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haoyin.bsky.social
Polyploidy & mTOR signaling: a possible molecular link

Cancer
Diabetes
Aging

Can polyploidy be a unique drug target? 🧐

#CellCommunSignal 2024
biosignaling.biomedcentral.com/articles/10....
July 26, 2025 at 11:54 AM
haoyin.bsky.social
How BMP9/10 induces Endothelial Cell Quiescence?

#Phosphoproteome HUVEC+BMP9/10
>3k phosphoproteins (289 DpP)
>12k phosphosites (419 DpPs)

Cell cycle kinases inferred
CDK4/6⬇️
CDC7⬇️
PLK3⬇️(BMP9 only)
CHK1⬆️

#CellCommunSignal 2024
link.springer.com/article/10.1...
June 2, 2026 at 11:39 AM
realbiomassspec.bsky.social
Clinical features, plasma neurotransmitter levels and plasma neurohormone levels among patients with early-stage Parkinson's disease with sleep disorders #CellCommunSignal #MassSpec biosignaling.biomedcentral.com/articles/10....
Clinical features, plasma neurotransmitter levels and plasma neurohormone levels among patients with early-stage Parkinson’s disease with sleep disorders - Cell Communication and Signaling
Background Sleep disorders occur frequently among patients with Parkinson’s disease (PD). Neurotransmitters and neurosteroids are known to be involved in various neurophysiological processes, includin...
biosignaling.biomedcentral.com
March 19, 2025 at 7:50 PM