New from our lab in @jcellsci.bsky.social: the earliest cell divisions help build the #zebrafish left-right organizer. #Cytokinetic bridges recruit actin and mark where rosettes form. Block early #divisions and the organ stays attached to the surface layer. Timing matters. doi.org/10.1242/jcs.264896
Mitotically driven cytoskeletal reorganization governs zebrafish left–right organizer detachment from enveloping layer and lumen morphogenesis
Highlighted Article: Early cytokinetic bridges in dorsal forerunner cells (DFCs) recruit actin to seed rosette centers, driving the transition from DFC–enveloping layer to DFC–DFC attachments that ena...
doi.org
October 28, 2026 at 11:24 AM
New from our lab in @jcellsci.bsky.social: the earliest cell divisions help build the #zebrafish left-right organizer. #Cytokinetic bridges recruit actin and mark where rosettes form. Block early #divisions and the organ stays attached to the surface layer. Timing matters. doi.org/10.1242/jcs.264896
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory: Cell Reports www.cell.com/cell-reports...
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
Using in vitro reconstitution assays and live-cell imaging, Adriaans et al. show how
Bud3 and Bud4 drive septin double-ring assembly at the budding yeast division site
during cytokinesis. Their findin...
www.cell.com
October 7, 2026 at 1:02 PM
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory: Cell Reports www.cell.com/cell-reports...
We’re excited to welcome Takashi Murata, joining us all the way from Japan, to tell us how microtubules mediate post-cytokinetic cell wall synthesis in Closterium #MAdLand2026 #plantsci
September 30, 2026 at 3:42 PM
We’re excited to welcome Takashi Murata, joining us all the way from Japan, to tell us how microtubules mediate post-cytokinetic cell wall synthesis in Closterium #MAdLand2026 #plantsci
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
Using in vitro reconstitution assays and live-cell imaging, Adriaans et al. show how Bud3 and Bud4 drive septin double-ring assembly at the budding yeast division site during cytokinesis. Their findings also reveal how these proteins establish a septin-dependent memory of cytokinesis, providing insight into the mechanisms underlying division-site organization and inheritance.
dlvr.it
September 26, 2026 at 2:38 PM
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
A multivalent docking platform and Rcn1-mediated inhibition control the extent of calcineurin recruitment to the cell division site for the dephosphorylation of multiple cytokinetic proteins https://www.biorxiv.org/content/10.64898/2026.09.14.751435v1
September 21, 2026 at 3:30 AM
A multivalent docking platform and Rcn1-mediated inhibition control the extent of calcineurin recruitment to the cell division site for the dephosphorylation of multiple cytokinetic proteins https://www.biorxiv.org/content/10.64898/2026.09.14.751435v1
A multivalent docking platform and Rcn1-mediated inhibition control the extent of calcineurin recruitment to the cell division site for the dephosphorylation of multiple cytokinetic proteins https://www.biorxiv.org/content/10.64898/2026.09.14.751435v1
September 21, 2026 at 3:30 AM
A multivalent docking platform and Rcn1-mediated inhibition control the extent of calcineurin recruitment to the cell division site for the dephosphorylation of multiple cytokinetic proteins https://www.biorxiv.org/content/10.64898/2026.09.14.751435v1
Developmental regulation of cytokinetic abscission in animal stem cells
#Drosophila
#Drosophila
Developmental regulation of cytokinetic abscission in animal stem cells
#Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
September 9, 2026 at 4:23 AM
Developmental regulation of cytokinetic abscission in animal stem cells
#Drosophila
#Drosophila
🧠 #Yeast cells remember where they divided. Bud neck septin double ring acts as a selective spatial memory, concentrating proteins that mark cytokinetic remnants & preserving molecular record of division to subsequent cell generations
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
August 31, 2026 at 10:24 PM
🧠 #Yeast cells remember where they divided. Bud neck septin double ring acts as a selective spatial memory, concentrating proteins that mark cytokinetic remnants & preserving molecular record of division to subsequent cell generations
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: Current Biology www.cell.com/current-biol...
