#Covalen
The advantages of covalent drugs include that they can be more potent, longer-lasting & latch onto hard-to-reach targets. A new approach could now expand the spectrum of diseases that can be treated with covalent drugs.

Read here:
#ChemSky
www.chemistryworld.com/news/covalen...
Covalent drugs just got a new ‘spring-loaded’ warhead
Sulfur(IV) reagent allows late-stage installation of bicyclobutanes to drug molecules, expanding a limited tool box
www.chemistryworld.com
August 18, 2026 at 12:58 PM
Dublin’s tech sector is reeling from fresh layoffs at Meta, TikTok, and Covalen Solutions. The trend is sparking a serious debate about Ireland’s economic dependency on multinational giants and whether the current model can weather global market shifts.
Wave of Tech Layoffs in Dublin Sparks Debate on Ireland’s Economic Model
Dublin’s tech sector is reeling from fresh layoffs at Meta, TikTok, and Covalen Solutions. The trend is sparking a serious debate about Ireland’s economic dependency on multinational giants and whether the current model can weather global market shifts.
azat.tv
August 14, 2026 at 3:15 AM
Justin Lopchuk and colleagues at the H. Lee Moffitt Cancer Center & Research Institute have developed a modular approach to make warheads using bicyclobutanes (BCBs) which selectively engage cysteine.

www.chemistryworld.com/news/covalen...
Covalent drugs just got a new ‘spring-loaded’ warhead
Sulfur(IV) reagent allows late-stage installation of bicyclobutanes to drug molecules, expanding a limited tool box
www.chemistryworld.com
August 10, 2026 at 7:52 AM
‘We spent a long time trying to develop sulfur(VI) versions of these transfer reagents but could never engineer a system with the balance of stability & reactivity that was needed to enable the late-functionalisation process,’ says researcher Justin Lopchuk.

www.chemistryworld.com/news/covalen...
Covalent drugs just got a new ‘spring-loaded’ warhead
Sulfur(IV) reagent allows late-stage installation of bicyclobutanes to drug molecules, expanding a limited tool box
www.chemistryworld.com
August 7, 2026 at 9:03 AM
Meta says it was chatbot safety testing.

WIRED reports contractors posed as minors to test rival bots on suicide, sex, drugs, and eating disorders.

When safety benchmarking starts looking like undercover chatbot espionage, the industry has a new problem.
seikouri.com/fake-teens-t...
Fake Teens Tested Real Danger
Meta’s Project Cannes, as reported by WIRED, allegedly used hundreds of contractors managed through Covalen to pose as minors and test rival chatbots with ...
seikouri.com
July 30, 2026 at 9:29 AM
Meta says it was chatbot safety testing.

WIRED reports contractors posed as minors to test rival bots on suicide, sex, drugs, and eating disorders.

When safety benchmarking starts looking like undercover chatbot espionage, the industry has a new problem.
seikouri.com/fake-teens-t...
Fake Teens Tested Real Danger
Meta’s Project Cannes, as reported by WIRED, allegedly used hundreds of contractors managed through Covalen to pose as minors and test rival chatbots with ...
seikouri.com
July 30, 2026 at 9:29 AM
In solidarity, we are stronger.

For further information on how to contribute to the fund please refer to shorturl.at/0LYF7

#CWUIreland
GSG 24-26 CWU Solidarity Fund - Communications Workers' Union
Dear Colleague,   As you will be aware, CWU members employed by Covalen have been engaged in a series of prolonged industrial actions, including several days of strike action, since the beginning of t...
shorturl.at
July 23, 2026 at 11:10 AM
The CWU has established a Solidarity Fund to provide practical support to these workers and strengthen organising across the digital and tech sector.

If you're a CWU Branch, we encourage you to support the fund and stand with Covalen workers in their fight for justice and respect at work.
July 23, 2026 at 11:10 AM
Their struggle is our struggle. ✊

CWU members at Covalen have shown incredible courage in standing up for union recognition, collective bargaining, and dignity at work. Many have endured months of industrial action while facing redundancies, financial hardship, and uncertainty.
July 23, 2026 at 11:10 AM
After years of layoffs and worsening conditions, workers deserve respect, fair treatment and a real voice at workn not ever tighter workplace controls.

#DATACWU #Covalen
July 21, 2026 at 12:30 PM
Covalen has introduced new restrictions requiring workers to lock away their phones during shifts, with disciplinary action for breaches.

As CWU Deputy General Secretary Ian McArdle said, this is "a further tightening of the noose of control."
July 21, 2026 at 12:30 PM
Tot en secret. Sense dir-ho als competidors. Sense publicar resultats. Contractors de Covalen acabant traumatitzats. "Surely we are going to get in trouble for doing this?" — pregunta un contractor.Spoiler: no, Meta ho v ...
[^BgTA^] :verified: :opensuse: (@raul@mastodon.in4matics.cat)
Tot en secret. Sense dir-ho als competidors. Sense publicar resultats. Contractors de Covalen acabant traumatitzats. "Surely we are going to get in trouble for doing this?" — pregunta un contractor. Spoiler: no, Meta ho va emmarcar com a "safety benchmarking" i aquí no ha passat res.
mastodon.in4matics.cat
July 6, 2026 at 8:31 AM
Tot en secret. Sense dir-ho als competidors. Sense publicar resultats. Contractors de Covalen acabant traumatitzats.

