#CPUG
⋆✴︎˚。⋆𝗘𝘀𝗰𝗿𝗲𝘃𝗲𝗻𝗱𝗼 𝐂𝐏𝐔𝐆
⭑.ᐟ 𝗔 𝘁𝗵𝗿𝗲𝗮𝗱
April 7, 2026 at 9:31 PM
Now we just need to overhaul CPUG so it actually helps us instead of actively undermining us.
March 31, 2026 at 6:13 AM
Strikingly, CPUG resembles the cleavage and polyadenylation (CPA) complex: both pair an active nuclease with an inactive paralog and a nucleotidyltransferase, activating cleavage only after assembly. A similar architectural strategy for very different problems and very different RNA fates.
September 8, 2026 at 8:25 PM
The Essential Role of Branding for Small Businesses: Insights from CPUG's 33 Years of Experience#Japan#Tokyo#Branding#Small_Business#CPUG
The Essential Role of Branding for Small Businesses: Insights from CPUG's 33 Years of Experience
Discover how small businesses can leverage branding to enhance their corporate identity. CPUG reveals their branding methodology honed over 33 years.
third-news.com
July 14, 2026 at 11:47 AM
📢 PENSIONI: ATTACCO SENZA PRECEDENTI AI DIPENDENTI PUBBLICI

Per la prima volta, neppure con la Legge Monti-Fornero, si toccano le posizioni contributive già maturate.

www.cgil.it/ufficio-stam...
Pensioni: attacco senza precedenti contro lavoratrici e lavoratori pubblici
Scopri gli effetti del taglio alle aliquote di rendimento introdotto dalla Legge di Bilancio 2024. Tabelle e simulazioni INPS 2025 per dipendenti pubblici (CPDEL, CPS, CPI, CPUG).
www.cgil.it
August 30, 2025 at 7:33 AM
Remember this ? www.youtube.com/watch?v=cpuG... Maybe Orange Shitler will just fly away ! We can dream !
Marbles found - clip from Hook
YouTube video by Rick Upchurch
www.youtube.com
May 16, 2025 at 11:50 PM
By exploring the trends in observed and simulated urban surface temperatures, we quantified the cooling potential of urban greening of 0.20 K over the past two decades, which slowed down the warming trend by 14.17% in Chinese cities.
pubs.acs.org/doi/10.1021/...
Quantifying the Cooling Effect of Urban Greening Driven by Ecological Restoration Projects in China
Urban greening (UG) affects local climate by altering surface energy balance, while long-term UG cooling potential, patterns, and contribution to curbing urban warming remain unclear. Here, we designed an novel statistical model to evaluate the cooling potential of UG (CPUG) and created the first CPUG map for China. By exploring the trends in observed and simulated urban surface temperatures (UST), we quantified the CPUG of 0.20 K over the past two decades, which slowed down the warming trend by 14.17% in Chinese cities. We found that the CPUG varied significantly between the urban core and sprawl areas. Specifically, the CPUG in the urban core was approximately 1.01 K, and it contributed to curbing urban warming by 56.08%, which was more than 7.2 times higher than in the sprawl areas, where the CPUG was only 0.14 K and contributed to curbing urban warming by 9.93%. We further revealed that urbanization and major ecological restoration projects are the key factors influencing CPUG, emphasizing the need for anthropogenic vegetation management to curb urban warming. The proposed model in this study provides a powerful tool for quantitatively assessing the impact of long-term UG trends on urban warming. The results of the study are an important reference for building climate-adaptive cities.
pubs.acs.org
November 22, 2024 at 7:46 PM
Finally, how does CPUG ensure directionality and protect the RNA from re-cleavage? Two ways: RNA engagement by MUT-2 limits RDE-8 access, and RDE-8 sequence preference spares the new poly(UG) tail. Together, these features keep the reaction moving forward.
September 8, 2026 at 8:25 PM
RNA cleavage is irreversible and potentially dangerous, so RDE-8 -the endoribonuclease of CPUG- must be tightly controlled. We found that RDE-8 forms an autoinhibited heterodimer with the pseudonuclease NYN-1, keeping cleavage restrained until CPUG assembles.
September 8, 2026 at 8:25 PM
Celebrating 33 Years: Introducing CPUG's Branding Starter Kit for SMEs#Japan#SMEs#Chuo,_Tokyo#CPUG#Branding_Kit
Celebrating 33 Years: Introducing CPUG's Branding Starter Kit for SMEs
In honor of its 33rd anniversary, CPUG launches a special branding package for SMEs, priced at 330,000 yen for the first 33 companies.
third-news.com
July 13, 2026 at 10:04 AM
Pensioni, l’Inps sbaglia i calcoli del taglio 2024: ecco i rimborsi
Pensioni, l'Inps sbaglia i calcoli del taglio 2024: ecco i rimborsi
È il secondo errore dopo quello dei mille euro dati a 20 mila pensionati. Ora la correzione sulla norme per gli iscritti alle casse Cpdel, Cps, Cpi e Cpug
www.open.online
April 7, 2026 at 6:09 AM
After cleavage, MUT-2 -the remarkable CPUG nucleotidyltransferase- adds long, alternating poly(UG) tails. Using high-throughput sequencing, we found that the RNA 3′ end influences both tailing efficiency and the register of the UG repeat.
September 8, 2026 at 8:25 PM
At the center of CPUG is MUT-15, which connects the RDE-8/NYN-1 nuclease module to the poly(UG) polymerase MUT-2. MUT-15 has the two RecA-like domains characteristic of DEAD-box helicases but lacks ATPase activity: it is a pseudohelicase!
September 8, 2026 at 8:25 PM
In C. elegans, RNA cleavage and poly(UG)ylation mark Argonaute-targeted transcripts as templates for secondary small-RNA production, enabling efficient and robust RNAi. We biochemically reconstituted the machinery responsible: the cleavage and poly(UG)ylation (CPUG) complex.
September 8, 2026 at 8:25 PM
Il Governo interviene retroattivamente, tagliando la quota retributiva delle pensioni per chi ha meno di 15 anni di contributi al 31/12/1995.

