Our story with @hobbslabutah.bsky.social discovering CBASS sensing of phage proteases out now in @science.org
New data include CBASS recognition of diverse proteases beyond T4, and verifying CD-NTase activation loop cleavage as the trigger for defense in vivo
www.science.org/doi/10.1126/...
New data include CBASS recognition of diverse proteases beyond T4, and verifying CD-NTase activation loop cleavage as the trigger for defense in vivo
www.science.org/doi/10.1126/...
October 1, 2026 at 7:07 PM
Our story with @hobbslabutah.bsky.social discovering CBASS sensing of phage proteases out now in @science.org
New data include CBASS recognition of diverse proteases beyond T4, and verifying CD-NTase activation loop cleavage as the trigger for defense in vivo
www.science.org/doi/10.1126/...
New data include CBASS recognition of diverse proteases beyond T4, and verifying CD-NTase activation loop cleavage as the trigger for defense in vivo
www.science.org/doi/10.1126/...
One of this morning's talks is @kevin-dean.bsky.social explaining how to do cyclic IF for ExM
#I2KxBINA
#I2KxBINA
September 30, 2026 at 3:11 PM
One of this morning's talks is @kevin-dean.bsky.social explaining how to do cyclic IF for ExM
#I2KxBINA
#I2KxBINA
I imlemented Matrix Groups for a Symmetry Representation. Here the cyclic C6.
October 4, 2026 at 5:12 AM
I imlemented Matrix Groups for a Symmetry Representation. Here the cyclic C6.
On the cyclic benefits of intermittent fasting and metabolic switching, this is an outstanding new perspective @naturemetabolism.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42...
March 14, 2025 at 1:56 PM
On the cyclic benefits of intermittent fasting and metabolic switching, this is an outstanding new perspective @naturemetabolism.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42...
She's home ☺️❤️ (plushie by Cyclic Redundancy)
January 8, 2026 at 10:35 AM
She's home ☺️❤️ (plushie by Cyclic Redundancy)
happy solstice to y'all following the cyclic whims of our nearest star
December 21, 2024 at 10:56 AM
happy solstice to y'all following the cyclic whims of our nearest star
This is what they mean by the cyclic themes of typemoon works
January 8, 2026 at 7:25 PM
This is what they mean by the cyclic themes of typemoon works
It wasn’t an antisemitic terror attack, it was an anti-Israel revenge killing. Violence is cyclic.
May 22, 2025 at 10:49 AM
It wasn’t an antisemitic terror attack, it was an anti-Israel revenge killing. Violence is cyclic.
Continuous directed evolution of cyclic peptides in cells to inhibit protein aggregation. From Tina Wang et al. #chembio #ChemSky www.nature.com/articles/s41...
Rapid discovery of cyclic peptide protein aggregation inhibitors by continuous selection - Nature Chemical Biology
A platform for the continuous selection of protein aggregation inhibitors from genetically encoded cyclic peptide libraries in Escherichia coli was developed. This platform was used to discover cyclic...
www.nature.com
January 14, 2025 at 12:28 AM
Continuous directed evolution of cyclic peptides in cells to inhibit protein aggregation. From Tina Wang et al. #chembio #ChemSky www.nature.com/articles/s41...
Given he only released this diagnosis to change the news cyclic, I don’t think it should be called CVI. It’s closer to Epstein bar.
July 17, 2025 at 11:04 PM
Given he only released this diagnosis to change the news cyclic, I don’t think it should be called CVI. It’s closer to Epstein bar.
Uh oh, has the “Who Is A Real New Yorker” discourse started again? (sigh) It’s cyclic, like sunspot maxima(e)… 😏
I truly don’t understand this “transplant” nonsense. The whole THING about NYC is that ppl come here from other places to mutate into New Yorkers! TO SEE IF THEY CAN BE KING OF THE HILL, TOP OF THE HEAP! Imho a rando who moved here a year ago is the MOST NY person. Welcome Ohio rando, have a bagel
September 21, 2026 at 10:10 AM
Uh oh, has the “Who Is A Real New Yorker” discourse started again? (sigh) It’s cyclic, like sunspot maxima(e)… 😏
A model of the cyclic universe suggests that dark matter could be a population of black holes predating the Big Bang. www.wired.com/story/dark-m...
