Human disease-relevant mutations in the VRK-1 basic-acidic-basic patch result in motor impairment independent of mitotic defects in C. elegans #micropublication #biology #data #caltechlibrary #Celegan https://micropublication.org/journals/biology/micropub-biology-002279

Neurons of a #Celegan reveal how tau — a protein that usually stabilizes brain cells — can go rogue in #Alzheimers. When tau detaches and clumps together, it disrupts neuron communication and contributes to cognitive decline.

#standwithscience #researchmatters #microscopymonday #lightsheet 🧪 🤝