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics
Dibsy et al. show that proteasomal degradation of the Aurora B kinase is required for cytokinetic abscission in human cells. Aurora B degradation reduces the phosphorylation of its substrate, CHMP4C, at the intercellular bridge, which in turn promotes the ESCRT-III polymer dynamics required for cytokinetic abscission.
www.cell.com
August 31, 2026 at 2:24 PM
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: Current Biology www.cell.com/current-biol...
RRID:AB_2532235 from @thermofishersci.bsky.social was used by authors in their Cell Reports paper. RRIDs improve reproducibility in scientific research. #STMpublishing #RRID #accelerateopenscience
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
Read the full paper: Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
doi.org
August 31, 2026 at 7:00 AM
RRID:AB_2532235 from @thermofishersci.bsky.social was used by authors in their Cell Reports paper. RRIDs improve reproducibility in scientific research. #STMpublishing #RRID #accelerateopenscience
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics
#microbiology #cellbiology #MicroSky
@currentbiology.bsky.social
www.sciencedirect.com/science/arti...
#microbiology #cellbiology #MicroSky
@currentbiology.bsky.social
www.sciencedirect.com/science/arti...
August 30, 2026 at 2:56 PM
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics
#microbiology #cellbiology #MicroSky
@currentbiology.bsky.social
www.sciencedirect.com/science/arti...
#microbiology #cellbiology #MicroSky
@currentbiology.bsky.social
www.sciencedirect.com/science/arti...
@proteintech.bsky.social's resource, RRID:AB_10603358, was just reported to be used in the paper. Thanks for making your methods matter! #STMpublishing #reproducibility #methodsmatter
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics
Read the full paper: The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics
doi.org
August 28, 2026 at 7:00 AM
@proteintech.bsky.social's resource, RRID:AB_10603358, was just reported to be used in the paper. Thanks for making your methods matter! #STMpublishing #reproducibility #methodsmatter
Check our latest story about the control of cytokinetic abscission by Aurora B degradation!
Congrats to Rayane and all coauthors!
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: Current Biology www.cell.com/current-biol...
Congrats to Rayane and all coauthors!
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: Current Biology www.cell.com/current-biol...
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics
Dibsy et al. show that proteasomal degradation of the Aurora B kinase is required
for cytokinetic abscission in human cells. Aurora B degradation reduces the phosphorylation
of its substrate, CHMP4C, ...
www.cell.com
August 25, 2026 at 2:31 PM
Check our latest story about the control of cytokinetic abscission by Aurora B degradation!
Congrats to Rayane and all coauthors!
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: Current Biology www.cell.com/current-biol...
Congrats to Rayane and all coauthors!
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: Current Biology www.cell.com/current-biol...
🎉CHECK OUT📣OUR PAPER📝
Happy😍to share with you our paper published in @currentbiology.bsky.social from @echardlab-pasteur.bsky.social @cnrs.fr
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: www.sciencedirect.com/science/arti...
Happy😍to share with you our paper published in @currentbiology.bsky.social from @echardlab-pasteur.bsky.social @cnrs.fr
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: www.sciencedirect.com/science/arti...
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics
Cytokinesis finalizes cell division by physically separating the daughter cells. After furrow ingression, the intercellular bridge (ICB) connecting th…
www.sciencedirect.com
August 24, 2026 at 5:27 PM
🎉CHECK OUT📣OUR PAPER📝
Happy😍to share with you our paper published in @currentbiology.bsky.social from @echardlab-pasteur.bsky.social @cnrs.fr
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: www.sciencedirect.com/science/arti...
Happy😍to share with you our paper published in @currentbiology.bsky.social from @echardlab-pasteur.bsky.social @cnrs.fr
The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: www.sciencedirect.com/science/arti...
Interesting paper, although if I'm going to be nit-picky--SF3B1 does not have catalytic activity (it is a RNA binding protein/protein scaffold). In addition, potential non-splicing roles for SF3B1 have been found elsewhere, e.g.,in histone pre-mRNA maturation
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
RNA splicing is required for timely completion of abscission and is modulated by the abscission checkpoint
The abscission checkpoint pauses the progression of cytokinetic abscission at the intercellular bridge when various checkpoint-sustaining errors are sensed. A unique cytoplasmic organelle, the absciss...
www.biorxiv.org
November 11, 2025 at 6:44 PM
Interesting paper, although if I'm going to be nit-picky--SF3B1 does not have catalytic activity (it is a RNA binding protein/protein scaffold). In addition, potential non-splicing roles for SF3B1 have been found elsewhere, e.g.,in histone pre-mRNA maturation
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Happy #MicroscopyMonday!
Walter Wanyoike, an undergrad in the lab, caught some really cool cytokinetic mishaps! Cytokinesis is the last step of cell division, where the daughter cells pinch apart. The 1st cell divides into 3, and the 2nd cell tries and tries but doesn't quite get there.
Walter Wanyoike, an undergrad in the lab, caught some really cool cytokinetic mishaps! Cytokinesis is the last step of cell division, where the daughter cells pinch apart. The 1st cell divides into 3, and the 2nd cell tries and tries but doesn't quite get there.
February 25, 2025 at 1:40 AM
Happy #MicroscopyMonday!
Walter Wanyoike, an undergrad in the lab, caught some really cool cytokinetic mishaps! Cytokinesis is the last step of cell division, where the daughter cells pinch apart. The 1st cell divides into 3, and the 2nd cell tries and tries but doesn't quite get there.
Walter Wanyoike, an undergrad in the lab, caught some really cool cytokinetic mishaps! Cytokinesis is the last step of cell division, where the daughter cells pinch apart. The 1st cell divides into 3, and the 2nd cell tries and tries but doesn't quite get there.
2/ Biomolecular condensates spatially organize cellular reactions in bacteria and eukaryotic cells. PomX, PomY & PomZ form precisely one MDa-sized, nonstoichiometric, nucleoid-associated co-condensate per cell that nucleates FtsZ polymerization to form the cytokinetic FtsZ-ring in Myxococcus.
January 3, 2025 at 10:32 AM
2/ Biomolecular condensates spatially organize cellular reactions in bacteria and eukaryotic cells. PomX, PomY & PomZ form precisely one MDa-sized, nonstoichiometric, nucleoid-associated co-condensate per cell that nucleates FtsZ polymerization to form the cytokinetic FtsZ-ring in Myxococcus.
From Flow to Form: Emergence of the Cytokinetic Ring via Active Cortical Dynamics
https://arxiv.org/pdf/2604.17349
Sabyasachi Mukherjee, Anirban Sain.
https://arxiv.org/pdf/2604.17349
Sabyasachi Mukherjee, Anirban Sain.
https://arxiv.org/abs/2604.17349
arXiv abstract link
arxiv.org
April 21, 2026 at 4:35 AM
From Flow to Form: Emergence of the Cytokinetic Ring via Active Cortical Dynamics
https://arxiv.org/pdf/2604.17349
Sabyasachi Mukherjee, Anirban Sain.
https://arxiv.org/pdf/2604.17349
Sabyasachi Mukherjee, Anirban Sain.
Active Extensile Hydrogels Actuated by Living Polymers of the Bacterial Cytokinetic Protein FtsZ
https://arxiv.org/pdf/2508.04431
Mikheil Kharbedia, Diego Herráez-Aguilar, Macarena Calero, Horacio López-Menéndez, Clara Luque-Rioja, Lara H. Moleiro, Cruz Santos, Pilar Lillo, Francisco Monroy.
https://arxiv.org/pdf/2508.04431
Mikheil Kharbedia, Diego Herráez-Aguilar, Macarena Calero, Horacio López-Menéndez, Clara Luque-Rioja, Lara H. Moleiro, Cruz Santos, Pilar Lillo, Francisco Monroy.
