Galerina marginata (funeral bell) photographed last week in San Mateo County, California. This deadly mushroom is common on well decayed wood and contains α-amanitin and β-amanitin at similar concentrations to death caps. To me, they taste like cucumber.
iNat 254940148 / MO 567962
#fungifriends
iNat 254940148 / MO 567962
#fungifriends
December 13, 2024 at 12:38 AM
Galerina marginata (funeral bell) photographed last week in San Mateo County, California. This deadly mushroom is common on well decayed wood and contains α-amanitin and β-amanitin at similar concentrations to death caps. To me, they taste like cucumber.
iNat 254940148 / MO 567962
#fungifriends
iNat 254940148 / MO 567962
#fungifriends
you're right, that was alpha-amanitin that you synthesized, which is why your liver and kidneys are failing after consuming it. that's on me.
my bad.
my bad.
September 9, 2026 at 3:57 AM
you're right, that was alpha-amanitin that you synthesized, which is why your liver and kidneys are failing after consuming it. that's on me.
my bad.
my bad.
For #FebruARTy and #artyear From Wikipedia: "α-Amanitin (alpha-Amanitin) is a cyclic peptide of eight amino acids. It is possibly the most deadly of all the amatoxins, toxins found in several species of the mushroom genus Amanita."
#sciart #fungifriends #mushroomsky #mycology
#sciart #fungifriends #mushroomsky #mycology
February 19, 2025 at 1:44 PM
For #FebruARTy and #artyear From Wikipedia: "α-Amanitin (alpha-Amanitin) is a cyclic peptide of eight amino acids. It is possibly the most deadly of all the amatoxins, toxins found in several species of the mushroom genus Amanita."
#sciart #fungifriends #mushroomsky #mycology
#sciart #fungifriends #mushroomsky #mycology
No Tox Tuesday today, sorry. But here's a Fountain Pen & Ink structure. I had an awesome poem to go along with it, but there were too many characters 😔. Amanitin is the toxin of "Death Cap" mushrooms ☠️
March 4, 2025 at 1:17 PM
No Tox Tuesday today, sorry. But here's a Fountain Pen & Ink structure. I had an awesome poem to go along with it, but there were too many characters 😔. Amanitin is the toxin of "Death Cap" mushrooms ☠️
MY STUDENTS ARE AMAZING!
Here’s our group costume! We are dressed as….alpha-amanitin, the most deadly (and my favourite) protein produced by fungi. 🍄
Here’s our group costume! We are dressed as….alpha-amanitin, the most deadly (and my favourite) protein produced by fungi. 🍄
October 31, 2023 at 5:58 PM
MY STUDENTS ARE AMAZING!
Here’s our group costume! We are dressed as….alpha-amanitin, the most deadly (and my favourite) protein produced by fungi. 🍄
Here’s our group costume! We are dressed as….alpha-amanitin, the most deadly (and my favourite) protein produced by fungi. 🍄
Ja, der enthält wenig Amanitin und Bufotenin. Aber von dem stirbt man nicht.
September 24, 2026 at 11:31 AM
Ja, der enthält wenig Amanitin und Bufotenin. Aber von dem stirbt man nicht.
#fungifact 🍄📷 Der Gifthäubling Galerina marginata enthält wie der Knollenblätterpilz Amanitin und ist tödlich giftig (100-150g Frischpilz für einen Erwachsenen, ca 10 Fruchtkörper für ein Kind). Das Stockschwämmchen, ein exzellenter Speisepilz, ist ein Doppelgänger des Gifthäublings,...
December 30, 2023 at 5:21 AM
#fungifact 🍄📷 Der Gifthäubling Galerina marginata enthält wie der Knollenblätterpilz Amanitin und ist tödlich giftig (100-150g Frischpilz für einen Erwachsenen, ca 10 Fruchtkörper für ein Kind). Das Stockschwämmchen, ein exzellenter Speisepilz, ist ein Doppelgänger des Gifthäublings,...
Amatoxins are somewhat terrifying. What they do is scramble RNA, disrupt protein synthesis, and kick off cell death. But there is one application where something that might be useful (if you can make it at least a bit targeted) - chemotherapy. 🧪
Link: link.springer.com/article/10.1...
Link: link.springer.com/article/10.1...
January 22, 2026 at 6:05 AM
Amatoxins are somewhat terrifying. What they do is scramble RNA, disrupt protein synthesis, and kick off cell death. But there is one application where something that might be useful (if you can make it at least a bit targeted) - chemotherapy. 🧪
Link: link.springer.com/article/10.1...
