New paper from our lab @naturecomms.bsky.social!
We reveal the dynamics and mechanism of target DNA traversal in #CRISPR Cas12a, a conundrum in the field!
nature.com/articles/s41...
#compchem
We thank the amazing #HPC resources of PSC #Anton2 and SDSC
We reveal the dynamics and mechanism of target DNA traversal in #CRISPR Cas12a, a conundrum in the field!
nature.com/articles/s41...
#compchem
We thank the amazing #HPC resources of PSC #Anton2 and SDSC
February 8, 2025 at 6:22 PM
New paper from our lab @naturecomms.bsky.social!
We reveal the dynamics and mechanism of target DNA traversal in #CRISPR Cas12a, a conundrum in the field!
nature.com/articles/s41...
#compchem
We thank the amazing #HPC resources of PSC #Anton2 and SDSC
We reveal the dynamics and mechanism of target DNA traversal in #CRISPR Cas12a, a conundrum in the field!
nature.com/articles/s41...
#compchem
We thank the amazing #HPC resources of PSC #Anton2 and SDSC
Haven't used GROMACS in what feels like a lifetime, but I remember trjconv had a bunch of different ways to help you reimage trajectories?
For openmm I used to use mdtraj to reimage: gist.github.com/JoaoRodrigue...
For openmm I used to use mdtraj to reimage: gist.github.com/JoaoRodrigue...
Script to reimage Anton2 trajectories
Script to reimage Anton2 trajectories. GitHub Gist: instantly share code, notes, and snippets.
gist.github.com
December 13, 2024 at 5:01 PM
Haven't used GROMACS in what feels like a lifetime, but I remember trjconv had a bunch of different ways to help you reimage trajectories?
For openmm I used to use mdtraj to reimage: gist.github.com/JoaoRodrigue...
For openmm I used to use mdtraj to reimage: gist.github.com/JoaoRodrigue...
🔥🔥 NEW SPEEDRUN RECORD VERIFIED! 🔥🔥
🎮 Game: Mondays, Am I Right?
🏆 Category: All Endings
⏱ Time: 0h 17m 14s 000ms
👤 Player: Anton2
🔗 Link: https://www.speedrun.com/Mondays_Am_I_Right/run/y8gqplwz
🎮 Game: Mondays, Am I Right?
🏆 Category: All Endings
⏱ Time: 0h 17m 14s 000ms
👤 Player: Anton2
🔗 Link: https://www.speedrun.com/Mondays_Am_I_Right/run/y8gqplwz
April 29, 2025 at 12:52 PM
🔥🔥 NEW SPEEDRUN RECORD VERIFIED! 🔥🔥
🎮 Game: Mondays, Am I Right?
🏆 Category: All Endings
⏱ Time: 0h 17m 14s 000ms
👤 Player: Anton2
🔗 Link: https://www.speedrun.com/Mondays_Am_I_Right/run/y8gqplwz
🎮 Game: Mondays, Am I Right?
🏆 Category: All Endings
⏱ Time: 0h 17m 14s 000ms
👤 Player: Anton2
🔗 Link: https://www.speedrun.com/Mondays_Am_I_Right/run/y8gqplwz
Mondays, Am I Right? - All Endings in 17:14 by Anton2
Mondays, Am I Right? - All Endings in 17:14 by Anton2
www.speedrun.com
April 29, 2025 at 12:35 PM
Mondays, Am I Right? - All Endings in 17:14 by Anton2
Anton1 ruft Anton2 und Anton2 ruft Anton3 und Anton3 ruft Anton4
zur Behördlichenübergreifeinden Aktion #Peršmanhof
#Gedenkstätte #Museum
zur Behördlichenübergreifeinden Aktion #Peršmanhof
#Gedenkstätte #Museum
Ich bin ganz sicher, eine ähnlicher Polizeieinsatz gegen die Sonnwendfeier eines „patriotischen Jugendlagers“ wäre von der FPÖ nicht anders kommentiert worden:
July 29, 2025 at 10:06 AM
Anton1 ruft Anton2 und Anton2 ruft Anton3 und Anton3 ruft Anton4
zur Behördlichenübergreifeinden Aktion #Peršmanhof
#Gedenkstätte #Museum
zur Behördlichenübergreifeinden Aktion #Peršmanhof
#Gedenkstätte #Museum
So what does this look like an atomic, molecular level?
A single (or small number of) rigid binding interface(s)? Disordered binding? Fuzzy complexes?
Lets get an Anton2 grant and fire-up some unbiased 100 microsecond MD simulations of AR oligomerization in the presence and absence of ligands
A single (or small number of) rigid binding interface(s)? Disordered binding? Fuzzy complexes?
Lets get an Anton2 grant and fire-up some unbiased 100 microsecond MD simulations of AR oligomerization in the presence and absence of ligands
November 22, 2025 at 7:11 PM
So what does this look like an atomic, molecular level?
A single (or small number of) rigid binding interface(s)? Disordered binding? Fuzzy complexes?
Lets get an Anton2 grant and fire-up some unbiased 100 microsecond MD simulations of AR oligomerization in the presence and absence of ligands
A single (or small number of) rigid binding interface(s)? Disordered binding? Fuzzy complexes?
Lets get an Anton2 grant and fire-up some unbiased 100 microsecond MD simulations of AR oligomerization in the presence and absence of ligands