Nascent proteins emerge from the human ribosome into a cytosol packed with hundreds of different molecular chaperones.
Which chaperones recognise specific nascent chains, and what dictates their binding preferences?
www.biorxiv.org/content/10.6...
Nascent proteins emerge from the human ribosome into a cytosol packed with hundreds of different molecular chaperones.
Which chaperones recognise specific nascent chains, and what dictates their binding preferences?
www.biorxiv.org/content/10.6...
Proteins with long IDRs are prone to misfolding during protein synthesis.
This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones.
www.cell.com/cell/fulltex...
Proteins with long IDRs are prone to misfolding during protein synthesis.
This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones.
www.cell.com/cell/fulltex...