Link: link.springer.com/article/10.1...
The genus Amanita contains the most deadly fungal species, the death caps. These fungi contain the toxin alpha-amanitin which binds to the RNA polymerase II basically stopping your cells from working. The toxin destroys your liver and despite modern medicine 15-25% of cases are fatal. 2/3 🍄📷🧪🦠
November 19, 2024 at 4:54 AM
The genus Amanita contains the most deadly fungal species, the death caps. These fungi contain the toxin alpha-amanitin which binds to the RNA polymerase II basically stopping your cells from working. The toxin destroys your liver and despite modern medicine 15-25% of cases are fatal. 2/3 🍄📷🧪🦠
Die Gattung Amanita enthält die tödlichsten Pilze, Knollenblätterpilz. Diese enthalten das Gift Alpha-Amanitin, das an die RNA-Polymerase II bindet und Zellen daran hindert, zu funktionieren. Das Toxin zerstört Ihre Leber und trotz moderner Medizin enden 15–25 % der Fälle tödlich. 2/3
November 19, 2024 at 5:05 AM
Die Gattung Amanita enthält die tödlichsten Pilze, Knollenblätterpilz. Diese enthalten das Gift Alpha-Amanitin, das an die RNA-Polymerase II bindet und Zellen daran hindert, zu funktionieren. Das Toxin zerstört Ihre Leber und trotz moderner Medizin enden 15–25 % der Fälle tödlich. 2/3
I've got the sauce:
1. brush with doramand
2. rinse with radium wodder
3. mix some α-Amanitin in the rinse water.
Profit?
disclaimer: for the sane people reading this (I'm not really worried about y'all but) DO NOT EVER EVER DO THIS.
1. brush with doramand
2. rinse with radium wodder
3. mix some α-Amanitin in the rinse water.
Profit?
disclaimer: for the sane people reading this (I'm not really worried about y'all but) DO NOT EVER EVER DO THIS.
October 4, 2026 at 6:21 PM
I've got the sauce:
1. brush with doramand
2. rinse with radium wodder
3. mix some α-Amanitin in the rinse water.
Profit?
disclaimer: for the sane people reading this (I'm not really worried about y'all but) DO NOT EVER EVER DO THIS.
1. brush with doramand
2. rinse with radium wodder
3. mix some α-Amanitin in the rinse water.
Profit?
disclaimer: for the sane people reading this (I'm not really worried about y'all but) DO NOT EVER EVER DO THIS.
Disappearing atom label bug strikes again. On the late news the ongoing trial of the woman accused of poisoning her guests with a laced beef Wellington. Featuring this backdrop of what I clocked instantly as alpha-amanitin. #chemsky 🧪
May 6, 2025 at 1:17 PM
Disappearing atom label bug strikes again. On the late news the ongoing trial of the woman accused of poisoning her guests with a laced beef Wellington. Featuring this backdrop of what I clocked instantly as alpha-amanitin. #chemsky 🧪
The Death Cap (Amanita phalloides) is the most poisonous of all mushrooms, responsible for 90% of fungi-related deaths each year. Famous victims include Emperor Claudius and Holy Roman Emperor Charles VI. The toxic constituent is α-Amanitin, which causes liver and kidney failure. #fungifriends 🍄
November 17, 2024 at 8:45 PM
The Death Cap (Amanita phalloides) is the most poisonous of all mushrooms, responsible for 90% of fungi-related deaths each year. Famous victims include Emperor Claudius and Holy Roman Emperor Charles VI. The toxic constituent is α-Amanitin, which causes liver and kidney failure. #fungifriends 🍄
Another species ofAgarics, including some of the most potent toxins, a-Amanitin.
There are also members of the species of agarics that are edible.
There are also members of the species of agarics that are edible.
November 18, 2024 at 1:59 AM
Another species ofAgarics, including some of the most potent toxins, a-Amanitin.
There are also members of the species of agarics that are edible.
There are also members of the species of agarics that are edible.
No moar mRNA for me! Amanitin to the rescue!
A twice-weekly cocktail of three messenger RNAs can rejuvenate the weary immune systems of aged mice and boost responses to vaccination and cancer treatments
go.nature.com/497jGuw
go.nature.com/497jGuw
Restoring youth to old immune cells: mRNA therapy turns back the clock.
