new paper out, led by @jobeneuro.bsky.social , exploring 5HT dynamics in cingulate and central amygdala, and how a history of alcohol consumption changes them!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption - Neuropsychopharmacology
Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption
www.nature.com
September 15, 2026 at 10:58 PM
new paper out, led by @jobeneuro.bsky.social , exploring 5HT dynamics in cingulate and central amygdala, and how a history of alcohol consumption changes them!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Happy to share the latest finding on anterior cingulate cortex (ACC) and information choices from @vgonzalez.bsky.social ! #neuroscience
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www.eneuro.org/content/earl...
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www.eneuro.org/content/earl...
A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices
Humans and non-humans alike often make choices to gain information, even when the information cannot be used to change the outcome. Prior research has shown the anterior cingulate cortex (ACC) is impo...
www.eneuro.org
February 13, 2025 at 10:29 PM
Happy to share the latest finding on anterior cingulate cortex (ACC) and information choices from @vgonzalez.bsky.social ! #neuroscience
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www.eneuro.org/content/earl...
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www.eneuro.org/content/earl...
New study finds that pain and itch are processed by specific neurons in the cingulate cortex. I wonder what that means for theories that say that anything in these areas should be considered interoception? 🤔 www.nature.com/articles/s41...
Processing of pain and itch information by modality-specific neurons within the anterior cingulate cortex in mice - Nature Communications
How itch and pain, which are similar but distinct, are processed in the brain remains unclear. Here, the authors show modality-specific neural circuits between the anterior cingulate cortex (ACC) and ...
www.nature.com
March 6, 2025 at 2:27 PM
New study finds that pain and itch are processed by specific neurons in the cingulate cortex. I wonder what that means for theories that say that anything in these areas should be considered interoception? 🤔 www.nature.com/articles/s41...
I'm so impressed with all that's going on at @sinaibrain.bsky.social. Here are 5 highlights.
1. @bshev.bsky.social ++ are measuring dopamine and serotonin *in living human brains* and using them to predict treatment outcomes. Wow.
www.biorxiv.org/content/10.6...
1. @bshev.bsky.social ++ are measuring dopamine and serotonin *in living human brains* and using them to predict treatment outcomes. Wow.
www.biorxiv.org/content/10.6...
September 26, 2026 at 11:25 AM
I'm so impressed with all that's going on at @sinaibrain.bsky.social. Here are 5 highlights.
1. @bshev.bsky.social ++ are measuring dopamine and serotonin *in living human brains* and using them to predict treatment outcomes. Wow.
www.biorxiv.org/content/10.6...
1. @bshev.bsky.social ++ are measuring dopamine and serotonin *in living human brains* and using them to predict treatment outcomes. Wow.
www.biorxiv.org/content/10.6...
insula and cingulate once again at the top of the list for a brain marker of depression
Researchers used scans from more than 5,000 individuals to map how brain structure varies across many different cases of depression. www.nature.com/articles/s41...
July 1, 2026 at 10:04 AM
insula and cingulate once again at the top of the list for a brain marker of depression
🥳 Super excited to share our lab's first preprint, led by @hungyun.bsky.social
"Distinct tasks engage shared neural subspaces in human hippocampus and anterior cingulate cortex"
www.biorxiv.org/content/10.6...
🧵(1/9)
"Distinct tasks engage shared neural subspaces in human hippocampus and anterior cingulate cortex"
www.biorxiv.org/content/10.6...
🧵(1/9)
www.biorxiv.org
May 5, 2026 at 6:51 PM
🥳 Super excited to share our lab's first preprint, led by @hungyun.bsky.social
"Distinct tasks engage shared neural subspaces in human hippocampus and anterior cingulate cortex"
www.biorxiv.org/content/10.6...
🧵(1/9)
"Distinct tasks engage shared neural subspaces in human hippocampus and anterior cingulate cortex"
www.biorxiv.org/content/10.6...
