The name is bond. Covalent bond.
Being 55% water and starting a career in streaming is like a guy named Bond being a carbon based life form
March 29, 2026 at 12:34 PM
The name is bond. Covalent bond.
Downplay a book or movie: Covalent Blonde
Downplay a book or movie: Mostly Quiet on the Western Front
Downplay a book or movie: Airplane.
August 2, 2026 at 10:59 PM
Downplay a book or movie: Covalent Blonde
"Atoms want full shell. They'll become socialist to become full shell."
My spouse, explaining covalent bonding to my 15yo.
My spouse, explaining covalent bonding to my 15yo.
October 29, 2024 at 10:24 PM
"Atoms want full shell. They'll become socialist to become full shell."
My spouse, explaining covalent bonding to my 15yo.
My spouse, explaining covalent bonding to my 15yo.
hey baby let's make some covalent bonds
November 22, 2024 at 4:02 PM
hey baby let's make some covalent bonds
Cool new chemistry for covalent ligand development targeting arginine 👏
Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Ninhydrin as a covalent warhead for chemical proteomic-enabled discovery and selective engagement of reactive arginines
Covalent molecules have emerged as next-generation therapeutics and as powerful tools for perturbing fundamental biological processes. Chemical proteomic methods to screen for reactive proteinaceous a...
www.biorxiv.org
January 6, 2026 at 5:15 PM
Cool new chemistry for covalent ligand development targeting arginine 👏
Here is a "covalent organic framework"
November 30, 2024 at 1:01 PM
Here is a "covalent organic framework"
Like . . . he *discovered the covalent bond*. What are we doing here?!
September 24, 2026 at 4:54 PM
Like . . . he *discovered the covalent bond*. What are we doing here?!
The amount of BULLSHIT that covalent bonds get up to,
August 2, 2025 at 4:09 PM
The amount of BULLSHIT that covalent bonds get up to,
my molecules and your molecules. covalent bonds baby
June 4, 2025 at 1:25 AM
my molecules and your molecules. covalent bonds baby
(suavely swirling the champagne in my glass) the name’s bond. *panicking* covalent bond
July 20, 2023 at 8:37 AM
(suavely swirling the champagne in my glass) the name’s bond. *panicking* covalent bond
Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Ninhydrin as a covalent warhead for chemical proteomic-enabled discovery and selective engagement of reactive arginines
Covalent molecules have emerged as next-generation therapeutics and as powerful tools for perturbing fundamental biological processes. Chemical proteomic methods to screen for reactive proteinaceous a...
www.biorxiv.org
January 6, 2026 at 3:40 PM
Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
A comprehensive review on covalent chemical strategies for protein self-labeling from @kjohnsson.bsky.social's lab: HaloTag, SNAP-tag et al. www.annualreviews.org/content/jour...
March 20, 2025 at 8:56 PM
A comprehensive review on covalent chemical strategies for protein self-labeling from @kjohnsson.bsky.social's lab: HaloTag, SNAP-tag et al. www.annualreviews.org/content/jour...
Covalent bond truther
February 19, 2024 at 4:44 PM
Covalent bond truther
this reminds me of Prop-8-time when a BYU professor of mine said straight marriages were like ionic bonds and gay marriages were like covalent ones and you couldn’t call them the same type of bond and I was just sitting there like, but a covalent bond is stronger?
The implication with this meme is that a polycule would be multiple umbrellas connected together at theoretically equal heights, providing more coverage. Much more efficient.
October 25, 2023 at 12:37 PM
this reminds me of Prop-8-time when a BYU professor of mine said straight marriages were like ionic bonds and gay marriages were like covalent ones and you couldn’t call them the same type of bond and I was just sitting there like, but a covalent bond is stronger?
covalent bond establishing
September 5, 2026 at 11:18 AM
covalent bond establishing
If you’re trying to find covalent drug candidates, it’s worth stopping to think about whether you’re doing it the right way:
Thinking About Covalent Drug Reactivity
www.science.org
July 8, 2025 at 6:33 PM
If you’re trying to find covalent drug candidates, it’s worth stopping to think about whether you’re doing it the right way:
hey girl do you like covalent bonds because i will absolutely get attached
November 20, 2025 at 1:51 AM
hey girl do you like covalent bonds because i will absolutely get attached
Great paper by the group of @jtbush.bsky.social with first author @harrywilders.bsky.social in @angewandtechemie.bsky.social. They established a direct-to-biology approach to quickly screen covalent protein ligands and advance the covalent hits into a non-covalent inhibitor series. #ChemSky #ChemBio
I am happy to share that our recent work has been published in Angewandte Chemie.
We demonstrate how ‘direct-to-biology’ screening can accelerate optimisation campaigns, yielding potent covalent and non-covalent inhibitors from reactive fragment hits.
onlinelibrary.wiley.com/doi/full/10....
We demonstrate how ‘direct-to-biology’ screening can accelerate optimisation campaigns, yielding potent covalent and non-covalent inhibitors from reactive fragment hits.
onlinelibrary.wiley.com/doi/full/10....
Expedited SARS‐CoV‐2 Main Protease Inhibitor Discovery through Modular ‘Direct‐to‐Biology’ Screening
Direct-to-biology workflows promise to accelerate hit optimisation for drug discovery. Here, we describe a direct-to-biology method for the efficient synthesis and screening of cysteine-reactive frag...
onlinelibrary.wiley.com
December 11, 2024 at 9:51 PM
Great paper by the group of @jtbush.bsky.social with first author @harrywilders.bsky.social in @angewandtechemie.bsky.social. They established a direct-to-biology approach to quickly screen covalent protein ligands and advance the covalent hits into a non-covalent inhibitor series. #ChemSky #ChemBio
For my first 🦋: Some pretty orbitals for a viologen radical cation dimer. Read more about this strange covalent bonding here: pubs.acs.org/doi/abs/10.1...
December 2, 2024 at 6:24 PM
For my first 🦋: Some pretty orbitals for a viologen radical cation dimer. Read more about this strange covalent bonding here: pubs.acs.org/doi/abs/10.1...
*subtweet of everyone the last week*
Consciousness is stored in the ionic bonds.
Agency is stored in the covalent bonds.
Smooth Operator is stored in the metallic bonds.
Consciousness is stored in the ionic bonds.
Agency is stored in the covalent bonds.
Smooth Operator is stored in the metallic bonds.
September 22, 2026 at 3:39 AM
*subtweet of everyone the last week*
Consciousness is stored in the ionic bonds.
Agency is stored in the covalent bonds.
Smooth Operator is stored in the metallic bonds.
Consciousness is stored in the ionic bonds.
Agency is stored in the covalent bonds.
Smooth Operator is stored in the metallic bonds.
Lewis Acid IntegratedBifunctional Covalent OrganicFramework for Photocatalytic Regioselective C3-Carbonylation of Indoles https://pubs.acs.org/jaaucr/article/doi/10.1021/jacsau.6c00941/5439212/Lewis-Acid-Integrated-Bifunctional-Covalent
September 26, 2026 at 7:33 AM
Lewis Acid IntegratedBifunctional Covalent OrganicFramework for Photocatalytic Regioselective C3-Carbonylation of Indoles https://pubs.acs.org/jaaucr/article/doi/10.1021/jacsau.6c00941/5439212/Lewis-Acid-Integrated-Bifunctional-Covalent
