#Calbicans
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plosbiology.org
#Candida albicans is a leading opportunistic fungal #pathogen of humans. Ci Fu, Leah Cowen &co expand the GRACE #Calbicans #FunctionalGenomics resource, identifying genes important for temperature-dependent fitness & highlighting its power to reveal vulnerabilities @plosbiology.org 🧪 plos.io/3Wft0Xg
Screening of expanded GRACE mutant collection at six temperatures reveals distinct functional enrichment in genes clustered by fitness profile. Top left: Schematic of GRACE mutant construction. Bottom left: Summary of GRACE mutant collection expansion based on manual curation of biological process gene ontology annotation on Candida Genome Database (CGD). Pie chart with four concentric rings visualizes the relative proportion of genes from various versions of the GRACE collection with biological process descriptions completely unannotated or annotated based on: experimentally characterization, S. cerevisiae ortholog, S. pombe ortholog, orthologs in other fungal species, conserved protein domains, or unannotated; see Materials and methods for full details. Right: Heatmap of genes ordered by hierarchical clustering of essentiality scores across screening temperatures. A score of 4 (red) represents no growth and 0 (yellow) represents growth comparable to wild type.
October 20, 2025 at 7:46 AM
normanvanrhijn.bsky.social
Nice! RFP Calbicans?
October 18, 2023 at 9:46 AM
plosbiology.org
#Candida albicans is a leading opportunistic fungal #pathogen of humans. Ci Fu, Leah Cowen &co expand the GRACE #Calbicans #FunctionalGenomics resource, identifying genes important for temperature-dependent fitness & highlighting its power to reveal vulnerabilities @plosbiology.org 🧪 plos.io/3Wft0Xg
Screening of expanded GRACE mutant collection at six temperatures reveals distinct functional enrichment in genes clustered by fitness profile. Top left: Schematic of GRACE mutant construction. Bottom left: Summary of GRACE mutant collection expansion based on manual curation of biological process gene ontology annotation on Candida Genome Database (CGD). Pie chart with four concentric rings visualizes the relative proportion of genes from various versions of the GRACE collection with biological process descriptions completely unannotated or annotated based on: experimentally characterization, S. cerevisiae ortholog, S. pombe ortholog, orthologs in other fungal species, conserved protein domains, or unannotated; see Materials and methods for full details. Right: Heatmap of genes ordered by hierarchical clustering of essentiality scores across screening temperatures. A score of 4 (red) represents no growth and 0 (yellow) represents growth comparable to wild type.
October 20, 2025 at 5:11 PM
plosbiology.org
#Candida albicans is a leading opportunistic fungal #pathogen of humans. Ci Fu, Leah Cowen &co expand the GRACE #Calbicans #FunctionalGenomics resource, identifying genes important for temperature-dependent fitness & highlighting its power to reveal vulnerabilities @plosbiology.org 🧪 plos.io/3Wft0Xg
Screening of expanded GRACE mutant collection at six temperatures reveals distinct functional enrichment in genes clustered by fitness profile. Top left: Schematic of GRACE mutant construction. Bottom left: Summary of GRACE mutant collection expansion based on manual curation of biological process gene ontology annotation on Candida Genome Database (CGD). Pie chart with four concentric rings visualizes the relative proportion of genes from various versions of the GRACE collection with biological process descriptions completely unannotated or annotated based on: experimentally characterization, S. cerevisiae ortholog, S. pombe ortholog, orthologs in other fungal species, conserved protein domains, or unannotated; see Materials and methods for full details. Right: Heatmap of genes ordered by hierarchical clustering of essentiality scores across screening temperatures. A score of 4 (red) represents no growth and 0 (yellow) represents growth comparable to wild type.
October 20, 2025 at 12:55 PM
marcrescente.bsky.social
Very honoured to have received the award for the best offered talk about platelet-driven neutrophil anti-C.albicans immunity #BSMM25 #Norwich2025 #platelets #NETs #Calbicans
September 9, 2025 at 2:43 PM
normanvanrhijn.bsky.social
Any chance you would be willing to share? Been looking for red Calbicans for forever
October 18, 2023 at 10:17 AM
bcmfromthelabs.bsky.social
Dr. D Corry, K Mauk et al have discovered unexpected factors that help #Calbicans settle and persist in the #gut.
#JournalSpectrum @bcmhouston.bsky.social #BCMDeptMedicine #MedicalIndustryToday www.medicalindustrytoday.com/article/8433...
August 27, 2025 at 3:27 PM
bcmfromthelabs.bsky.social
Dr. D Corry, K. Mauk et al uncovered this common fungus's strategy to colonize the gut. @bcmhouston.bsky.social www.bcm.edu/news/how-the... #Calbicans
How the common fungus Candida albicans colonizes the gut
About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years causing no health problems,...
www.bcm.edu
July 30, 2025 at 5:16 PM