Dark Matter May Be Made of Black Holes From Another Universe
A model of the cyclic universe suggests that dark matter could be a population of black holes predating the Big Bang.
www.wired.com
April 16, 2026 at 7:55 PM
A model of the cyclic universe suggests that dark matter could be a population of black holes predating the Big Bang. www.wired.com/story/dark-m...
New paper! A fun version of cyclic cosmology that is *exactly* periodic. So your life has been lived before, and will be lived again, an infinite number of times. Based directly on quantum state evolution.
New on the Archive:
Carroll, Sean M. and Diachenko, Nadiia and Dulani, Saakshi (2026) Toward a Phenomenologically Acceptable Quantum Cyclic Universe. [Preprint]
https://philsci-archive.pitt.edu/29823/
Carroll, Sean M. and Diachenko, Nadiia and Dulani, Saakshi (2026) Toward a Phenomenologically Acceptable Quantum Cyclic Universe. [Preprint]
https://philsci-archive.pitt.edu/29823/
May 31, 2026 at 3:18 PM
New paper! A fun version of cyclic cosmology that is *exactly* periodic. So your life has been lived before, and will be lived again, an infinite number of times. Based directly on quantum state evolution.
Great to have our manuscript with @sokrypton.org 's lab describing AfCyDesign finally out in @natcomms.bsky.social . Structure prediction, sequence redesign, de novo hallucination of cyclic peptides, and some binder design examples in this version.
rdcu.be/em0vA
rdcu.be/em0vA
Cyclic peptide structure prediction and design using AlphaFold2
Nature Communications - AfCycDesign: Cyclic offset to the relative positional encoding in AlphaFold2 enables accurate structure prediction, sequence redesign, and de novo hallucination of cyclic...
rdcu.be
May 23, 2025 at 7:07 PM
Great to have our manuscript with @sokrypton.org 's lab describing AfCyDesign finally out in @natcomms.bsky.social . Structure prediction, sequence redesign, de novo hallucination of cyclic peptides, and some binder design examples in this version.
rdcu.be/em0vA
rdcu.be/em0vA
"Cyclic tornadic supercell in Arnett, Oklahoma, USA 🇺🇸."
🙏🏼🌎🕊️
📷 Photo by Silver Lining©️
🙏🏼🌎🕊️
📷 Photo by Silver Lining©️
May 24, 2025 at 12:31 PM
"Cyclic tornadic supercell in Arnett, Oklahoma, USA 🇺🇸."
🙏🏼🌎🕊️
📷 Photo by Silver Lining©️
🙏🏼🌎🕊️
📷 Photo by Silver Lining©️
In a collaboration between the Patel, Aravind, and my group, we asked how far cyclic nucleotide signalling in bacterial antiviral immunity can diversify. Pycsar systems use cyclic pyrimidines. Can related systems also use cyclic purines?
August 15, 2026 at 12:05 PM
In a collaboration between the Patel, Aravind, and my group, we asked how far cyclic nucleotide signalling in bacterial antiviral immunity can diversify. Pycsar systems use cyclic pyrimidines. Can related systems also use cyclic purines?
March 1, 2025 at 4:09 AM
every cyclic discourse about trans women can be summed up as "someone forgot that basic rules for talking to strangers still apply to strangers who are trans women, and now we're mad that trans women reminded us of it"
December 1, 2024 at 11:46 PM
every cyclic discourse about trans women can be summed up as "someone forgot that basic rules for talking to strangers still apply to strangers who are trans women, and now we're mad that trans women reminded us of it"
Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...
The Panoptes system uses decoy cyclic nucleotides to defend against phage - Nature
The Panoptes antiphage system defends bacteria by detecting phage-encoded counter-defences that sequester cyclic nucleotide signals, triggering membrane disruption and highlighting a broader strategy of sensing immune evasion through second-messenger surveillance.
www.nature.com
October 1, 2025 at 4:05 PM
Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...
Nasty cyclic storm
March 15, 2025 at 2:06 AM
Nasty cyclic storm