‼️Preprint‼️ CD22 CAR Ts are cooked - time to move on to CD72. Adila Izgutdina and fantastic collaborators show CD72 is likely a better second-line antigen than CD22 for CD19-refractory B-ALL/B-NHL. Excited to bring CD72 “nanoCARs” to the clinic @ucsfhealth.bsky.social. www.biorxiv.org/content/10.1...
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies
Background: Chimeric antigen receptor (CAR) T-cell therapies are highly efficacious for several different hematologic cancers. However, for most CAR T targets it is observed that low surface antigen d...
www.biorxiv.org
May 16, 2025 at 4:17 PM
‼️Preprint‼️ CD22 CAR Ts are cooked - time to move on to CD72. Adila Izgutdina and fantastic collaborators show CD72 is likely a better second-line antigen than CD22 for CD19-refractory B-ALL/B-NHL. Excited to bring CD72 “nanoCARs” to the clinic @ucsfhealth.bsky.social. www.biorxiv.org/content/10.1...
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies https://www.biorxiv.org/content/10.1101/2025.05.09.653155v1
May 15, 2025 at 12:17 PM
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies https://www.biorxiv.org/content/10.1101/2025.05.09.653155v1
Cell-surface proteomic profiling identifies CD72 as a regulator of microglial tiling https://www.biorxiv.org/content/10.1101/2025.06.02.657480v1
June 6, 2025 at 3:15 AM
Cell-surface proteomic profiling identifies CD72 as a regulator of microglial tiling https://www.biorxiv.org/content/10.1101/2025.06.02.657480v1
A preprint using: APC anti-human CD72 (RRID:AB_2819948) from #BioLegend was published.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #OpenScience
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #OpenScience
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies
www.biorxiv.org
May 19, 2025 at 12:03 PM
A preprint using: APC anti-human CD72 (RRID:AB_2819948) from #BioLegend was published.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #OpenScience
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #OpenScience
Affinity-matured CD72-targeting nanobody CAR T-cells enhance elimination of antigen-low B-cell malignancies
www.biorxiv.org/content/10.1... @apwiita.bsky.social
www.biorxiv.org/content/10.1... @apwiita.bsky.social
May 16, 2025 at 1:53 AM
Affinity-matured CD72-targeting nanobody CAR T-cells enhance elimination of antigen-low B-cell malignancies
www.biorxiv.org/content/10.1... @apwiita.bsky.social
www.biorxiv.org/content/10.1... @apwiita.bsky.social
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies https://www.biorxiv.org/content/10.1101/2025.05.09.653155v1
May 15, 2025 at 12:17 PM
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies https://www.biorxiv.org/content/10.1101/2025.05.09.653155v1
With CD22-targeting CAR-T cells faltering, CD72 clearly stands out as the next big target. Proud to have contributed to Adila Izgutdina and amazing team’s preprint showing that our CD72 nanoCAR outperforms CD22 in CD19-refractory B-ALL and B-NHL. Excited for the Phase I trial at UCSF in 2026!
‼️Preprint‼️ CD22 CAR Ts are cooked - time to move on to CD72. Adila Izgutdina and fantastic collaborators show CD72 is likely a better second-line antigen than CD22 for CD19-refractory B-ALL/B-NHL. Excited to bring CD72 “nanoCARs” to the clinic @ucsfhealth.bsky.social. www.biorxiv.org/content/10.1...
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies
Background: Chimeric antigen receptor (CAR) T-cell therapies are highly efficacious for several different hematologic cancers. However, for most CAR T targets it is observed that low surface antigen d...
www.biorxiv.org
May 17, 2025 at 4:38 AM
With CD22-targeting CAR-T cells faltering, CD72 clearly stands out as the next big target. Proud to have contributed to Adila Izgutdina and amazing team’s preprint showing that our CD72 nanoCAR outperforms CD22 in CD19-refractory B-ALL and B-NHL. Excited for the Phase I trial at UCSF in 2026!
