Zhang et al. present a web-based portal for exploring multimodal single-cell epigenomic datasets generated by the BICAN consortium. The platform integrates interactive genome browsing and comparative epigenomic visualization to make large-scale basal ganglia datasets more accessible for data exploration, interpretation, and reuse by the neuroscience community.

Explore a cross-species, multimodal atlas of the human, macaque, and marmoset basal ganglia from the NIH BRAIN Initiative Cell Atlas Network.

The BRAIN Initiative Cell Atlas Network (BICAN) is establishing an evolving reference for neuroscience by integrating cell identities, anatomy, and multimodal evidence across species. In analogy with ...

A Ten Million Dollar National Institutes of Health Grant Supported the Spatial Transcriptomics Mapping of Deep Human Brain Regions.

Read the full paper: An integrated single-cell and epigenomic resource for comparative analysis of the basal ganglia from BICAN

Berry et al. describe the establishment of UC Irvine’s Brain Procurement Program, a multi-institutional pipeline with standardized workflows to collect and process neurotypical donor brains for the NIH BRAIN Initiative Cell Atlas Network (BICAN). The authors show that this community-based model is feasible and scalable while noting challenges in recruiting neurotypical donors and achieving demographic representation of Southern California.

The BRAIN Initiative Cell Atlas Network (BICAN) is establishing an evolving reference for neuroscience by integrating cell identities, anatomy, and multimodal evidence across species. In analogy with the Human Genome Project, the BICAN basal ganglia atlas is a model for a federated reference to advance understanding of brain organization, function, variation, and disease.

BRAIN Initiative Cell Atlas Network Maps Basal Ganglia in Mammalian Brains

The BRAIN Initiative Cell Atlas Network integrates molecular profiles, spatial maps, and anatomical frameworks into a curated cell-type taxonomy of the human, macaque, and marmoset basal ganglia. This...

Explore BICAN’s cross-species cell atlas of the basal ganglia: 17.4M cells across human, macaque, marmoset, and mouse. Data, tools, and publications.

Úplně náhodou se veřejnost dozvěděla, že zemřel Ivan Bican, který se dost neortodoxně staral o dědictví nejslavnějšího fotbalisty československých dějin. Tátu Pepiho prodával za miliony a prakticky s ...

Science is collaborative by nature, but some questions require coordination on an exceptional scale. Among them is the challenge of creating a comprehensive reference framework for the human brain. In this issue of Cell, together with papers published in Cell Genomics, Cell Reports, Cell Reports Methods, Cell Systems, and Neuron, we present the first publication package from the NIH BRAIN Initiative Cell Atlas Network (BICAN).