#Leukocyte exploring the microenvironment videoed under a #microscope

This is what immune cells do in your body every day, they explore it in search of microbes and other danger signals

#CellMigration @cellcommlab.bsky.social @focalplane.bsky.social #BskySci 🧪🔬

re-intro to #BskySci 🧪🔬

I'm a cell biologist in love with microscopy, moving cells & organelles. I lead the @cellcommlab.bsky.social, so you know what we study ;)

I'll be posting #cellfies & movies of #cells
Let's make a nice community here!

We start with a classic: actin during #CellMigration

OMG finally home made .gifs are allowed here !!

Let's start the party then, with a classic of #CellMigration & #cytoskeleton

#BskySci #scicomm 🧪🔬 @cellcommlab.bsky.social @biologists.bsky.social

Not sure if the 1st time was posted as a video.
So, here we go again 👇🏽

#BskySci #scicomm 🧪🔬 @cellcommlab.bsky.social @biologists.bsky.social

Hurray! Mr. Millipede is here, BskySci Fans! (although I don't know why his first post is a centipede :D 🧪

Want to know how the microenvironment control immune cell responses?
Zahraa Alraies & co. show that confinement-induced changes in cell shape after cytoskeleton remodeling trigger #cellmigration in leukocytes

Full here @natureportfolio.bsky.social www.nature.com/articles/s41...
#BskySci #scicomm 🧪🔬

Cool paper for #BioImaging !
The multimodality cell segmentation challenge: toward universal solutions

Full: www.nature.com/articles/s41... #BskySci 🧪🔬

#scicomm 🔬🧪
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19
#BskySci

#hotfromthepress

Super cool data showing that #CellMigration of pericytes follows a dry friction model.

One of the most interesting cells I have recently worked with.

Sagnimorte et al full: www.biorxiv.org/content/10.1...
#scicomm @cellcommlab.bsky.social #bskysci 🧪🔬

How do #cells decide where to go @ a symmetrical junction?

In a HFSP founded project we found that @ a junction the membrane oscillates & actin #cystoskeleton accumulation define the new direction.
+ cancer cells decide much faster!

Full rdcu.be/dwj8o
Short www.hfsp.org/hfsp-news/os...
#bskysci 🧪🔬

For #CellMigration lovers
How do cells decide when facing a symmetric junction?
The membrane oscillates exploring both directions until one arm wins.
TLDR: this depends on the actin cytoskeleton & cancer cells decide faster than healthy cells #scicomm #bskysci 🧪🔬

Full www.nature.com/articles/s41...

Now that we can finally enjoy .gif in @bsky.app, let's start with a classic of #CellMigration

Here a movie of collective cell migration during wound healing videoed under a microscope.

#scicomm #bskysci 🧪🔬 @pjsaez.bsky.social

#preprint for #CellMigration lovers

We expanded our recently published model but now for cell moving a more complex network and spanning several junctions.
Spoiler: immune cells explore better the network than slow moving cells.

Full: www.biorxiv.org/content/10.1...
#scicomm #bskysci 🧪🔬