Understanding the mystery of the astrocyte: CADRC REC scholar Dr. Benjamin L.L. Clayton investigates new therapeutic targets for the rare genetic Alexander Disease.

CADRC REC Scholar Dr. Nikhil Panicker secures a $2.1M NIH R35 grant to study how immune cells transfer damaged mitochondria and spread inflammation.

For generations, the medical world has operated under a sobering assumption: once Alzheimer’s disease takes hold, the damage to the brain is permanent. Research has traditionally focused on building "roadblocks" to slow the disease down, rather than finding a way to turn the car around. However, a transformative new study led by Kalyani Chaubey, PhD, in the laboratory of CADRC co-Investigator…

Graduate student Carly Rose to present CADRC Data Management and Statistics Core research on COVID-19, Shingrix, and Alzheimer’s disease risk at the 2026 Keystone Symposia in Germany.

CADRC Clinical Core Leader, Dr. Brian Appleby, and collaborating researchers from NEOMED have been awareded $40k by the UH-NEOMED Brain Health Intramural Funding program for a new pilot research project titled "Decoding Alzheimer’s Disease Mechanisms via Integrated Multi-Omics and O-GlcNAc Profiling." The Team and The Project The project is led by Principal Investigators Dr. Priya Raman, PhD (NEOMED)

CADRC Neuroimaging Core Leader Dr. Mark Lowe and REC Scholar Dr. Benjamin Clayton present at the Spring 2026 NACC ADRC Meeting at the Loews Atlanta Hotel.

Celebrate Dr. Martha Sajatovic, CADRC Outreach Core Lead, recipient of the 2026 AAGP Distinguished Scientist Award for excellence in geriatric psychiatry research and mentorship.

YouTube video by Cleveland Alzheimer’s Disease Research Center

University Hospitals becomes the first host site for Howard University’s HU‑ERA‑PREP program. Meet Genesis Anderson, B.A., our newest coordinator helping to advance Alzheimer’s research and cultivate ...

The CADRC hosted its 2026 External Advisory Committee meeting to review research progress and strategic goals for Alzheimer’s and related dementia research.

New CADRC research led by Dr. Jagan Pillai identifies three distinct clinical subtypes in early-stage dementia by analyzing combined cognitive and behavioral symptoms.

A JAMA Neurology editorial by Dr. Brian Appleby and Dr. Mark Cohen evaluates claims of iatrogenic Alzheimer disease from historical growth hormone treatments, emphasizing that current medical practice...

What drives faster decline in dementia with Lewy bodies? New studies uncover key pathological and clinical factors, offering insights for better prognosis and clinical trial design.

The Cleveland Alzheimer’s Disease Research Center (CADRC) enhances its diagnostic capabilities with a new digital slide scanner. Learn how high-resolution digital imaging at the National Prion Disease...

Could CHCHD10 be the key to stopping Alzheimer’s? CADRC REC alumni Dr. Tian Liu launches NIA-funded research into tau aggregates and mitochondrial health.

Your Content Goes Here Your Content Goes Here CADRC REC Scholar Awarded Grant to Study Mixed Dementia Biomarkers We are pleased to announce that CADRC REC Scholar, Carol Chan, MD, has been awarded a 3-year Clinician Scientist Research Development Grant from the Cleveland Clinic Neurological Institute. Dr. Chan serves as a geriatric psychiatrist at the Cleveland Clinic Center for Brain Health and is an Assistant Professor at the Cleveland Clinic Lerner College of Medicine.

Your Content Goes Here Your Content Goes Here In Case You Missed It: CADRC Researchers Find that Alzheimer’s Disease Can Be Reversed in Animal Models A CADRC-led study challenges the belief that Alzheimer’s brain damage is permanent. Researchers restored cellular energy in animal models using a compound called P7C3-A20, which not only stopped disease progression but reversed existing brain damage and fully restored memory and cognitive function.

Your Content Goes Here Your Content Goes Here Driving Toward a Cure: A Heartfelt Thanks to Our Partners The Cleveland Alzheimer’s Disease Research Center (CADRC) is revving with gratitude! On Saturday, January 16, we celebrated a highly successful fundraising event brought to life by a fantastic partnership: Porsche Beachwood, the Northern Ohio Region Porsche Club of America (NORPCA), and WD Detailing.

In LBD, clumps of a protein called alpha-synuclein collect in several areas of the brain, such as:

Can moments of lucidity in Alzheimer’s reveal deeper insights into neurobiology? Our researchers are investigating cognitive fluctuations to improve diagnosis, monitoring and treatments. Learn about t...

In LBD, clumps of a protein called alpha-synuclein collect in several areas of the brain, such as: