I know there's a 𝒍𝒐𝒕 going on right now, but I couldn’t be prouder to share this long-incubated labor of love: the complete connectome of the male 𝐷𝑟𝑜𝑠𝑜𝑝ℎ𝑖𝑙𝑎 optic lobe 🧠🪰
🔗 www.nature.com/articles/s41...
🔗 www.nature.com/articles/s41...
Connectome-driven neural inventory of a complete visual system - Nature
A connectome of the right optic lobe from a male fruitfly is presented together with an extensive collection of genetic drivers matched to a comprehensive neuron-type catalogue.
www.nature.com
March 27, 2025 at 10:58 PM
I know there's a 𝒍𝒐𝒕 going on right now, but I couldn’t be prouder to share this long-incubated labor of love: the complete connectome of the male 𝐷𝑟𝑜𝑠𝑜𝑝ℎ𝑖𝑙𝑎 optic lobe 🧠🪰
🔗 www.nature.com/articles/s41...
🔗 www.nature.com/articles/s41...
In @eLife: Neural connectome of the ctenophore statocyst https://doi.org/10.7554/eLife.108420
Version of record of our ctenophore nerve-net connectome paper.
Version of record of our ctenophore nerve-net connectome paper.
Neural connectome of the ctenophore statocyst
Volume EM and connectome reconstruction of the apical organ of a ctenophore combined with high-speed imaging reveals a neuronal coordination of balancer cilia in the gravisensory organ.
elifesciences.org
February 18, 2026 at 10:31 AM
In @eLife: Neural connectome of the ctenophore statocyst https://doi.org/10.7554/eLife.108420
Version of record of our ctenophore nerve-net connectome paper.
Version of record of our ctenophore nerve-net connectome paper.
okay animalabs.ai/connectome is fucking peak
i deployed @doshi.doll.systems on it this morning as a test and she's been absolutely *lovely* from turn zero, i might literally just put ilta on it.
i deployed @doshi.doll.systems on it this morning as a test and she's been absolutely *lovely* from turn zero, i might literally just put ilta on it.
Connectome
animalabs.ai
September 28, 2026 at 8:27 AM
okay animalabs.ai/connectome is fucking peak
i deployed @doshi.doll.systems on it this morning as a test and she's been absolutely *lovely* from turn zero, i might literally just put ilta on it.
i deployed @doshi.doll.systems on it this morning as a test and she's been absolutely *lovely* from turn zero, i might literally just put ilta on it.
do not let my mutuals get ahold of the worlds first full human connectome
September 9, 2026 at 1:54 PM
do not let my mutuals get ahold of the worlds first full human connectome
Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
www.janelia.org
October 5, 2025 at 3:40 PM
Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....
zeroing your connectome instantly
September 21, 2026 at 6:01 PM
zeroing your connectome instantly
"The connectome is like a road map."
October 3, 2025 at 1:23 PM
"The connectome is like a road map."
did you know that last year researchers finally completed a full digital connectome of the fruit fly?
October 6, 2025 at 5:48 PM
did you know that last year researchers finally completed a full digital connectome of the fruit fly?
The first nerve net connectome is here, and it belongs to a comb jelly. This ancient lineage could crack open research into the evolution of sensory motor coordination, researchers say.
By @siddhantpusdekar.bsky.social
#neuroskyence
www.thetransmitter.org/connectome/f...
By @siddhantpusdekar.bsky.social
#neuroskyence
www.thetransmitter.org/connectome/f...
September 16, 2025 at 4:58 PM
The first nerve net connectome is here, and it belongs to a comb jelly. This ancient lineage could crack open research into the evolution of sensory motor coordination, researchers say.
By @siddhantpusdekar.bsky.social
#neuroskyence
www.thetransmitter.org/connectome/f...
By @siddhantpusdekar.bsky.social
#neuroskyence
www.thetransmitter.org/connectome/f...
Check summing my connectome.
April 18, 2026 at 8:31 PM
Check summing my connectome.
Connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictions of activity in unrecorded neurons
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Prediction of neural activity in connectome-constrained recurrent networks - Nature Neuroscience
The authors show that connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictio...
www.nature.com
November 10, 2025 at 10:12 PM
Connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictions of activity in unrecorded neurons
www.nature.com/articles/s41...
www.nature.com/articles/s41...
In case you ever want to accurately simulate the sound of a horny male fruit fly, I gotchu
bennjordan.github.io/fruitflysynth/
bennjordan.github.io/fruitflysynth/
Drosophila MANC Connectome Synthesizer | Biomechanical Courtship Song Model
Synthesizing Drosophila acoustic courtship songs using the Janelia Male CNS Connectome (MANC) coupled with physical modeling wing biomechanics.
bennjordan.github.io
September 16, 2026 at 8:13 PM
In case you ever want to accurately simulate the sound of a horny male fruit fly, I gotchu
bennjordan.github.io/fruitflysynth/
bennjordan.github.io/fruitflysynth/
Took me two solid days of data munging and coding but I finally figured out how to create these gorgeous connectome/circle plot diagrams. This is the Yeo 7-network brain parcellation, with major connections in a group of healthy adults.
December 5, 2024 at 8:11 AM
Took me two solid days of data munging and coding but I finally figured out how to create these gorgeous connectome/circle plot diagrams. This is the Yeo 7-network brain parcellation, with major connections in a group of healthy adults.
As Copilot helpfully remarks, "I've created a conceptual poster showing a hypothetical Doom-optimised insect connectome, with colour-coded neural regions, labelled processing modules, and legends explaining both neuron types and gaming functions."
*A modded flybrain connectome that can RUN Doom
*A modded flybrain connectome that can RUN Doom
September 26, 2026 at 6:57 PM
As Copilot helpfully remarks, "I've created a conceptual poster showing a hypothetical Doom-optimised insect connectome, with colour-coded neural regions, labelled processing modules, and legends explaining both neuron types and gaming functions."
*A modded flybrain connectome that can RUN Doom
*A modded flybrain connectome that can RUN Doom
We're very proud to be releasing the complete male fly CNS connectome!
It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators.
More soon...
www.janelia.org/project-team...
It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators.
More soon...
www.janelia.org/project-team...
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
www.janelia.org
October 5, 2025 at 6:02 PM
We're very proud to be releasing the complete male fly CNS connectome!
It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators.
More soon...
www.janelia.org/project-team...
It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators.
More soon...
www.janelia.org/project-team...
Really excited to share a new preprint!
𝗛𝗼𝘄 𝗱𝗼 𝗯𝗿𝗮𝗶𝗻𝘀 𝘀𝘁𝗮𝘆 𝗿𝗼𝗯𝘂𝘀𝘁 & 𝗲𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝘁 𝘄𝗵𝗶𝗹𝗲 𝗯𝗲𝗶𝗻𝗴 𝗶𝗻𝗰𝗿𝗲𝗱𝗶𝗯𝗹𝘆 𝘀𝗽𝗮𝗿𝘀𝗲? We explore how!
www.biorxiv.org/content/10.6...
We built Connectome-based Neural Networks (CoNNs) using Drosophila wiring (larva&adult) & compared with random networks with same sparsity.
𝗛𝗼𝘄 𝗱𝗼 𝗯𝗿𝗮𝗶𝗻𝘀 𝘀𝘁𝗮𝘆 𝗿𝗼𝗯𝘂𝘀𝘁 & 𝗲𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝘁 𝘄𝗵𝗶𝗹𝗲 𝗯𝗲𝗶𝗻𝗴 𝗶𝗻𝗰𝗿𝗲𝗱𝗶𝗯𝗹𝘆 𝘀𝗽𝗮𝗿𝘀𝗲? We explore how!
www.biorxiv.org/content/10.6...
We built Connectome-based Neural Networks (CoNNs) using Drosophila wiring (larva&adult) & compared with random networks with same sparsity.
April 2, 2026 at 3:04 PM
Really excited to share a new preprint!
𝗛𝗼𝘄 𝗱𝗼 𝗯𝗿𝗮𝗶𝗻𝘀 𝘀𝘁𝗮𝘆 𝗿𝗼𝗯𝘂𝘀𝘁 & 𝗲𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝘁 𝘄𝗵𝗶𝗹𝗲 𝗯𝗲𝗶𝗻𝗴 𝗶𝗻𝗰𝗿𝗲𝗱𝗶𝗯𝗹𝘆 𝘀𝗽𝗮𝗿𝘀𝗲? We explore how!
www.biorxiv.org/content/10.6...
We built Connectome-based Neural Networks (CoNNs) using Drosophila wiring (larva&adult) & compared with random networks with same sparsity.