https://arxiv.org/abs/2508.04431
arXiv abstract link
arxiv.org
August 7, 2025 at 4:33 AM
Active Extensile Hydrogels Actuated by Living Polymers of the Bacterial Cytokinetic Protein FtsZ
https://arxiv.org/pdf/2508.04431
Mikheil Kharbedia, Diego Herráez-Aguilar, Macarena Calero, Horacio López-Menéndez, Clara Luque-Rioja, Lara H. Moleiro, Cruz Santos, Pilar Lillo, Francisco Monroy.
https://arxiv.org/pdf/2508.04431
Mikheil Kharbedia, Diego Herráez-Aguilar, Macarena Calero, Horacio López-Menéndez, Clara Luque-Rioja, Lara H. Moleiro, Cruz Santos, Pilar Lillo, Francisco Monroy.
That’s the cytokinetic bridge. It’s the last thing connecting two cells after division, before they split and go their own ways.
December 6, 2024 at 11:22 PM
That’s the cytokinetic bridge. It’s the last thing connecting two cells after division, before they split and go their own ways.
🍀🔬
IMK2-IMK3 module regulates biogenesis of nascent cell walls and postcytokinetic differentiation in Arabidopsis thaliana in Science Advances from Andrei Smertenko's lab.
www.science.org/doi/full/10....
Movie: Localization of IMK2-GFP in a cytokinetic BY-2 cell.
IMK2-IMK3 module regulates biogenesis of nascent cell walls and postcytokinetic differentiation in Arabidopsis thaliana in Science Advances from Andrei Smertenko's lab.
www.science.org/doi/full/10....
Movie: Localization of IMK2-GFP in a cytokinetic BY-2 cell.
May 8, 2026 at 4:05 PM
🍀🔬
IMK2-IMK3 module regulates biogenesis of nascent cell walls and postcytokinetic differentiation in Arabidopsis thaliana in Science Advances from Andrei Smertenko's lab.
www.science.org/doi/full/10....
Movie: Localization of IMK2-GFP in a cytokinetic BY-2 cell.
IMK2-IMK3 module regulates biogenesis of nascent cell walls and postcytokinetic differentiation in Arabidopsis thaliana in Science Advances from Andrei Smertenko's lab.
www.science.org/doi/full/10....
Movie: Localization of IMK2-GFP in a cytokinetic BY-2 cell.
A paper using RRID:AB_2617417 from @dshb-antibodies.bsky.social was just published in Rxiv. RRIDs improve reproducibility in scientific research. #RRID #OpenResearch #BetterScience
The cytokinetic midbody mediates asymmetric fate specification at mitotic exit during neural stem cell division
Read the full paper: The cytokinetic midbody mediates asymmetric fate specification at mitotic exit during neural stem cell division
doi.org
May 28, 2026 at 7:06 AM
A paper using RRID:AB_2617417 from @dshb-antibodies.bsky.social was just published in Rxiv. RRIDs improve reproducibility in scientific research. #RRID #OpenResearch #BetterScience
The authors included RRIDs in their paper! RRIDs improve reproducibility in scientific research. #accelerateopenscience #RRID #STMpublishing
Cell type-specific regulation by different cytokinetic pathways in the early embryo
doi.org
November 23, 2025 at 8:00 AM
The authors included RRIDs in their paper! RRIDs improve reproducibility in scientific research. #accelerateopenscience #RRID #STMpublishing
The authors included RRIDs in their paper! RRIDs improve reproducibility in scientific research. #methodsmatter #accelerateopenscience #reproducibility
A cytokinetic ring-driven cell rotation achieves Hertwig’s rule in early development
doi.org
November 20, 2025 at 8:00 AM
The authors included RRIDs in their paper! RRIDs improve reproducibility in scientific research. #methodsmatter #accelerateopenscience #reproducibility
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #reproducibility #reproducibility #accelerateopenscience
Centrosome-, mitotic spindle- and cytokinetic bridge-specific compartmentalization of AGO2 protein in human liver cells undergoing mitosis: Non-canonical, RNAi-dependent, control of local homeostasis
doi.org
August 12, 2025 at 7:02 AM
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #reproducibility #reproducibility #accelerateopenscience