So, what flips the switch? 🚨
We identified a phage-encoded nuclease, B14T, that is sufficient to activate the system. This reveals a natural mechanism by which phage infection unleashes retron immunity ✂️🦠. (8/16)
We identified a phage-encoded nuclease, B14T, that is sufficient to activate the system. This reveals a natural mechanism by which phage infection unleashes retron immunity ✂️🦠. (8/16)
July 16, 2026 at 6:52 PM
So, what flips the switch? 🚨
We identified a phage-encoded nuclease, B14T, that is sufficient to activate the system. This reveals a natural mechanism by which phage infection unleashes retron immunity ✂️🦠. (8/16)
We identified a phage-encoded nuclease, B14T, that is sufficient to activate the system. This reveals a natural mechanism by which phage infection unleashes retron immunity ✂️🦠. (8/16)
Mechanistically, B14T cuts the msDNA at its base, preferentially targeting unpaired DNA ✂️🧬. This dismantles the ring, releasing the inhibited HEPN. But what does the RNase attack? 🤔 (9/16)
July 16, 2026 at 6:52 PM
Mechanistically, B14T cuts the msDNA at its base, preferentially targeting unpaired DNA ✂️🧬. This dismantles the ring, releasing the inhibited HEPN. But what does the RNase attack? 🤔 (9/16)
5/10
Escaper analysis revealed the trigger: a phage-encoded nuclease (B14T)
B14T snips the msDNA ✂️, the ring collapses 💥, and the RNase is released ⛓️💥. But what does it target?
Escaper analysis revealed the trigger: a phage-encoded nuclease (B14T)
B14T snips the msDNA ✂️, the ring collapses 💥, and the RNase is released ⛓️💥. But what does it target?
July 16, 2026 at 6:59 PM
5/10
Escaper analysis revealed the trigger: a phage-encoded nuclease (B14T)
B14T snips the msDNA ✂️, the ring collapses 💥, and the RNase is released ⛓️💥. But what does it target?
Escaper analysis revealed the trigger: a phage-encoded nuclease (B14T)
B14T snips the msDNA ✂️, the ring collapses 💥, and the RNase is released ⛓️💥. But what does it target?
ICAO: #AB53B9
Owner: #B14T
Flt: #EJA829 #N829QS #C700
Time: 2026-09-23 11:12:05 CDT
Min Alt: 23000 ft
Min Dist: 86.01 nm (100deg E)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
Owner: #B14T
Flt: #EJA829 #N829QS #C700
Time: 2026-09-23 11:12:05 CDT
Min Alt: 23000 ft
Min Dist: 86.01 nm (100deg E)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
September 23, 2026 at 4:30 PM
ICAO: #AB53B9
Owner: #B14T
Flt: #EJA829 #N829QS #C700
Time: 2026-09-23 11:12:05 CDT
Min Alt: 23000 ft
Min Dist: 86.01 nm (100deg E)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
Owner: #B14T
Flt: #EJA829 #N829QS #C700
Time: 2026-09-23 11:12:05 CDT
Min Alt: 23000 ft
Min Dist: 86.01 nm (100deg E)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
8/10
Why sense B14T? 🤔 Speculation: rec-like nucleases may help phages repair/recombine to escape DNA-targeting immunity.
Retron IX could act as a safeguard, detecting phages equipped to evade these defenses. Note it often co-occurs with DNA-targeting systems...
Why sense B14T? 🤔 Speculation: rec-like nucleases may help phages repair/recombine to escape DNA-targeting immunity.
Retron IX could act as a safeguard, detecting phages equipped to evade these defenses. Note it often co-occurs with DNA-targeting systems...
July 16, 2026 at 6:59 PM
8/10
Why sense B14T? 🤔 Speculation: rec-like nucleases may help phages repair/recombine to escape DNA-targeting immunity.
Retron IX could act as a safeguard, detecting phages equipped to evade these defenses. Note it often co-occurs with DNA-targeting systems...
Why sense B14T? 🤔 Speculation: rec-like nucleases may help phages repair/recombine to escape DNA-targeting immunity.
Retron IX could act as a safeguard, detecting phages equipped to evade these defenses. Note it often co-occurs with DNA-targeting systems...
ICAO: #A13C0B
Owner: #B14T
Flt: #EJA179 #N179QS #GL7T #BER-#DLM
Time: 2026-09-08 13:35:12 CDT
Min Alt: 1775 ft
Min Dist: 4.58 nm (-177deg S)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
Owner: #B14T
Flt: #EJA179 #N179QS #GL7T #BER-#DLM
Time: 2026-09-08 13:35:12 CDT
Min Alt: 1775 ft
Min Dist: 4.58 nm (-177deg S)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
September 8, 2026 at 6:44 PM
ICAO: #A13C0B
Owner: #B14T
Flt: #EJA179 #N179QS #GL7T #BER-#DLM
Time: 2026-09-08 13:35:12 CDT
Min Alt: 1775 ft
Min Dist: 4.58 nm (-177deg S)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
Owner: #B14T
Flt: #EJA179 #N179QS #GL7T #BER-#DLM
Time: 2026-09-08 13:35:12 CDT
Min Alt: 1775 ft
Min Dist: 4.58 nm (-177deg S)
#adsb #planefence by kx1t sdr-e adsbexchange flightaware faa
#Planefence ICAO: A13C0B
Flt: N179QS #B14T
First seen: 2025-05-20 12:48:07 EDT
Min Alt: 1591 ft AGL
Min Dist: 1.43 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence
Flt: N179QS #B14T
First seen: 2025-05-20 12:48:07 EDT
Min Alt: 1591 ft AGL
Min Dist: 1.43 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence
May 20, 2025 at 4:50 PM
#Planefence ICAO: A13C0B
Flt: N179QS #B14T
First seen: 2025-05-20 12:48:07 EDT
Min Alt: 1591 ft AGL
Min Dist: 1.43 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence
Flt: N179QS #B14T
First seen: 2025-05-20 12:48:07 EDT
Min Alt: 1591 ft AGL
Min Dist: 1.43 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence
#Planefence ICAO: A13C0B
Flt: N179QS #B14T
First seen: 2025-05-20 12:09:52 EDT
Min Alt: 441 ft AGL
Min Dist: 1.81 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence
Flt: N179QS #B14T
First seen: 2025-05-20 12:09:52 EDT
Min Alt: 441 ft AGL
Min Dist: 1.81 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence
May 20, 2025 at 4:12 PM
#Planefence ICAO: A13C0B
Flt: N179QS #B14T
First seen: 2025-05-20 12:09:52 EDT
Min Alt: 441 ft AGL
Min Dist: 1.81 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence
Flt: N179QS #B14T
First seen: 2025-05-20 12:09:52 EDT
Min Alt: 441 ft AGL
Min Dist: 1.81 nm
#dev #adsb #planefence by kx1t - airplanes.live - planefence