The authors included RRIDs in their in JCI Insight paper! RRIDs improve reproducibility in scientific research. #OpenResearch #BetterScience #STMpublishing
Deletion of 9p drives B-ALL through heterozygous inactivation of Pax5 and Cd72 in preleukemic cells
Read the full paper: Deletion of 9p drives B-ALL through heterozygous inactivation of Pax5 and Cd72 in preleukemic cells
doi.org
May 6, 2026 at 7:00 AM
The authors included RRIDs in their in JCI Insight paper! RRIDs improve reproducibility in scientific research. #OpenResearch #BetterScience #STMpublishing
Childhood B-ALL doesn’t start at diagnosis! In our new paper in JCI Insight, we show that a single genetic alteration in B-cell progenitors can create a stable pre-leukemic state. #Leukemia is a stepwise evolutionary process, and the earliest steps are already actionable biology.
JCI Insight -
Deletion 9p drives B-ALL through the heterozygous inactivation of Pax5 and Cd72 in pre-leukemic cells
insight.jci.org
February 18, 2026 at 11:13 AM
Childhood B-ALL doesn’t start at diagnosis! In our new paper in JCI Insight, we show that a single genetic alteration in B-cell progenitors can create a stable pre-leukemic state. #Leukemia is a stepwise evolutionary process, and the earliest steps are already actionable biology.
Via Cristoforo Colombo: 28enne accoltellato e ucciso dopo una lite. Sentiti i parenti
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
June 29, 2025 at 7:40 PM
Via Cristoforo Colombo: 28enne accoltellato e ucciso dopo una lite. Sentiti i parenti
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
Sanidad y Educación Pública, siempre.
Investigadores españoles describen una lesión genética que impulsa la leucemia linfoblástica aguda B
Un grupo de científicos ha demostrado cómo una deleción (un tipo de mutación) en el cromosoma 9, al inactivar parcialmente los genes PAX5 y CD72, desencadena el desarrollo de...
share.google
March 28, 2026 at 12:50 PM
Sanidad y Educación Pública, siempre.
Interesting dystopic/speculative fiction book which I enjoyed but didn't fully understand. Under the Eye of the Big Bird by Hiromi Kawakami.
app.thestorygraph.com/reviews/cd72...
app.thestorygraph.com/reviews/cd72...
Review by geraldinerowe - Under the Eye of the Big Bird
I've heard a lot of readers complain they didn't know what was going on until the last couple ...
app.thestorygraph.com
May 26, 2025 at 7:42 PM
Interesting dystopic/speculative fiction book which I enjoyed but didn't fully understand. Under the Eye of the Big Bird by Hiromi Kawakami.
app.thestorygraph.com/reviews/cd72...
app.thestorygraph.com/reviews/cd72...
John Lee Hooker — It Serve You Right to Suffer (1966)
https://musicbrainz.org/release/9ee51d0e-cd72-4446-9f73-f889b91c90c5
https://musicbrainz.org/release/9ee51d0e-cd72-4446-9f73-f889b91c90c5
September 19, 2026 at 4:02 PM
John Lee Hooker — It Serve You Right to Suffer (1966)
https://musicbrainz.org/release/9ee51d0e-cd72-4446-9f73-f889b91c90c5
https://musicbrainz.org/release/9ee51d0e-cd72-4446-9f73-f889b91c90c5
Via Cristoforo Colombo: 28enne accoltellato e ucciso dopo una lite. Sentiti i parenti
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
June 29, 2025 at 11:40 AM
Via Cristoforo Colombo: 28enne accoltellato e ucciso dopo una lite. Sentiti i parenti
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
http://roma.corriere.it/notizie/cronaca/25_giugno_29/uomo-ucciso-a-coltellate-in-via-cristoforo-colombo-a-roma-si-indaga-23bd12c5-cd72-4264-b492-37484f35cxlk.shtml
Deletion of 9p drives B-ALL through heterozygous inactivation of Pax5 and Cd72 in preleukemic cells: insight.jci.org/articles/vie...