Nature - Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
go.nature.com
December 21, 2025 at 12:22 PM
No moar mRNA for me! Amanitin to the rescue!
These people should take alpha-amanitin if they are afraid of mRNA!!!
April 22, 2025 at 3:21 AM
These people should take alpha-amanitin if they are afraid of mRNA!!!
@matsudaphdphd.bsky.social thanks for following!
You might like my post about ADCs and how Amanitin toxin from Death Cap mushroom is in clinical trials as an ADC warhead for the treatment of multiple myeloma.
www.kathryngarner.co.uk/blog/the-wor...
You might like my post about ADCs and how Amanitin toxin from Death Cap mushroom is in clinical trials as an ADC warhead for the treatment of multiple myeloma.
www.kathryngarner.co.uk/blog/the-wor...
January 29, 2025 at 7:49 AM
@matsudaphdphd.bsky.social thanks for following!
You might like my post about ADCs and how Amanitin toxin from Death Cap mushroom is in clinical trials as an ADC warhead for the treatment of multiple myeloma.
www.kathryngarner.co.uk/blog/the-wor...
You might like my post about ADCs and how Amanitin toxin from Death Cap mushroom is in clinical trials as an ADC warhead for the treatment of multiple myeloma.
www.kathryngarner.co.uk/blog/the-wor...
Next up in the Montana legislature: universal access to free alpha-amanitin now!
February 19, 2025 at 8:51 PM
Next up in the Montana legislature: universal access to free alpha-amanitin now!
As an avid #mushroom hunter, I am acutely aware of the deadly toxin, alpha-amanitin, which is found in death cap mushrooms. A forager learns to identify the deadly mushrooms first!
Noah’s article describes how this toxin is being studied for cancer treatments. 🤯
Noah’s article describes how this toxin is being studied for cancer treatments. 🤯
June 5, 2025 at 6:53 PM
As an avid #mushroom hunter, I am acutely aware of the deadly toxin, alpha-amanitin, which is found in death cap mushrooms. A forager learns to identify the deadly mushrooms first!
Noah’s article describes how this toxin is being studied for cancer treatments. 🤯
Noah’s article describes how this toxin is being studied for cancer treatments. 🤯
alpha-amanitin? aflatoxins?
People have a very romantic view of nature…
People have a very romantic view of nature…
November 22, 2024 at 8:55 AM
alpha-amanitin? aflatoxins?
People have a very romantic view of nature…
People have a very romantic view of nature…
Not forgetting Pierre Chambon's 1970 paper which used the differential sensitivities of the three RNA polymerases to the mushroom toxin α-amanitin to further characterize the differences between them.
November 24, 2024 at 10:59 AM
Not forgetting Pierre Chambon's 1970 paper which used the differential sensitivities of the three RNA polymerases to the mushroom toxin α-amanitin to further characterize the differences between them.
This year I’m going to be dressed as me, but holding a bottle of tonic water. I’ll let you figure out what that means.
Last year I made my students dress up with me in a group costume: we were each a codon/amino acid of the wee protein alpha-Amanitin (which will kill you, and we slayed)
Last year I made my students dress up with me in a group costume: we were each a codon/amino acid of the wee protein alpha-Amanitin (which will kill you, and we slayed)
I know it's August, but here's a free geology Halloween costume idea:
A sports jersey and cheer pompom and foam finger, but they're all gray/brown and say "sediment" instead of a team name.
You'd be an alluvial fan.
A sports jersey and cheer pompom and foam finger, but they're all gray/brown and say "sediment" instead of a team name.
You'd be an alluvial fan.
August 27, 2024 at 8:47 PM
This year I’m going to be dressed as me, but holding a bottle of tonic water. I’ll let you figure out what that means.
Last year I made my students dress up with me in a group costume: we were each a codon/amino acid of the wee protein alpha-Amanitin (which will kill you, and we slayed)
Last year I made my students dress up with me in a group costume: we were each a codon/amino acid of the wee protein alpha-Amanitin (which will kill you, and we slayed)
The amanitin-containing mushrooms like A. phalliodes (death cap), destroying angel, etc. are so terrifying. Minor symptoms until about a week after ingestion your organs shut down, you go into a coma, and you die.
August 16, 2024 at 6:38 PM
The amanitin-containing mushrooms like A. phalliodes (death cap), destroying angel, etc. are so terrifying. Minor symptoms until about a week after ingestion your organs shut down, you go into a coma, and you die.