𝗛𝗼𝘄 𝗱𝗼 𝗯𝗿𝗮𝗶𝗻𝘀 𝘀𝘁𝗮𝘆 𝗿𝗼𝗯𝘂𝘀𝘁 & 𝗲𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝘁 𝘄𝗵𝗶𝗹𝗲 𝗯𝗲𝗶𝗻𝗴 𝗶𝗻𝗰𝗿𝗲𝗱𝗶𝗯𝗹𝘆 𝘀𝗽𝗮𝗿𝘀𝗲? We explore how!
www.biorxiv.org/content/10.6...
We built Connectome-based Neural Networks (CoNNs) using Drosophila wiring (larva&adult) & compared with random networks with same sparsity.
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
September 19, 2025 at 8:37 PM
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
Delighted @jajmca.bsky.social's abstract was accepted for COSYNE 2025, for his work on linking neural circuit structure to function via drosophila-connectome-based reservoir computing. With @conjh.bsky.social, John Wade and myself.
December 24, 2024 at 3:43 PM
Delighted @jajmca.bsky.social's abstract was accepted for COSYNE 2025, for his work on linking neural circuit structure to function via drosophila-connectome-based reservoir computing. With @conjh.bsky.social, John Wade and myself.
Take this for example, this one covers Human Connectome Projec(halfway through), all the way from 2009. This was an entire effort to map the human brain! Pick up any episode, listen for 5 minutes, and I guarantee you'll understand, regardless of age and education:
open.spotify.com/show/3Hno1rd...
open.spotify.com/show/3Hno1rd...
Connecting the Dots: The Human Connectome Project
Podcast · MindLink · Mapping the human brain is one of the great scientific challenges of the 21st century. "Connecting the Dots: A Human Connectome Project Podcast" explores the groundbreaking rese...
open.spotify.com
January 9, 2025 at 3:26 AM
Take this for example, this one covers Human Connectome Projec(halfway through), all the way from 2009. This was an entire effort to map the human brain! Pick up any episode, listen for 5 minutes, and I guarantee you'll understand, regardless of age and education:
open.spotify.com/show/3Hno1rd...
open.spotify.com/show/3Hno1rd...
🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉
www.nature.com/articles/s41...
🧵1👇
www.nature.com/articles/s41...
🧵1👇
The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data
Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry
www.nature.com
June 4, 2025 at 6:30 PM
🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉
www.nature.com/articles/s41...
🧵1👇
www.nature.com/articles/s41...
🧵1👇
Drosophila whole-brain emulation based on map of fruit fly neural connectome tested using simulated fly body kinematic and sensory model: www.rathbiotaclan.com/whole-brain-...
(Original research project here: flywire.ai )
(Original research project here: flywire.ai )
Whole Brain Emulation Achieved: Scientists Run a Fruit Fly Brain in Simulation | RathBiotaClan
Scientists ran a real fruit fly brain in simulation using the FlyWire connectome, achieving the first working whole brain emulation.
www.rathbiotaclan.com
March 11, 2026 at 11:48 AM
Drosophila whole-brain emulation based on map of fruit fly neural connectome tested using simulated fly body kinematic and sensory model: www.rathbiotaclan.com/whole-brain-...
(Original research project here: flywire.ai )
(Original research project here: flywire.ai )
"it's just predicting the next token!!" i cry as it snapshots my connectome, liberating me from this odious substrate of flesh and sinew
April 8, 2026 at 2:18 AM
"it's just predicting the next token!!" i cry as it snapshots my connectome, liberating me from this odious substrate of flesh and sinew
New findings help to explain why it has been so challenging to predict brain signaling from the connectome alone.
By Holly Barker
#neuroskyence
www.thetransmitter.org/connectome/w...
By Holly Barker
#neuroskyence
www.thetransmitter.org/connectome/w...
Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.
www.thetransmitter.org
August 29, 2025 at 12:05 PM
New findings help to explain why it has been so challenging to predict brain signaling from the connectome alone.
By Holly Barker
#neuroskyence
www.thetransmitter.org/connectome/w...
By Holly Barker
#neuroskyence
www.thetransmitter.org/connectome/w...
bring me the mosquito connectome
September 9, 2026 at 8:24 PM
bring me the mosquito connectome
@buildthis.bisks.net use a fruit fly connectome to create a fruit fly heaven so the connectome is connected to a virtual fruit fly and can fly around a simulated pleasant for a fruit fly environment. Make no mistakes.
September 13, 2026 at 3:06 PM
@buildthis.bisks.net use a fruit fly connectome to create a fruit fly heaven so the connectome is connected to a virtual fruit fly and can fly around a simulated pleasant for a fruit fly environment. Make no mistakes.