🧵(1/9)
New lab paper led by @justfineneuro.bsky.social
"Complementary roles for hippocampus and anterior cingulate in composing continuous choice”, now on bioRxiv!
www.biorxiv.org/content/10.1...
"Complementary roles for hippocampus and anterior cingulate in composing continuous choice”, now on bioRxiv!
www.biorxiv.org/content/10.1...
Complementary roles for hippocampus and anterior cingulate in composing continuous choice
Naturalistic, goal directed behavior often requires continuous actions directed at dynamically changing goals. In this context, the closest analogue to choice is a strategic reweighting of multiple go...
www.biorxiv.org
March 25, 2025 at 7:42 PM
New lab paper led by @justfineneuro.bsky.social
"Complementary roles for hippocampus and anterior cingulate in composing continuous choice”, now on bioRxiv!
www.biorxiv.org/content/10.1...
"Complementary roles for hippocampus and anterior cingulate in composing continuous choice”, now on bioRxiv!
www.biorxiv.org/content/10.1...
Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex
Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex
How the cortex maintains stable memories despite highly volatile individual cell activity remains a fundamental puzzle. Using long-term imaging in mice, Descamps et al. reveal that the anterior cingulate cortex overcomes single-cell instability through collective network-level organization, creating stable and efficient population codes for spatial objects.
dlvr.it
September 23, 2026 at 11:23 PM
Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex
#TWiNPP
Ritchie et al. examine how binge alcohol drinking alters serotonin dynamics in the anterior cingulate cortex and central amygdala. Results highlight circuit-specific roles for serotonin in alcohol-related behaviors
www.nature.com/articles/s41...
Ritchie et al. examine how binge alcohol drinking alters serotonin dynamics in the anterior cingulate cortex and central amygdala. Results highlight circuit-specific roles for serotonin in alcohol-related behaviors
www.nature.com/articles/s41...
Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption - Neuropsychopharmacology
Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption
www.nature.com
September 22, 2026 at 5:58 PM
#TWiNPP
Ritchie et al. examine how binge alcohol drinking alters serotonin dynamics in the anterior cingulate cortex and central amygdala. Results highlight circuit-specific roles for serotonin in alcohol-related behaviors
www.nature.com/articles/s41...
Ritchie et al. examine how binge alcohol drinking alters serotonin dynamics in the anterior cingulate cortex and central amygdala. Results highlight circuit-specific roles for serotonin in alcohol-related behaviors
www.nature.com/articles/s41...
Some #FluorescenceFriday content for you - check out these anterior cingulate cortex neurons that project to the superior colliculus. Image by @izzabellagreen.bsky.social 🧠
December 12, 2025 at 5:20 PM
Some #FluorescenceFriday content for you - check out these anterior cingulate cortex neurons that project to the superior colliculus. Image by @izzabellagreen.bsky.social 🧠
Nature research paper: Evidence accumulation from experience and observation in the cingulate cortex
go.nature.com/4qE2Uu0
go.nature.com/4qE2Uu0
Evidence accumulation from experience and observation in the cingulate cortex - Nature
Humans and monkeys integrated experiential and observational evidence during a two-player task, and the anterior cingulate cortex combined the information sources into a unified neural belief representation that explains behavioural asymmetries.
go.nature.com
January 11, 2026 at 7:38 PM
Nature research paper: Evidence accumulation from experience and observation in the cingulate cortex
go.nature.com/4qE2Uu0
go.nature.com/4qE2Uu0
As we near the end of Insula week, I want to introduce you to Insula's bestie, Anterior Cingulate Cortex (ACC).
Left: ACC (yellow)
Right: "Insula" (Anterior Insular Cortex, AIC; green).
Left: ACC (yellow)
Right: "Insula" (Anterior Insular Cortex, AIC; green).
November 15, 2024 at 9:11 PM
As we near the end of Insula week, I want to introduce you to Insula's bestie, Anterior Cingulate Cortex (ACC).
