#CalciumReleaseDeficiencySyndrome
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jamacardiology.com
A novel provocation test clinically diagnosed #CalciumReleaseDeficiencySyndrome in a family with unexplained sudden cardiac arrest and death, with pause-dependent T-wave changes supporting CRDS risk stratification.

ja.ma/4e3pHKZ
Figure 2: Functional impact & 3D location of RYR2-Glu336Gly. Panel A graphs caffeine response, showing RYR2-Glu336Gly has higher peak Ca2+ release than RYR2-WT at lower concentrations. Panel B displays the 3D protein structure, highlighting the Glu336Gly variant's position.
June 5, 2026 at 11:00 AM
jamacardiology.com
A novel provocation test clinically diagnosed #CalciumReleaseDeficiencySyndrome in a family with unexplained sudden cardiac arrest and death, with pause-dependent T-wave changes supporting CRDS risk stratification.

ja.ma/4ovJzLz
Figure 2: Functional impact & 3D location of RYR2-Glu336Gly. Panel A graphs caffeine response, showing RYR2-Glu336Gly has higher peak Ca2+ release than RYR2-WT at lower concentrations. Panel B displays the 3D protein structure, highlighting the Glu336Gly variant's position.
June 16, 2026 at 12:00 PM
jamacardiology.com
A novel provocation test clinically diagnosed #CalciumReleaseDeficiencySyndrome in a family with unexplained sudden cardiac arrest and death, with pause-dependent T-wave changes supporting CRDS risk stratification.

ja.ma/4xdO6Gv
Figure 2: Functional impact & 3D location of RYR2-Glu336Gly. Panel A graphs caffeine response, showing RYR2-Glu336Gly has higher peak Ca2+ release than RYR2-WT at lower concentrations. Panel B displays the 3D protein structure, highlighting the Glu336Gly variant's position.
June 7, 2026 at 11:00 AM
jamacardiology.com
A novel provocation test clinically diagnosed #CalciumReleaseDeficiencySyndrome in a family with unexplained sudden cardiac arrest and death, with pause-dependent T-wave changes supporting CRDS risk stratification. ja.ma/437hGzK
Clinical Diagnosis of Calcium Release Deficiency Syndrome in a Family With Sudden Cardiac Death
This case series explores how the novel calcium release deficiency syndrome provocation test can clinically establish the diagnosis in a family with unexplained sudden cardiac arrest and death.
ja.ma
June 3, 2026 at 2:00 PM