Lactate dehydrogenase A (#LDHA)-driven metabolic and epigenetic reprogramming in beta cell dedifferentiation during diabetes development, identifying LDHA inhibition as a promising therapeutic target. #DiabetesResearch #Pancreatic-β-cell #Dedifferentiaton link.springer.com/article/10.1...
LDHA induces beta cell dedifferentiation in diabetes through metabolic and epigenetic reprogramming - Diabetologia
Aims/hypothesis Pancreatic beta cell dedifferentiation underlies the reversible reduction in beta cell mass and function in diabetes. Exploratory research into interventional targets and adjuvant ther...
link.springer.com
December 22, 2025 at 10:58 AM
Lactate dehydrogenase A (#LDHA)-driven metabolic and epigenetic reprogramming in beta cell dedifferentiation during diabetes development, identifying LDHA inhibition as a promising therapeutic target. #DiabetesResearch #Pancreatic-β-cell #Dedifferentiaton link.springer.com/article/10.1...