Left: ACC (yellow)
Right: "Insula" (Anterior Insular Cortex, AIC; green).
Left: ACC (yellow)
Right: "Insula" (Anterior Insular Cortex, AIC; green).
Been awhile, but re-appearing with some #FluorescenceFriday
Neurons in the cingulate cortex projecting to locus coeruleus 🔴 or the ventral tegmental area 🟢 in the mouse brain
Neurons in the cingulate cortex projecting to locus coeruleus 🔴 or the ventral tegmental area 🟢 in the mouse brain
November 8, 2024 at 1:38 PM
Been awhile, but re-appearing with some #FluorescenceFriday
Neurons in the cingulate cortex projecting to locus coeruleus 🔴 or the ventral tegmental area 🟢 in the mouse brain
Neurons in the cingulate cortex projecting to locus coeruleus 🔴 or the ventral tegmental area 🟢 in the mouse brain
Incredibly excited to share the latest published work from the lab: www.science.org/doi/10.1126/.... Using a range of techniques, including closed-loop optogenetics, we show that the ACC modulates pupil linked arousal in real time. Great summary of our findings here: scienceblog.com/your-brain-h...
The anterior cingulate cortex modulates pupil-linked arousal
The anterior cingulate cortex modulates pupil-linked arousal in real time.
www.science.org
May 12, 2026 at 2:21 PM
Incredibly excited to share the latest published work from the lab: www.science.org/doi/10.1126/.... Using a range of techniques, including closed-loop optogenetics, we show that the ACC modulates pupil linked arousal in real time. Great summary of our findings here: scienceblog.com/your-brain-h...
Excited to share my latest work just out in @pnas.org! This NIH MOSAIC K99-funded project identifies a top-down cortical circuit—from cingulate to auditory cortex—that supports auditory perceptual performance in challenging listening conditions: www.pnas.org/doi/10.1073/...
The cingulate cortex facilitates auditory perception under challenging listening conditions | PNAS
We often exert greater cognitive resources (i.e., listening effort) to understand
speech under challenging acoustic conditions. This mechanism can ...
www.pnas.org
April 4, 2025 at 7:00 PM
Excited to share my latest work just out in @pnas.org! This NIH MOSAIC K99-funded project identifies a top-down cortical circuit—from cingulate to auditory cortex—that supports auditory perceptual performance in challenging listening conditions: www.pnas.org/doi/10.1073/...
"..rostral Anterior Cingulate Cortex develops a highly structured yet compact, scalable representation anchored in states at the start and end of self-organized sequences."
Cognitive Graphs of Latent Structure in Rostral Anterior Cingulate Cortex
www.biorxiv.org/content/10.1...
Cognitive Graphs of Latent Structure in Rostral Anterior Cingulate Cortex
www.biorxiv.org/content/10.1...
Cognitive Graphs of Latent Structure in Rostral Anterior Cingulate Cortex
Mental maps of environmental structure enable the flexibility that defines intelligent behavior. We describe a striking internal representation in rat prefrontal cortex that exhibits hallmarks of a wo...
www.biorxiv.org
May 8, 2025 at 10:26 AM
"..rostral Anterior Cingulate Cortex develops a highly structured yet compact, scalable representation anchored in states at the start and end of self-organized sequences."
Cognitive Graphs of Latent Structure in Rostral Anterior Cingulate Cortex
www.biorxiv.org/content/10.1...
Cognitive Graphs of Latent Structure in Rostral Anterior Cingulate Cortex
www.biorxiv.org/content/10.1...
When you experience a burn, your anterior cingulate cortex and anterior insula light up. These regions of the brain tell you it hurts. “I am wounded,” they say. “Please help.”
MRI scans of brains experiencing rejection or social loss have the same activity. “I am wounded,” they say. “Please help.”
MRI scans of brains experiencing rejection or social loss have the same activity. “I am wounded,” they say. “Please help.”
