#Creatinine
I am not going to memorize 30 different creatinine levels every day. There are five categories that are clinically relevant: creatinine back to baseline, creatinine better, creatinine the same, creatinine worse, creatinine so bad patient needs dialysis.
March 17, 2025 at 9:38 PM
it’s so cool that you can so completely misunderstand something and still make money off it
July 3, 2025 at 4:36 AM
also i can't wait to get the "oh my god you're kidneys are dying" panic and i'll go "no i'm 24 and i take creatine but thank you"
February 1, 2025 at 8:04 AM
they gotta stop reporting creatinine with three significant digits
April 17, 2025 at 3:57 PM
showing up at my doctor’s home late at night, banging on his door demanding to know why he didn’t say anything about my low BUN/creatinine ratio
July 7, 2025 at 7:52 PM
OMG! A nationally televised commercial for urine albumin to creatinine ratio!
November 27, 2025 at 4:37 PM
Patient with severe heart failure getting nuclear-powered diuresis when the creatinine goes down: the kidneys are perfusing better, continue diuresis

Patient with severe heart failure getting nuclear-powered diuresis when the creatinine goes up: that’s just hemoconcentration, continue diuresis
November 15, 2024 at 7:15 PM
They want full blood exam, liver function test, albumin / creatinine ratio, follicle stimulating hormone and... uh... fingerbuttstuff?
July 25, 2025 at 6:14 AM
"Cal's creatinine levels are down and his cultivation levels are improving!"
September 23, 2026 at 9:39 PM
hemoglobin down blood pressure down creatinine up how do i solve this mystery
June 21, 2025 at 5:53 PM
It is because creatinine is a functional marker and it takes a few days for the creatinine to rise after any injury.
January 31, 2025 at 3:38 PM
another day, another consult for creatinine that’s already getting better
May 7, 2025 at 4:14 PM
Sometimes, when on call, I get consults for labs signaling a lower-than-normal creatinine.... If 2 am when this happens, I tend to be dismissive

However, here is a nice overview of ⬇️ creatinine causes

#NephSky #MedSky

🔗 karger.com/bpu/article/...
November 14, 2024 at 2:00 AM
if you give a large enough bolus of fluid over a quick enough timeframe, the creatinine *will* go down
May 26, 2025 at 3:14 PM
another night, another page for “hey just wanna let you know their creatinine went from 9 to 10” in someone who is already on dialysis.
March 29, 2025 at 11:34 AM
creatinine went form 0.81 to 1.09 to 0.90 in less than 24 hours. what am i supposed to do with this
i am suspending the nocturnist's nephro consulting privileges until further notice
April 24, 2025 at 3:53 PM
For my more imperial-minded audience, a creatinine level of 400 μmol/L is equivalent to 0.000377614 lbs/gal
Diuretic threshold is tied to renal function. The higher the creatinine, the higher the dose of furosemide needed to achieve a diuretic effect.

Yes - the patient with a Cr of 400 needs MORE diuretic, not less‼️
January 18, 2025 at 4:50 AM
On 7/22/25 at 9pm EST only on Bluesky!
#NephSky #MedSky join us for a lively discussion.
We're debating eGFRdiff (the gap that is sometimes present between the eGFR of cystatin C and creatinine). What does it mean, what causes it and what you should do about it. #NephJC
www.nephjc.com/news/egfrdiff
Mind The Gap: When eGFR Creatinine and Cystatin C Disagree — NephJC
This week, we will discuss the clinical significance of eGFRdiff, the difference in eGFRcys (cystatin C) and eGFRcr (creatinine).
www.nephjc.com
July 21, 2025 at 11:31 AM
“Good news, the creatinine is down from 3 to 2.2”

Family member: “And what’s the GFR?”

❌ “We actually can’t tell what the GFR is when the patient’s not in steady state. We need the creatinine to be the same day to day to make that assessment, and even then that’s just an estimate.”

✅ “It’s 42.”
March 26, 2025 at 3:47 PM
If you are on prep & especially if you are taking creatine too, make sure your Dr is checking your creatinine levels.

I realized my last prep labs didn’t include a test for creatinine so I had my Dr add it to my current.

FYI creatinine level is an indicator of kidney health.
January 30, 2025 at 11:03 PM
Case in point, something that comes up almost every day in discussions with both patients and other physicians: inverse relationships are not, apparently, intuitive. An increase in creatinine from 1 to 2 is a much larger drop in GFR than an increase from 4 to 5.
December 30, 2024 at 4:29 PM
super important point 👇

sometimes creatinine falls due to dilution from large-volume fluid resuscitation.

if the urine output is zero then the GFR must be zero (regardless of how much the creatinine has decreased).
The serum creatinine level is a concentration, amount per volume.

If you quickly expand plasma volume by 20%, the Cr will decrease by ~20%, saying nothing of GFR.

Same goes for ALT, WBC, CRP, and other values that we trend and sometimes overinterpret small fluctuations of.
September 7, 2025 at 3:55 PM
another day, another consult for “help the creatinine went up on this healthy 25 year old who has been vomiting for the past three days, what do i DO?”
June 15, 2025 at 2:41 PM
Friday flex! I started increasing my protein intake and taking creatinine daily which is supposed to help build muscle. As much as I’d like the numbers on the scale to be smaller I’m basing my success on how I feel, how are my clothes fitting and am I ok with what I’m seeing in the mirror.
January 9, 2026 at 2:31 PM