Me: What's CRISPR's favorite 90's song?
Also me: Splice, Splice Baby.
My family: wut.
Also me: Splice, Splice Baby.
My family: wut.
August 23, 2025 at 12:38 PM
Me: What's CRISPR's favorite 90's song?
Also me: Splice, Splice Baby.
My family: wut.
Also me: Splice, Splice Baby.
My family: wut.
We went looking for CRISPR’s roots. A structure-guided search uncovered a phage-encoded family of RAMP-like proteins. Phylogeny suggests VIPR predates Cas5-7.
April 27, 2026 at 9:32 PM
We went looking for CRISPR’s roots. A structure-guided search uncovered a phage-encoded family of RAMP-like proteins. Phylogeny suggests VIPR predates Cas5-7.
VIPR is now out in Science!
What started with a mysterious RNA led us to an unexpected way of recognizing DNA, as well as some clues to CRISPR’s origins.
So happy to share these two papers with an incredible team. Links below; original discovery thread here ↓
What started with a mysterious RNA led us to an unexpected way of recognizing DNA, as well as some clues to CRISPR’s origins.
So happy to share these two papers with an incredible team. Links below; original discovery thread here ↓
Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR.
We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets.
Thread + link below.
We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets.
Thread + link below.
September 18, 2026 at 4:38 PM
VIPR is now out in Science!
What started with a mysterious RNA led us to an unexpected way of recognizing DNA, as well as some clues to CRISPR’s origins.
So happy to share these two papers with an incredible team. Links below; original discovery thread here ↓
What started with a mysterious RNA led us to an unexpected way of recognizing DNA, as well as some clues to CRISPR’s origins.
So happy to share these two papers with an incredible team. Links below; original discovery thread here ↓
Jimi Olaghere has lived with sickle cell disease his whole life—experiencing chronic pain, organ damage, and hopelessness. As a patient enrolled in a clinical trial for Vertex’s new exa-cel treatment, he was among the first to experience CRISPR’s transformative effects. It changed his life.
I received the new gene-editing drug for sickle cell disease. It changed my life.
As a patient enrolled in a clinical trial for Vertex’s new exa-cel treatment, I was among the first to experience CRISPR’s transformative effects.
www.technologyreview.com
December 4, 2023 at 6:41 PM
Jimi Olaghere has lived with sickle cell disease his whole life—experiencing chronic pain, organ damage, and hopelessness. As a patient enrolled in a clinical trial for Vertex’s new exa-cel treatment, he was among the first to experience CRISPR’s transformative effects. It changed his life.
Gene Editing Has Struggled To Go Commercial. This Nobel Laureate Has A $1 Billion Plan To Fix That.
Jennifer Doudna’s $1 Billion Plan To Bring Gene Editing To The Masses
Crispr’s ability to cut genetic code like scissors has just started to turn into medicines. Now, gene editing pioneer Jennifer Doudna wants to build an entire ecosystem to bring these treatments mains...
www.forbes.com
February 17, 2026 at 8:57 PM
Gene Editing Has Struggled To Go Commercial. This Nobel Laureate Has A $1 Billion Plan To Fix That.
A monumental milestone in medicine: using CRISPR gene-editing technology to remove HIV DNA from infected human cells permanently.
CRISPR’s precision allows it to selectively remove harmful sequences without damaging healthy DNA, a feat that opens doors for treating other genetic diseases as well ✨
CRISPR’s precision allows it to selectively remove harmful sequences without damaging healthy DNA, a feat that opens doors for treating other genetic diseases as well ✨
October 1, 2025 at 7:17 PM
A monumental milestone in medicine: using CRISPR gene-editing technology to remove HIV DNA from infected human cells permanently.
CRISPR’s precision allows it to selectively remove harmful sequences without damaging healthy DNA, a feat that opens doors for treating other genetic diseases as well ✨
CRISPR’s precision allows it to selectively remove harmful sequences without damaging healthy DNA, a feat that opens doors for treating other genetic diseases as well ✨
I give the whole Dire Wolf thing shit, but this is absolutely right. CRISPR's a fucking game changer.
I just wish there was just less money in trying to convince us we can bring back mammoths (we can't) and more in ways to solve actual problems (which some are!)
I just wish there was just less money in trying to convince us we can bring back mammoths (we can't) and more in ways to solve actual problems (which some are!)
Y’all are upset at the marketing, which I completely understand. Not defending the marketing here, it’s ridiculous
But the other way to look at it is that they CRISPR’d a puppy dog to make 20 genetic modifications which is pretty incredible
But the other way to look at it is that they CRISPR’d a puppy dog to make 20 genetic modifications which is pretty incredible
To put things into perspective
FAKE DIRE WOLF
25 years for CRISPR development
3 years for DNA collection
1 year for gene editing and breeding
$435M raised in venture capital
LABRADOODLE
40 million years of evolution
2 horny dogs
FAKE DIRE WOLF
25 years for CRISPR development
3 years for DNA collection
1 year for gene editing and breeding
$435M raised in venture capital
LABRADOODLE
40 million years of evolution
2 horny dogs
April 8, 2025 at 4:59 PM
I give the whole Dire Wolf thing shit, but this is absolutely right. CRISPR's a fucking game changer.
I just wish there was just less money in trying to convince us we can bring back mammoths (we can't) and more in ways to solve actual problems (which some are!)
I just wish there was just less money in trying to convince us we can bring back mammoths (we can't) and more in ways to solve actual problems (which some are!)
“The best that I can do in terms of making the next breakthrough or discovery is not to do it by myself, but to enable other scientists to do it”
— Jennifer Doudna
www.forbes.com/sites/amyfel...
— Jennifer Doudna
www.forbes.com/sites/amyfel...
Jennifer Doudna’s $1 Billion Plan To Bring Gene Editing To The Masses
Crispr’s ability to cut genetic code like scissors has just started to turn into medicines. Now, gene editing pioneer Jennifer Doudna wants to build an entire ecosystem to bring these treatments mains...
www.forbes.com
February 18, 2026 at 6:16 PM
“The best that I can do in terms of making the next breakthrough or discovery is not to do it by myself, but to enable other scientists to do it”
— Jennifer Doudna
www.forbes.com/sites/amyfel...
— Jennifer Doudna
www.forbes.com/sites/amyfel...
Brilliant.
Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study, published in Advanced Science, highlights CRISPR's potential for cancer treatment
www.technologynetworks.com/genomics/new....
Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study, published in Advanced Science, highlights CRISPR's potential for cancer treatment
www.technologynetworks.com/genomics/new....
CRISPR Therapy Eliminates 50% of Head and Neck Tumors
Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study highlights CRISPR’s potential for cancer treatment.
www.technologynetworks.com
March 12, 2025 at 3:03 AM
Brilliant.
Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study, published in Advanced Science, highlights CRISPR's potential for cancer treatment
www.technologynetworks.com/genomics/new....
Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study, published in Advanced Science, highlights CRISPR's potential for cancer treatment
www.technologynetworks.com/genomics/new....
CRISPR’s next act: the companies editing the epigenome to treat disease www.nature.com/articles/d41...
CRISPR’s next act: the companies editing the epigenome to treat disease
A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
www.nature.com
June 29, 2026 at 5:46 PM
CRISPR’s next act: the companies editing the epigenome to treat disease www.nature.com/articles/d41...
MIT researchers have re-engineered CRISPR’s “prime editors” to slash one of their biggest problems: random DNA errors. The result is a new family of editors that keep efficiency while cutting indel errors up to 60-fold. buff.ly/5zaa88B
#ShareGoodNewsToo
#ShareGoodNewsToo
Engineered prime editors with minimal genomic errors - Nature
Engineered prime editor systems with reduced occurrences of unwanted insertions or deletions during genome editing are developed.
buff.ly
October 7, 2025 at 12:50 PM
MIT researchers have re-engineered CRISPR’s “prime editors” to slash one of their biggest problems: random DNA errors. The result is a new family of editors that keep efficiency while cutting indel errors up to 60-fold. buff.ly/5zaa88B
#ShareGoodNewsToo
#ShareGoodNewsToo
Most epigenetic-editing platforms, rather than making changes to the DNA itself, modify the markers attached to DNA
go.nature.com/4vEIxQg
go.nature.com/4vEIxQg
CRISPR’s next act: the companies editing the epigenome to treat disease
Nature - A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
go.nature.com
July 4, 2026 at 9:32 AM
Most epigenetic-editing platforms, rather than making changes to the DNA itself, modify the markers attached to DNA
go.nature.com/4vEIxQg
go.nature.com/4vEIxQg
This sounds great! We are planning a similar event for high school teachers @cibss.bsky.social - highlighting CRISPR's potential in medicine and plant breeding! Would be very interesting to hear about your experience!
July 9, 2025 at 6:56 PM
This sounds great! We are planning a similar event for high school teachers @cibss.bsky.social - highlighting CRISPR's potential in medicine and plant breeding! Would be very interesting to hear about your experience!
A feature in Nature reports how a handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder. 🧬🧪
CRISPR’s next act: the companies editing the epigenome to treat disease
A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
go.nature.com
July 8, 2026 at 1:44 AM
A feature in Nature reports how a handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder. 🧬🧪
CRISPR's efficiency triples in lab tests with DNA-wrapped nanoparticles phys.org/news/2025-08... via @physorg_com
CRISPR's efficiency triples in lab tests with DNA-wrapped nanoparticles
With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine. But until scientists can deliver its gene-editing machinery safely and...
phys.org
September 3, 2025 at 1:25 AM
CRISPR's efficiency triples in lab tests with DNA-wrapped nanoparticles phys.org/news/2025-08... via @physorg_com
Most epigenetic-editing platforms, rather than making changes to the DNA itself, modify the markers attached to DNA
go.nature.com/4oUUHC1
go.nature.com/4oUUHC1
CRISPR’s next act: the companies editing the epigenome to treat disease
Nature - A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
go.nature.com
June 30, 2026 at 12:47 PM
Most epigenetic-editing platforms, rather than making changes to the DNA itself, modify the markers attached to DNA
go.nature.com/4oUUHC1
go.nature.com/4oUUHC1
Did you know that CRISPR's fascinating story started in a small lab in Spain in 1993? Francisco Mojica discovered CRISPR while studying a bacteria commonly used to produce mozzarella and yogurt.
If you want to learn more about CRISPR's fast journey from bench to bedside, check out this Timeline!
If you want to learn more about CRISPR's fast journey from bench to bedside, check out this Timeline!
April 16, 2025 at 1:44 PM
Did you know that CRISPR's fascinating story started in a small lab in Spain in 1993? Francisco Mojica discovered CRISPR while studying a bacteria commonly used to produce mozzarella and yogurt.
If you want to learn more about CRISPR's fast journey from bench to bedside, check out this Timeline!
If you want to learn more about CRISPR's fast journey from bench to bedside, check out this Timeline!
Most epigenetic-editing platforms, rather than making changes to the DNA itself, modify the markers attached to DNA
go.nature.com/4oMVuF4
go.nature.com/4oMVuF4
CRISPR’s next act: the companies editing the epigenome to treat disease
A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
go.nature.com
June 26, 2026 at 3:16 PM
Most epigenetic-editing platforms, rather than making changes to the DNA itself, modify the markers attached to DNA
go.nature.com/4oMVuF4
go.nature.com/4oMVuF4
A feature in Nature reports how a handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder. 🧬🧪
CRISPR’s next act: the companies editing the epigenome to treat disease
A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
go.nature.com
July 1, 2026 at 4:51 PM
A feature in Nature reports how a handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder. 🧬🧪
I wonder if, ironically, this dedicated, hyper-complicated, out-of-the-limelight application of the science of gene editing turns out to be CRISPR's killer app.
(The debate may commence below.)
