#AnalBiochem
Untargeted metabolomic and lipidomic profiling in a hyperuricemic rabbit model: a pilot study #AnalBiochem #MassSpec www.sciencedirect.com/science/arti...
Untargeted metabolomic and lipidomic profiling in a hyperuricemic rabbit model: a pilot study
The incidence of hyperuricemia is rising globally; however, its molecular mechanisms and reliable progression biomarkers remain unclear. This study ch…
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February 3, 2026 at 7:56 PM
Ammonium bicarbonate buffer system for DNA hybridization and quantification by LC-ESI-MS/MS #AnalBiochem www.sciencedirect.com/science/arti...
Ammonium bicarbonate buffer system for DNA hybridization and quantification by LC-ESI-MS/MS
High salt buffer may be used for the UV/VIS or radiometric based detection of trihybrid DNA but would contaminate the electrospray mass spectrometer. …
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March 6, 2025 at 8:11 AM
Advancing protein heterogeneity analysis: nano-flow pressure mobilization for precise icIEF fractionation and online MS detection #AnalBiochem www.sciencedirect.com/science/arti...
Advancing protein heterogeneity analysis: nano-flow pressure mobilization for precise icIEF fractionation and online MS detection
This study addresses the challenges of high-resolution protein charge variant fractionation and efficient online mass spectrometry (MS) detection in i…
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March 3, 2025 at 10:25 AM
Simultaneous determination of 25(OH)D2, 25(OH)D3 and 1α,25(OH)2D3 in human serum by derivatization-liquid chromatography-tandem mass spectrometry #AnalBiochem www.sciencedirect.com/science/arti...
Simultaneous determination of 25(OH)D2, 25(OH)D3 and 1α,25(OH)2D3 in human serum by derivatization-liquid chromatography-tandem mass spectrometry
An LC-MS/MS method was developed and validated for simultaneously quantifying 25-hydroxyvitamin D2, D3, and 1α,25-dihydroxyvitamin D3 in human serum. …
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February 24, 2025 at 7:00 PM
In-depth characterization and semi-quantification of anti-drug antibodies in clinical samples using specific hybrid IC-LC-MS/MS methods. #AnalBiochem www.sciencedirect.com/science/arti...
In-depth characterization and semi-quantification of anti-drug antibodies in clinical samples using specific hybrid IC-LC-MS/MS methods.
Anti-drug antibodies (ADAs) generated by biotherapeutics can impair the drug clearance, prevent the binding to its target or lead to hypersensitivity …
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February 6, 2025 at 10:08 AM
Quantification of amyloid-β aggregation inhibitors gallic acid and rosmarinic acid in biological samples by LC-MS/MS #AnalBiochem www.sciencedirect.com/science/arti...
Quantification of amyloid-β aggregation inhibitors gallic acid and rosmarinic acid in biological samples by LC-MS/MS
The decline of the cognitive functions encountered at patients diagnosed with Alzheimer’s disease (AD) together with the findings of extracellular amy…
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February 4, 2025 at 8:15 AM
Effects of the physico-chemical properties of amino acids and chemically functionalized surfaces on DIOS-MS analysis. #AnalBiochem www.sciencedirect.com/science/arti...
Effects of the physico-chemical properties of amino acids and chemically functionalized surfaces on DIOS-MS analysis.
Desorption ionisation on silicon mass spectrometry (DIOS-MS) allows for the detection of low molecular weight species from fluid samples. However, thi…
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January 31, 2025 at 7:58 AM