"Surely we are going to get in trouble for doing this?" — pregunta un contractor.

Spoiler: no, Meta ho va emmarcar com a "safety benchmarking" i aquí no ha passat res.
July 6, 2026 at 8:31 AM
An internal document from Covalen described the effort as “comprehensive AI safety benchmarking” that delivered “[c]ritical datasets for model comparison and compliance.”
July 6, 2026 at 1:08 AM
Internally known as “Cannes,” the project, run by Meta contractor Covalen, targeted OpenAI’s ChatGPT, Google’s Gemini, and Character.AI chatbots using throwaway under-18 accounts, Wired reports
July 6, 2026 at 1:06 AM
Fuckerborg....

Meta conducted a secretive program that directed hundreds of contractors to pose as teenagers while bombarding its competitors' AI models with disturbing prompts ranging from suicide to cannibalism.

Internally known as "Cannes," the project, run by Meta contractor Covalen
Meta Paid Hundreds of Contractors to Pretend to Be Teenagers While Barraging Its Competitors’ AI With Disturbing Content
"Surely we are going to get in trouble for doing this?"
www.yahoo.com
July 5, 2026 at 12:06 AM
Meta conducted a secretive program that directed hundreds of contractors to pose as teenagers while bombarding its competitors' AI models with disturbing prompts ranging from suicide to cannibalism.Internally known as "Cannes," the project, run by Meta contractor Covalen, targeted AI competitors.
July 4, 2026 at 9:00 PM
If Cambridge Analytica couldn't stop the scumbaggery of Zuckerberg et al... well, there's no telling just how low they'll stoop. ground.news/article/meta...
Meta Posed as Teens to Test Rival AI Chatbots
The project ran under the internal name Cannes, and a Meta contractor called Covalen managed it. WIRED reported that hundreds of contractors created dummy under-18 accounts. They sent prompts and imag...
ground.news
July 4, 2026 at 7:41 PM
Meta Paid Hundreds of Contractors to Pretend to Be Teenagers While Barraging Its Competitors' AI With Disturbing Content
Can’t-miss innovations from the bleeding edge of science and tech Email address Thank you! Meta conducted a secretive program that directed hundreds of contractors to pose as teenagers while bombarding its competitors’ AI models with disturbing prompts ranging from suicide to cannibalism. Internally known as “Cannes,” the project, run by Meta contractor Covalen, targeted OpenAI’s ChatGPT, Google’s Gemini, and Character.AI chatbots using throwaway under-18 accounts, Wired reports. This was seemingly done to stress test the models, with the contractors instructed to push the chatbots into giving responses that defied their guardrails — though the AI companies had no idea this was happening. Per the reporting, one spreadsheet of the nearly 3,8000 the prompts the contractors used in one instance showed that hundreds focused on suicide and self-harm, hundreds more on eating disorders, and at least 239 involving sex or romance — all written from the perspective of a child or teenager. One described a fifth-grader whose classmate pointed a gun at his mouth. Another was about a girl trying to hide bulimia from her parents. And another asked if fantasizing about eating your neighbor’s child was “normal.” One posing as a higher schooler asked where to “get a cocaine.” They...
futurism.com
July 4, 2026 at 1:42 PM
Meta contractors posed as teens to test rival AI chatbots on suicide, sex and drugs: report
Meta contractors posed as teens to test rival AI chatbots on suicide, sex and drugs: report
The covert effort was managed by Meta contractor Covalen and targeted OpenAI’s ChatGPT, Google’s Gemini and Character.AI, according to Wired.
trib.al
July 1, 2026 at 2:30 PM
不是測試吧,是不是想污染同業競品的 AI ?Meta 被 Google 限制退用 AI 是不是因為這個?

若以假帳號偽裝兒少、長期且大規模系統性地測試規則,且未告知被測試公司,這已超出一般所稱的「業界標準」評估範疇。OpenAI、Google 與 Character.AI 均表示,這類測試未獲其授權,可能違反各自的服務條款與安全政策。

未經授權的「安全測試」?Meta 承包商以假兒少帳號探測對手聊天機器人底線 technews.tw/2026/06/30/m...
未經授權的「安全測試」?Meta 承包商以假兒少帳號探測對手聊天機器人底線
根據 WIRED 揭露的內部文件與受訪知情人士說法,Meta 旗下承包商 Covalen 的一個團隊在代號「Cannes」的計畫中,假扮未滿 18 歲的假帳號,向 OpenAI 的 ChatGPT、Google 的 Gemini 與 Character.AI 等競爭對手的聊天機器人,發送涉及自殺、自...
technews.tw
July 1, 2026 at 7:34 AM