5/5
(The debate may commence below.)
5/5
February 8, 2025 at 2:30 PM
I wonder if, ironically, this dedicated, hyper-complicated, out-of-the-limelight application of the science of gene editing turns out to be CRISPR's killer app.
(The debate may commence below.)
5/5
(The debate may commence below.)
5/5
· #Bioscience · #GenomeEditing · #CRISPR · #SciSky · #SciComm ·
CRISPR’s next act: the companies editing the epigenome to treat disease
CRISPR’s next act: the companies editing the epigenome to treat disease
CRISPR’s next act: the companies editing the epigenome to treat disease
A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
www.nature.com
June 29, 2026 at 11:04 AM
· #Bioscience · #GenomeEditing · #CRISPR · #SciSky · #SciComm ·
CRISPR’s next act: the companies editing the epigenome to treat disease
CRISPR’s next act: the companies editing the epigenome to treat disease
NEW for @forbes.com: Nobel Prize winner Jennifer Doudna’s plan to create a gene editing ecosystem to solve major problems in medicine, agriculture and climate.
“I don’t want it to be a curio, a topic of academic interest,” she says.
www.forbes.com/sites/amyfel...
“I don’t want it to be a curio, a topic of academic interest,” she says.
www.forbes.com/sites/amyfel...
Jennifer Doudna’s $1 Billion Plan To Bring Gene Editing To The Masses
Crispr’s ability to cut genetic code like scissors has just started to turn into medicines. Now, gene editing pioneer Jennifer Doudna wants to build an entire ecosystem to bring these treatments mains...
www.forbes.com
February 17, 2026 at 1:50 PM
NEW for @forbes.com: Nobel Prize winner Jennifer Doudna’s plan to create a gene editing ecosystem to solve major problems in medicine, agriculture and climate.
“I don’t want it to be a curio, a topic of academic interest,” she says.
www.forbes.com/sites/amyfel...
“I don’t want it to be a curio, a topic of academic interest,” she says.
www.forbes.com/sites/amyfel...
エピゲノム編集による疾患治療を狙うスタートアップ
CRISPR’s next act: the companies editing the epigenome to treat disease www.nature.com/articles/d41...
CRISPR’s next act: the companies editing the epigenome to treat disease www.nature.com/articles/d41...
CRISPR’s next act: the companies editing the epigenome to treat disease
A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder.
www.nature.com
June 30, 2026 at 3:12 AM
エピゲノム編集による疾患治療を狙うスタートアップ
CRISPR’s next act: the companies editing the epigenome to treat disease www.nature.com/articles/d41...
CRISPR’s next act: the companies editing the epigenome to treat disease www.nature.com/articles/d41...
CRISPR's a funny one because it's always brought up but it was developed in 2012-2013, right before the start of the technological wasteland
October 16, 2023 at 8:38 AM
CRISPR's a funny one because it's always brought up but it was developed in 2012-2013, right before the start of the technological wasteland
Uzaktan kontrollü gen terapisi kanseri ultrasonla öldürüyor.
Kanser hücrelerine saldırmak için ultrason darbeleri kullanan CRISPR👇
viterbischool.usc.edu/news/2024/12...
Kanser hücrelerine saldırmak için ultrason darbeleri kullanan CRISPR👇
viterbischool.usc.edu/news/2024/12...
New CRISPR Toolkit to Allow Remote-Controlled Genome Editing - USC Viterbi | School of Engineering
USC Viterbi biomedical engineers harness focused ultrasound to revolutionize CRISPR's capabilities to treat countless diseases.
viterbischool.usc.edu
December 9, 2024 at 12:57 PM
Uzaktan kontrollü gen terapisi kanseri ultrasonla öldürüyor.
Kanser hücrelerine saldırmak için ultrason darbeleri kullanan CRISPR👇
viterbischool.usc.edu/news/2024/12...
Kanser hücrelerine saldırmak için ultrason darbeleri kullanan CRISPR👇
viterbischool.usc.edu/news/2024/12...