April 16, 2026 at 11:02 AM
Deletion of 9p drives B-ALL through heterozygous inactivation of Pax5 and Cd72 in preleukemic cells: insight.jci.org/articles/vie...
The role of 9p deletion in B-ALL has been elusive since its discovery 40+ yrs ago
doi.org/10.1172/jci....
Here, Isidro Sánchez-García, @jmartcan.bsky.social & team combine genomic analyses & functional models to show that the co-deletion of Pax5 & Cd72 in mice drives oncogenesis
doi.org/10.1172/jci....
Here, Isidro Sánchez-García, @jmartcan.bsky.social & team combine genomic analyses & functional models to show that the co-deletion of Pax5 & Cd72 in mice drives oncogenesis
April 16, 2026 at 11:02 AM
The role of 9p deletion in B-ALL has been elusive since its discovery 40+ yrs ago
doi.org/10.1172/jci....
Here, Isidro Sánchez-García, @jmartcan.bsky.social & team combine genomic analyses & functional models to show that the co-deletion of Pax5 & Cd72 in mice drives oncogenesis
doi.org/10.1172/jci....
Here, Isidro Sánchez-García, @jmartcan.bsky.social & team combine genomic analyses & functional models to show that the co-deletion of Pax5 & Cd72 in mice drives oncogenesis
La Lazio riscatta il derby, a Genova vince 3-0
Cancellieri, Castellanos e Zaccagni siglano il trionfo...
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/29/la-lazio-riscatta-il-derby-a-genova-vince-3-0-_7230fe2b-cd72-4290-80d5-49009e39b188.html
Cancellieri, Castellanos e Zaccagni siglano il trionfo...
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/29/la-lazio-riscatta-il-derby-a-genova-vince-3-0-_7230fe2b-cd72-4290-80d5-49009e39b188.html
September 29, 2025 at 8:55 PM
La Lazio riscatta il derby, a Genova vince 3-0
Cancellieri, Castellanos e Zaccagni siglano il trionfo...
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/29/la-lazio-riscatta-il-derby-a-genova-vince-3-0-_7230fe2b-cd72-4290-80d5-49009e39b188.html
Cancellieri, Castellanos e Zaccagni siglano il trionfo...
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/29/la-lazio-riscatta-il-derby-a-genova-vince-3-0-_7230fe2b-cd72-4290-80d5-49009e39b188.html
Serie A: in campo Genoa-Lazio 0-2 DIRETTA e FOTO
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
September 29, 2025 at 7:25 PM
Serie A: in campo Genoa-Lazio 0-2 DIRETTA e FOTO
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Serie A: in campo Genoa-Lazio 0-1 DIRETTA e FOTO
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
September 29, 2025 at 7:10 PM
Serie A: in campo Genoa-Lazio 0-1 DIRETTA e FOTO
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Serie A: in campo Genoa-Lazio
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
September 29, 2025 at 6:55 PM
Serie A: in campo Genoa-Lazio
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Diretta e foto
https://www.ansa.it/sito/notizie/sport/calcio/2025/09/26/serie-a-in-campo-lunedi-alle-2045-genoa-lazio_7230fe2b-cd72-4290-80d5-49009e39b188.html
Cell-surface proteomic profiling identifies CD72 as a regulator of microglial tiling #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.06.02.657480v1
https://www.biorxiv.org/content/10.1101/2025.06.02.657480v1
June 6, 2025 at 7:01 AM
Cell-surface proteomic profiling identifies CD72 as a regulator of microglial tiling #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.06.02.657480v1
https://www.biorxiv.org/content/10.1101/2025.06.02.657480v1
December 8, 2025 at 12:59 PM
August 2, 2025 at 10:37 PM
February 6, 2025 at 8:07 PM
December 22, 2024 at 7:34 AM