Una misura che colpisce migliaia di lavoratrici e lavoratori iscritti a CPDEL, CPS, CPI e CPUG.
August 30, 2025 at 7:33 AM
#TechRadar NYT Strands hints and answers for Wednesday, April 1 (game #759) https://techrad.ar/CPUg #Websites&Apps #Computing #Internet
March 31, 2026 at 11:35 PM
Ex casse statali: deroghe alle nuove aliquote per la pensione
![CDATA[ L’Inps con il messaggio del 25 agosto 2025 n. 2491 ha individuato ulteriori casi di esonero dalle nuove aliquote di rendimento, applicabili ai dipendenti iscritti alla Cassa per le pensioni ai dipendenti degli enti locali (CPDEL), alla Cassa per le pensioni ai sanitari (CPS), alla Cassa per le pensioni agli insegnanti di asilo e di scuole elementari parificate (CPI) e alla Cassa per le pensioni agli ufficiali giudiziari, agli aiutanti ufficiali giudiziari e ai coadiutori (CPUG).A seguito dell’innalzamento dell’età ordinamentale dei dipendenti pubblici da 65 a 67 anni da parte della legge di bilancio, dal 2025 tali aliquote, secondo la legge medesima, non trovano applicazione nei casi di cessazione dal servizio per raggiungimento dei limiti di età o di servizio previsti dagli ordinamenti di appartenenza.Ciò detto, per il nuovo messaggio emanato dall’Inps, le nuove aliquote di rendimento non trovano applicazione inoltre: -       per la liquidazione della pensione di vecchiaia nei confronti dei dipendenti di datori di lavoro che hanno perso la natura giuridica pubblica e che hanno mantenuto l’iscrizione alla CPDEL; -       per la pensione di vecchiaia in cumulo quando l’interessato, all’atto della risoluzione del rapporto di lavoro alle dipendenze di una pubblica Amministrazione per limiti ordinamentali, risulti iscritto al Fondo pensioni lavoratori dipendenti dell’Assicurazione generale obbligatoria; -       quando il dipendente si dimetta prima dello scadere del periodo di trattenimento in servizio ma dopo il raggiungimento del limite ordinamentale; -       in caso di raggiungimento del diritto a pensione di vecchiaia, subito dopo la liquidazione dell’anticipo pensionistico dell’Ape sociale anche in cumulo con altri ordinamenti previdenziali, -       nei casi di maturazione della pensione anticipata ai precoci (41 anni di contribuzione) entro il 31 dicembre 2023.]]
dlvr.it
August 27, 2025 at 10:03 PM
Kindergarten with Laenz, Sobolik b2b Drummy b2b Martini @TheLotRadio 04-05-2025 now available for replay! https://www.youtube.com/watch?v=cPUG-_iG3zo
www.youtube.com
April 7, 2025 at 4:28 AM
Wait this is familiar; another friend posted about this earlier: bsky.app/profile/cpug...
Apparently the Capitol Hill Starbucks Reserve Roastery has suddenly permanently closed.
This was a flagship location, always *packed*, lines out the door. Paying the extra high prices that this store brings.

The employees at this store, last I saw, were attempting to unionize.
September 28, 2025 at 7:00 AM
Allungamento delle finestre di uscita
La Legge di Bilancio 2024 ha previsto un incremento delle finestre di uscita per i lavoratori iscritti a CPDEL, CPS, CPI e CPUG.

Dal 2025, chi accede alla pensione anticipata dovrà attendere fino a 9 mesi in più rispetto alle regole precedenti.
August 30, 2025 at 7:33 AM