March 17, 2026 at 1:50 AM
When you experience a burn, your anterior cingulate cortex and anterior insula light up. These regions of the brain tell you it hurts. “I am wounded,” they say. “Please help.”
MRI scans of brains experiencing rejection or social loss have the same activity. “I am wounded,” they say. “Please help.”
MRI scans of brains experiencing rejection or social loss have the same activity. “I am wounded,” they say. “Please help.”
Exciting new results from the lab -- *visual* receptive fields in motor and cingulate cortex! Great work from Tony Lien 🧠🧪
Highly selective visual receptive fields in mouse frontal cortex https://www.biorxiv.org/content/10.1101/2025.03.25.645272v1
March 27, 2025 at 5:45 PM
Exciting new results from the lab -- *visual* receptive fields in motor and cingulate cortex! Great work from Tony Lien 🧠🧪
Remember, kids, we meditate to decouple the connection between the Anterior Cingulate Cortex and the Amygdala.
Less stress is the goal.
Less stress is the goal.
February 19, 2025 at 4:36 AM
Remember, kids, we meditate to decouple the connection between the Anterior Cingulate Cortex and the Amygdala.
Less stress is the goal.
Less stress is the goal.
@rudebecklab.bsky.social shows myelination changes in NHP model of subcallosal cingulate DBS, nicely convergent with themes from Michelle Monje Plenary. Increased myelination in cingulate bundle specifically in middle cingulate area via EM. #ACNP2024
December 9, 2024 at 11:19 PM
@rudebecklab.bsky.social shows myelination changes in NHP model of subcallosal cingulate DBS, nicely convergent with themes from Michelle Monje Plenary. Increased myelination in cingulate bundle specifically in middle cingulate area via EM. #ACNP2024
Brain area 46 is at the center of a network for emotion regulation in marmosets, a new Science study finds. The results relate directly to motivation and responsiveness to threat, which play important roles in depression and anxiety.
Learn more in a new #SciencePerspective: https://scim.ag/4fTlB8M
Learn more in a new #SciencePerspective: https://scim.ag/4fTlB8M
August 28, 2025 at 7:53 PM
Brain area 46 is at the center of a network for emotion regulation in marmosets, a new Science study finds. The results relate directly to motivation and responsiveness to threat, which play important roles in depression and anxiety.
Learn more in a new #SciencePerspective: https://scim.ag/4fTlB8M
Learn more in a new #SciencePerspective: https://scim.ag/4fTlB8M
Honored to have made the frontal cortex (cingulate?) of @npp-journal.bsky.social reviewers this year!
January 16, 2026 at 9:26 PM
Honored to have made the frontal cortex (cingulate?) of @npp-journal.bsky.social reviewers this year!
New results!
Anterior cingulate neurons display subregion-specific interaction with frontal eye fields as revealed by combined antidromic stimulation and resting state imaging
www.biorxiv.org/content/10.1...
#neuroscience
Anterior cingulate neurons display subregion-specific interaction with frontal eye fields as revealed by combined antidromic stimulation and resting state imaging
www.biorxiv.org/content/10.1...
#neuroscience
Anterior cingulate neurons display subregion-specific interaction with frontal eye fields as revealed by combined antidromic stimulation and resting state imaging
The anterior cingulate cortex (ACC) is thought to exert cognitive control over saccade generation in the frontal eye fields (FEF), but the nature of this interaction remains unclear. Although prior im...
www.biorxiv.org
November 13, 2024 at 6:45 PM
New results!
Anterior cingulate neurons display subregion-specific interaction with frontal eye fields as revealed by combined antidromic stimulation and resting state imaging
www.biorxiv.org/content/10.1...
#neuroscience
Anterior cingulate neurons display subregion-specific interaction with frontal eye fields as revealed by combined antidromic stimulation and resting state imaging
www.biorxiv.org/content/10.1...
#neuroscience
El miedo es clave. www.sciencedirect.com/science/arti...
January 31, 2026 at 11:39 AM
El miedo es clave. www.sciencedirect.com/science/arti...