Harold Varmus, 1982 Lasker Laureate, discusses the role of intuition in research.

Douglas Lowy and John Schiller are honored for technological advances that enabled development of HPV vaccines for prevention of cervical cancer and other tumors caused by human papillomaviruses.

Cell biologist Craig Thompson discusses strategies to communicate with patients.

Rohini discusses how ketogenic nutrition may complement specific cancer therapies and help address cancer-related weight and muscle loss.

Engineered T cells, reprogrammed to express chimeric antigen receptors (CAR) or T cell receptors (TCR), have transformed cancer treatment and are being explored as therapeutics for autoimmune and infectious diseases. Enhancing T cell function through genome editing, either by disrupting endogenous genes or precisely inserting DNA payloads, has shown considerable promise1. However, the ex vivo manufacturing process is lengthy and costly, limiting accessibility of these therapies. In vivo generation of CAR T cells could overcome these barriers, but current methods rely either on...

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat “triple ne...