencefriday entry focus on the hippocampus of an aggressive AD model Appnl-g-f with IBA1 (yellow) and abeta (magenta). thanks to @shahrzadbahrampour.bsky.social @nadiahaghbinphd.bsky.social and @kesummers.bsky.social
March 27, 2026 at 6:37 PM
The @mind-western.bsky.social #fluorescencefriday entry focus on the hippocampus of an aggressive AD model Appnl-g-f with IBA1 (yellow) and abeta (magenta). thanks to @shahrzadbahrampour.bsky.social @nadiahaghbinphd.bsky.social and @kesummers.bsky.social
Excited to share new work from the lab showing that loss of AD risk gene Ms4a4a promotes abeta clearance and protects against amyloid plaque accumulation in a mouse model 🧠🐭 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
alz-journals.onlinelibrary.wiley.com
October 21, 2025 at 1:06 AM
Excited to share new work from the lab showing that loss of AD risk gene Ms4a4a promotes abeta clearance and protects against amyloid plaque accumulation in a mouse model 🧠🐭 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Immunostaining of a Alzheimer's disease mouse brain with Aquaporin 4 🔴, P2Y12 🟢, APP 🟡 and Abeta 🟣.
#FluorescenceFriday
#neuroscience
#FluorescenceFriday
#neuroscience
May 9, 2025 at 1:29 PM
Immunostaining of a Alzheimer's disease mouse brain with Aquaporin 4 🔴, P2Y12 🟢, APP 🟡 and Abeta 🟣.
#FluorescenceFriday
#neuroscience
#FluorescenceFriday
#neuroscience
Solidarität mit ABeTa und Prosfygika
Solidarität mit ABeTa und Prosfygika
www.anarchistischefoderation.de
October 18, 2025 at 6:42 PM
Solidarität mit ABeTa und Prosfygika
Alzheimer’s disease features amyloid-beta (Abeta) plaques, ApoE-driven amyloid buildup, and Caveolin1-modulated APP processing. IBA1 marks activated microglia clustering near plaques, fueling immune and inflammatory responses that accelerate neurodegeneration.
#FluorescenceFriday
#Neuroscience
#FluorescenceFriday
#Neuroscience
October 24, 2025 at 4:05 PM
Alzheimer’s disease features amyloid-beta (Abeta) plaques, ApoE-driven amyloid buildup, and Caveolin1-modulated APP processing. IBA1 marks activated microglia clustering near plaques, fueling immune and inflammatory responses that accelerate neurodegeneration.
#FluorescenceFriday
#Neuroscience
#FluorescenceFriday
#Neuroscience
September 22, 2026 at 9:00 AM
Aus dem Ticker:
Scheinbesetzung in Eythraer str. 2 :)
abeta.noblogs.org
#le1410 #Besetzung #abeta #abetaleipzig #leipzigbesetzen #Leipzig
Scheinbesetzung in Eythraer str. 2 :)
abeta.noblogs.org
#le1410 #Besetzung #abeta #abetaleipzig #leipzigbesetzen #Leipzig
#ABeTa | squat the world!
abeta.noblogs.org
October 14, 2025 at 2:45 PM
Aus dem Ticker:
Scheinbesetzung in Eythraer str. 2 :)
abeta.noblogs.org
#le1410 #Besetzung #abeta #abetaleipzig #leipzigbesetzen #Leipzig
Scheinbesetzung in Eythraer str. 2 :)
abeta.noblogs.org
#le1410 #Besetzung #abeta #abetaleipzig #leipzigbesetzen #Leipzig
Love this. I'm always puzzled by physiological v pathological abeta, tau, & ptau. This is a cool study looking at physiological v pathological abeta on synapses.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures - Nature Communications
Understanding synapse loss in Alzheimer’s disease has been hampered by a lack of human model systems. Here, the authors show that manipulation of physiological or pathological Aβ has differing effects...
www.nature.com
April 30, 2025 at 12:14 PM
Love this. I'm always puzzled by physiological v pathological abeta, tau, & ptau. This is a cool study looking at physiological v pathological abeta on synapses.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Aus dem Ticker:
22:10 Uhr: Cops sind jetzt im Hinterhof
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
22:10 Uhr: Cops sind jetzt im Hinterhof
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
October 10, 2025 at 8:13 PM
Aus dem Ticker:
22:10 Uhr: Cops sind jetzt im Hinterhof
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
22:10 Uhr: Cops sind jetzt im Hinterhof
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
+++ Statement und Infos zur Räumung der #Henri' am 10.10.2025+++ #Leipzig #le1010 #Besetzung #abeta #abetaleipzig #leipzigbesetzen
abeta.noblogs.org
Gestern Abend wurde die Besetzung 'Henri' nach sechseinhalb Stunden durch die Polizei geräumt.
abeta.noblogs.org
Gestern Abend wurde die Besetzung 'Henri' nach sechseinhalb Stunden durch die Polizei geräumt.
#ABeTa | squat the world!
abeta.noblogs.org
October 11, 2025 at 2:50 PM
+++ Statement und Infos zur Räumung der #Henri' am 10.10.2025+++ #Leipzig #le1010 #Besetzung #abeta #abetaleipzig #leipzigbesetzen
abeta.noblogs.org
Gestern Abend wurde die Besetzung 'Henri' nach sechseinhalb Stunden durch die Polizei geräumt.
abeta.noblogs.org
Gestern Abend wurde die Besetzung 'Henri' nach sechseinhalb Stunden durch die Polizei geräumt.
Aus dem Ticker:
21:52 Uhr: Cops spähen mit Lampen den Hinterhof aus.
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
21:52 Uhr: Cops spähen mit Lampen den Hinterhof aus.
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
October 10, 2025 at 7:56 PM
Aus dem Ticker:
21:52 Uhr: Cops spähen mit Lampen den Hinterhof aus.
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
21:52 Uhr: Cops spähen mit Lampen den Hinterhof aus.
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
Aus dem Ticker:
22:26 Uhr: cops sind aus unserem garten raus aber stehen im benachbarten hinterhof (richtung henriettenstraße)
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
22:26 Uhr: cops sind aus unserem garten raus aber stehen im benachbarten hinterhof (richtung henriettenstraße)
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
October 10, 2025 at 8:31 PM
Aus dem Ticker:
22:26 Uhr: cops sind aus unserem garten raus aber stehen im benachbarten hinterhof (richtung henriettenstraße)
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen
22:26 Uhr: cops sind aus unserem garten raus aber stehen im benachbarten hinterhof (richtung henriettenstraße)
#Leipzig #le1010 #Besetzung #Henri #abeta #abetaleipzig #leipzigbesetzen