UPLC-Q-TOF-MS/MS guided isolation of phyllanfranchins A–D, two pairs of undescribed cytotoxic dichapetalin hybrid triterpenoid epimers from Phyllanthus franchetianus #BioorgChem www.sciencedirect.com/science/arti...
UPLC-Q-TOF-MS/MS guided isolation of phyllanfranchins A–D, two pairs of undescribed cytotoxic dichapetalin hybrid triterpenoid epimers from Phyllanthus franchetianus
Four new dichapetalin hybrid triterpenoids, namely phyllanfranchins A–D (1–4), were obtained from the aerial part of Phyllanthus franchetianus H. L'ev…
www.sciencedirect.com
February 14, 2026 at 7:47 PM
UPLC-Q-TOF-MS/MS guided isolation of phyllanfranchins A–D, two pairs of undescribed cytotoxic dichapetalin hybrid triterpenoid epimers from Phyllanthus franchetianus #BioorgChem www.sciencedirect.com/science/arti...
Small molecule screening of RNA aptamers using native mass spectrometry #BioorgChem www.sciencedirect.com/science/arti...
Small molecule screening of RNA aptamers using native mass spectrometry
The intentional targeting of RNA with small molecules is recognized as a viable pathway to new therapeutics with potential to vastly expand the drugga…
www.sciencedirect.com
September 25, 2025 at 6:59 AM
Small molecule screening of RNA aptamers using native mass spectrometry #BioorgChem www.sciencedirect.com/science/arti...
HPLC-QTOF-MS-based chemical profiling of Pulicaria undulata and its influence on high-sucrose diet-induced diabetic-linked biochemical attributes and oxidative stress associated ovarian damage in Drosophila melanogaster #BioorgChem www.sciencedirect.com/science/arti...
HPLC-QTOF-MS-based chemical profiling of Pulicaria undulata and its influence on high-sucrose diet-induced diabetic-linked biochemical attributes and oxidative stress associated ovarian damage in Dros...
In the State of Qatar, Pulicaria undulata (L.) C.A.Mey (family: Asteraceae) has been traditionally used to treat various diseases, including diabetes.…
www.sciencedirect.com
August 22, 2025 at 9:08 AM
HPLC-QTOF-MS-based chemical profiling of Pulicaria undulata and its influence on high-sucrose diet-induced diabetic-linked biochemical attributes and oxidative stress associated ovarian damage in Drosophila melanogaster #BioorgChem www.sciencedirect.com/science/arti...
Integrating untargeted metabolomics and computational docking for biomarker evaluation: A case study on marine algae-derived ligands #BioorgChem #MassSpec www.sciencedirect.com/science/arti...
Integrating untargeted metabolomics and computational docking for biomarker evaluation: A case study on marine algae-derived ligands
In the post-genomic era, liquid chromatography-mass spectrometry (LC-MS) has emerged as a powerful tool for profiling metabolic profiles in marine mac…
www.sciencedirect.com
May 12, 2025 at 6:21 PM
Integrating untargeted metabolomics and computational docking for biomarker evaluation: A case study on marine algae-derived ligands #BioorgChem #MassSpec www.sciencedirect.com/science/arti...
Development of novel amino-benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors: Design, synthesis, anticancer activity assessment, and pharmacokinetic studies using UPLC-MS/MS #BioorgChem www.sciencedirect.com/science/arti...
Development of novel amino-benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors: Design, synthesis, anticancer activity assessment, and pharmacokinetic studies using UPL...
The present study outlines the design and synthesis of dual-tail analogues of SLC-0111 as carbonic anhydrase inhibitors (CAIs) targeting tumor isoform…
www.sciencedirect.com
March 15, 2025 at 9:27 AM
Development of novel amino-benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors: Design, synthesis, anticancer activity assessment, and pharmacokinetic studies using UPLC-MS/MS #BioorgChem www.sciencedirect.com/science/arti...
Metabolomic fingerprinting, molecular modelling and experimental bioprospection of Helianthus annuus seed cultivars as Pseudomonas aeruginosa LasR modulators #BioorgChem #MassSpec www.sciencedirect.com/science/arti...
Metabolomic fingerprinting, molecular modelling and experimental bioprospection of Helianthus annuus seed cultivars as Pseudomonas aeruginosa LasR modulators
The Pseudomonas aeruginosa LasR quorum sensing system (QSS) is central to regulating the expression of several pathogenicity factors. Also, while seed…
www.sciencedirect.com
December 19, 2024 at 6:56 PM
Metabolomic fingerprinting, molecular modelling and experimental bioprospection of Helianthus annuus seed cultivars as Pseudomonas aeruginosa LasR modulators #BioorgChem #MassSpec www.sciencedirect.com/science/arti...