In ME/CFS clinical trials, a DSMB can be a critical safeguard for participants’ wellbeing, particularly in studies that are investigating drugs that haven’t been used frequently or at all in the disease. It can also add a layer of scientific credibility to trials.
September 23, 2026 at 2:40 PM
In ME/CFS clinical trials, a DSMB can be a critical safeguard for participants’ wellbeing, particularly in studies that are investigating drugs that haven’t been used frequently or at all in the disease. It can also add a layer of scientific credibility to trials.
Another common reason for meeting futility at the DSMB is the overestimation (clinically unrealistic) of the pre-specified treatment effect.
July 16, 2025 at 3:22 PM
Another common reason for meeting futility at the DSMB is the overestimation (clinically unrealistic) of the pre-specified treatment effect.
15. Bhattacharya makes a false parallel between trials disrupted in 2025 and those stopped during COVID (stopped to protect the safety of patients) and trials stopped by a DSMB decision (again, to respect patient safety and ethics and based on a pre-planned protocol).
February 27, 2026 at 4:23 AM
15. Bhattacharya makes a false parallel between trials disrupted in 2025 and those stopped during COVID (stopped to protect the safety of patients) and trials stopped by a DSMB decision (again, to respect patient safety and ethics and based on a pre-planned protocol).
Sorry-
DSMB = data *&* safety monitoring board
DSMB = data *&* safety monitoring board
September 6, 2025 at 9:02 PM
Sorry-
DSMB = data *&* safety monitoring board
DSMB = data *&* safety monitoring board
2. For this DSMB, I am likely the first DSMB chair to be on hospice. I stopped meds 12 hours early to clear enough for this meeting. It wasn't easy, but I didn't fall asleep, vomit, or shriek with pain.
March 16, 2026 at 10:09 PM
2. For this DSMB, I am likely the first DSMB chair to be on hospice. I stopped meds 12 hours early to clear enough for this meeting. It wasn't easy, but I didn't fall asleep, vomit, or shriek with pain.
A DSMB is an independent group of medical and scientific experts who watch over a clinical trial while it's happening. They regularly review incoming data to make sure participants aren't being harmed and that the study is running fairly and ethically.
September 23, 2026 at 2:35 PM
A DSMB is an independent group of medical and scientific experts who watch over a clinical trial while it's happening. They regularly review incoming data to make sure participants aren't being harmed and that the study is running fairly and ethically.
#Live now!
Join the #GENeva Rights & Environment Talk providing a space to discuss the situation of Murujuga, a UNESCO World Heritage Site, while taking a look at how to protect the site and cultural & environmental rights.
▶️ tiny.cc/GRET26Murujuga
📺 www.youtube.com/watch?v=Dsmb...
Join the #GENeva Rights & Environment Talk providing a space to discuss the situation of Murujuga, a UNESCO World Heritage Site, while taking a look at how to protect the site and cultural & environmental rights.
▶️ tiny.cc/GRET26Murujuga
📺 www.youtube.com/watch?v=Dsmb...
September 25, 2026 at 8:08 AM
#Live now!
Join the #GENeva Rights & Environment Talk providing a space to discuss the situation of Murujuga, a UNESCO World Heritage Site, while taking a look at how to protect the site and cultural & environmental rights.
▶️ tiny.cc/GRET26Murujuga
📺 www.youtube.com/watch?v=Dsmb...
Join the #GENeva Rights & Environment Talk providing a space to discuss the situation of Murujuga, a UNESCO World Heritage Site, while taking a look at how to protect the site and cultural & environmental rights.
▶️ tiny.cc/GRET26Murujuga
📺 www.youtube.com/watch?v=Dsmb...
✨ Thank you to everyone who joined us for the DSMB Annual Meeting 2025 & Heparan Sulfate Workshop at the University of Copenhagen!
#MatrixBiology #DSMB #HeparanSulfate #ScientificCommunity
#MatrixBiology #DSMB #HeparanSulfate #ScientificCommunity
September 12, 2025 at 2:57 PM
✨ Thank you to everyone who joined us for the DSMB Annual Meeting 2025 & Heparan Sulfate Workshop at the University of Copenhagen!
#MatrixBiology #DSMB #HeparanSulfate #ScientificCommunity
#MatrixBiology #DSMB #HeparanSulfate #ScientificCommunity
Congrats to our two winners of the @dsmb-dk.bsky.social annual meeting best oral presentation prizes! Best heparan sulfate talk sponsored by Amsbio goes to Jessica Oyie Sousa Onyeisi @gotteprof.bsky.social lab&best ECM talk sponsored by Tebubio goes to Ask Møbjerg @ismcopenhagen.bsky.social
#proudPI
#proudPI
September 9, 2025 at 3:03 PM
Congrats to our two winners of the @dsmb-dk.bsky.social annual meeting best oral presentation prizes! Best heparan sulfate talk sponsored by Amsbio goes to Jessica Oyie Sousa Onyeisi @gotteprof.bsky.social lab&best ECM talk sponsored by Tebubio goes to Ask Møbjerg @ismcopenhagen.bsky.social
#proudPI
#proudPI
At the @dsmb-dk.bsky.social Annual Meeting 2025 and PhD student Ask Møbjerg is presenting our latest work on the acute effects of exercise on ECM remodelling of human muscle-tendon tissues using snRNAseq and RNAscope 🏋️♀️🔬
@ismcopenhagen.bsky.social
@ismcopenhagen.bsky.social
September 9, 2025 at 9:48 AM
At the @dsmb-dk.bsky.social Annual Meeting 2025 and PhD student Ask Møbjerg is presenting our latest work on the acute effects of exercise on ECM remodelling of human muscle-tendon tissues using snRNAseq and RNAscope 🏋️♀️🔬
@ismcopenhagen.bsky.social
@ismcopenhagen.bsky.social
BriaCell (#$BCTX): Seventh DSMB Recommendation to Continue Bria-ABC Phase 3
Free Biotech Catalyst Calendar on Merlintrader.
www.merlintrader.com/briacell-the...
Free Biotech Catalyst Calendar on Merlintrader.
www.merlintrader.com/briacell-the...
September 24, 2026 at 8:27 AM
BriaCell (#$BCTX): Seventh DSMB Recommendation to Continue Bria-ABC Phase 3
Free Biotech Catalyst Calendar on Merlintrader.
www.merlintrader.com/briacell-the...
Free Biotech Catalyst Calendar on Merlintrader.
www.merlintrader.com/briacell-the...
OMF’s lite version of a clinical trial network (CTN Lite) will incorporate a DSMB for appropriate trials that are conducted as part of the initiative.
🔗 Read more about CTN Lite on our website: www.omf.ngo/introducing-...
🔗 Read more about CTN Lite on our website: www.omf.ngo/introducing-...
A new chapter in ME/CFS treatment research begins today—and your voice is essential to making it count. - Open Medicine Foundation
Learn more about CTN Lite, a research model designed to accelerate ME/CFS treatment trials and expand access.
www.omf.ngo
September 23, 2026 at 2:40 PM
OMF’s lite version of a clinical trial network (CTN Lite) will incorporate a DSMB for appropriate trials that are conducted as part of the initiative.
🔗 Read more about CTN Lite on our website: www.omf.ngo/introducing-...
🔗 Read more about CTN Lite on our website: www.omf.ngo/introducing-...
Oh gawd, there's DSMB stopping points
January 15, 2026 at 2:11 PM
Oh gawd, there's DSMB stopping points
I’ve got to be somewhere this morning but I started with a cursory look at this study.
Usually a paper would include plain language that says something like “this study was reviewed by such and such IRB (Protocol # 12345)”, but I don’t see that here.
gh.bmj.com/content/9/2/...
Usually a paper would include plain language that says something like “this study was reviewed by such and such IRB (Protocol # 12345)”, but I don’t see that here.
gh.bmj.com/content/9/2/...
February 21, 2026 at 3:19 PM
I’ve got to be somewhere this morning but I started with a cursory look at this study.
Usually a paper would include plain language that says something like “this study was reviewed by such and such IRB (Protocol # 12345)”, but I don’t see that here.
gh.bmj.com/content/9/2/...
Usually a paper would include plain language that says something like “this study was reviewed by such and such IRB (Protocol # 12345)”, but I don’t see that here.
gh.bmj.com/content/9/2/...
“There has been a total of 9 bone fractures occurring after children were assigned to a treatment group – 5 in treatment arm and 4 in the placebo arm. ln its analysis... the DSMB did not identify any safety concerns regarding the nature or number of fractures overall or by treatment group...”
17/n
17/n
January 17, 2025 at 3:25 PM
“There has been a total of 9 bone fractures occurring after children were assigned to a treatment group – 5 in treatment arm and 4 in the placebo arm. ln its analysis... the DSMB did not identify any safety concerns regarding the nature or number of fractures overall or by treatment group...”
17/n
17/n
Can we also have the roster of members of the DSMB.
January 19, 2026 at 4:18 PM
Can we also have the roster of members of the DSMB.
According to Dr. Kiley (from Piller) “The DSMB assesses whether there is a statistically different pattern of events between the intervention and control arms of the study. Broken bones would be reportable as adverse events to these oversight bodies. No safety concerns were identified.”
26/n
26/n
January 17, 2025 at 3:33 PM
According to Dr. Kiley (from Piller) “The DSMB assesses whether there is a statistically different pattern of events between the intervention and control arms of the study. Broken bones would be reportable as adverse events to these oversight bodies. No safety concerns were identified.”
26/n
26/n
Goodbye #MatrixNexus2025! I will miss the organisation zoom meetings with the committee. A big shout out to all the excellent science from #ECRs including DSMB travel award winner Sara M. Jørgensen 💸
#ECMatrix
@matrixbiologie.bsky.social
#ECMatrix
@matrixbiologie.bsky.social
March 28, 2025 at 1:47 PM
Goodbye #MatrixNexus2025! I will miss the organisation zoom meetings with the committee. A big shout out to all the excellent science from #ECRs including DSMB travel award winner Sara M. Jørgensen 💸
#ECMatrix
@matrixbiologie.bsky.social
#ECMatrix
@matrixbiologie.bsky.social
That’s a wrap for @dsmb-dk.bsky.social HS Workshop and Annual Meeting 2025! Thank you to all our speakers, abstract presenters & our generous sponsors ThermoFisher, Tebubio, Amsbio and Horizon 2020 🙏 Special thanks go to our outgoing chairwoman Christine Chuang and team #ECMatrix
September 9, 2025 at 1:20 PM
That’s a wrap for @dsmb-dk.bsky.social HS Workshop and Annual Meeting 2025! Thank you to all our speakers, abstract presenters & our generous sponsors ThermoFisher, Tebubio, Amsbio and Horizon 2020 🙏 Special thanks go to our outgoing chairwoman Christine Chuang and team #ECMatrix
No matter what the TV says, supplies will run short.
Fuel will be rationed, which will ration everything.
Get some cash out. Get some food in.
www.youtube.com/watch?v=DSMb...
Fuel will be rationed, which will ration everything.
Get some cash out. Get some food in.
www.youtube.com/watch?v=DSMb...
Markets Flash Back to the Past || Peter Zeihan
YouTube video by Zeihan on Geopolitics
www.youtube.com
May 9, 2026 at 8:40 AM
No matter what the TV says, supplies will run short.
Fuel will be rationed, which will ration everything.
Get some cash out. Get some food in.
www.youtube.com/watch?v=DSMb...
Fuel will be rationed, which will ration everything.
Get some cash out. Get some food in.
www.youtube.com/watch?v=DSMb...
Also
-CRO = contract research organization
-DSMB = data safety & monitoring board (aka data monitoring committee, DMC)
-CRO = contract research organization
-DSMB = data safety & monitoring board (aka data monitoring committee, DMC)
September 6, 2025 at 9:01 PM
Also
-CRO = contract research organization
-DSMB = data safety & monitoring board (aka data monitoring committee, DMC)
-CRO = contract research organization
-DSMB = data safety & monitoring board (aka data monitoring committee, DMC)
wake up babe it's time to log onto my cookie run kingdom account
youtube - www.youtube.com/watch?v=dsMb...
twitch - twitch.tv/punkbrocker
#eldenwood #vtuber #vtlive
youtube - www.youtube.com/watch?v=dsMb...
twitch - twitch.tv/punkbrocker
#eldenwood #vtuber #vtlive
January 27, 2025 at 7:09 PM
wake up babe it's time to log onto my cookie run kingdom account
youtube - www.youtube.com/watch?v=dsMb...
twitch - twitch.tv/punkbrocker
#eldenwood #vtuber #vtlive
youtube - www.youtube.com/watch?v=dsMb...
twitch - twitch.tv/punkbrocker
#eldenwood #vtuber #vtlive
If DOGE tells me what I may or may not post in FOAM, then I insist they take care of all my DSMB correspondences, my Type 5s, and my data user agreements. I'm 100% certain Big Balls does not have CITI and No FEAR training. Make them take those, too.
April 13, 2025 at 1:22 AM
If DOGE tells me what I may or may not post in FOAM, then I insist they take care of all my DSMB correspondences, my Type 5s, and my data user agreements. I'm 100% certain Big Balls does not have CITI and No FEAR training. Make them take those, too.