Influenza A virus induces Lung cell senescence in vivo

Infected macrophage conditioned medium⏩
Paracrine Senescence of lung fibroblast (IMR90)

Lung fibroblasts+TNFα are susceptible to IAV infection
~4.5-fold⏫viral titer
⏫IAV nucleoprotein

#AgingDis 2023
www.aginganddisease.org/EN/10.14336/...