Character Sheet commission for Digoxin 🤍
May 9, 2025 at 11:55 AM
Character Sheet commission for Digoxin 🤍
How a heart medication—digoxin—might help prevent cancer spread by dissolving clusters of circulating tumor cells
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 24, 2025 at 2:50 PM
How a heart medication—digoxin—might help prevent cancer spread by dissolving clusters of circulating tumor cells
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Diagnosis is usually based on clinical history.🕵️(e.g., “My son drank my leftover smoothie with pong pong kernel chunks in it”)
🧪A digoxin level may sometimes be falsely positive because cerberin can cross-react with digoxin assays (Fun fact: digoxin is cardiac glycoside medication used clinically!)
🧪A digoxin level may sometimes be falsely positive because cerberin can cross-react with digoxin assays (Fun fact: digoxin is cardiac glycoside medication used clinically!)
April 7, 2025 at 7:39 PM
Diagnosis is usually based on clinical history.🕵️(e.g., “My son drank my leftover smoothie with pong pong kernel chunks in it”)
🧪A digoxin level may sometimes be falsely positive because cerberin can cross-react with digoxin assays (Fun fact: digoxin is cardiac glycoside medication used clinically!)
🧪A digoxin level may sometimes be falsely positive because cerberin can cross-react with digoxin assays (Fun fact: digoxin is cardiac glycoside medication used clinically!)
#plants #history #botany
Digitalis purpurea - Common Foxglove
All parts are Poisonous but are the source of the cardiac medication Digoxin. Good work by Withering in 1785 who used it to treat Dropsy.
Breakthrough - 1930 by Dr. Sydney Smith who isolated Digoxin.
en.wikipedia.org/wiki/Digoxin
Digitalis purpurea - Common Foxglove
All parts are Poisonous but are the source of the cardiac medication Digoxin. Good work by Withering in 1785 who used it to treat Dropsy.
Breakthrough - 1930 by Dr. Sydney Smith who isolated Digoxin.
en.wikipedia.org/wiki/Digoxin
December 8, 2024 at 12:36 PM
#plants #history #botany
Digitalis purpurea - Common Foxglove
All parts are Poisonous but are the source of the cardiac medication Digoxin. Good work by Withering in 1785 who used it to treat Dropsy.
Breakthrough - 1930 by Dr. Sydney Smith who isolated Digoxin.
en.wikipedia.org/wiki/Digoxin
Digitalis purpurea - Common Foxglove
All parts are Poisonous but are the source of the cardiac medication Digoxin. Good work by Withering in 1785 who used it to treat Dropsy.
Breakthrough - 1930 by Dr. Sydney Smith who isolated Digoxin.
en.wikipedia.org/wiki/Digoxin
“Suicide tree,” Cerbera odollam, which is native to India/SE Asia & related to the oleander family, contains cardiogenic steroids (cardiac glycosides).
Toxicity presents similar to digoxin poisoning, with cardiac dysrhythmias, bradycardia, and hyperkalemia. Digoxin immune fab can treat its effects.
Toxicity presents similar to digoxin poisoning, with cardiac dysrhythmias, bradycardia, and hyperkalemia. Digoxin immune fab can treat its effects.
April 7, 2025 at 1:45 AM
“Suicide tree,” Cerbera odollam, which is native to India/SE Asia & related to the oleander family, contains cardiogenic steroids (cardiac glycosides).
Toxicity presents similar to digoxin poisoning, with cardiac dysrhythmias, bradycardia, and hyperkalemia. Digoxin immune fab can treat its effects.
Toxicity presents similar to digoxin poisoning, with cardiac dysrhythmias, bradycardia, and hyperkalemia. Digoxin immune fab can treat its effects.
Good explainer for the unanticipated effect of digoxin for breaking up clusters of circulating tumor cells (not yet assessed in people) www.nature.com/articles/d41...
Breaking up clusters of circulating tumour cells to halt cancer spread
The drug digoxin reduces the clustering of tumour cells.
www.nature.com
January 28, 2025 at 7:54 PM
Good explainer for the unanticipated effect of digoxin for breaking up clusters of circulating tumor cells (not yet assessed in people) www.nature.com/articles/d41...
New #cancer study showing that tumor cell #clusters in the blood (which are more #metastatic) can be disrupted by the drug digoxin - in an exciting proof of concept trial 🧪
Kurzeder, Aceto et al, ETH Zurich
Commentary by Smit & Pantel
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Kurzeder, Aceto et al, ETH Zurich
Commentary by Smit & Pantel
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Breaking up clusters of circulating tumour cells to halt cancer spread
The drug digoxin reduces the clustering of tumour cells.
www.nature.com
January 28, 2025 at 3:39 PM
New #cancer study showing that tumor cell #clusters in the blood (which are more #metastatic) can be disrupted by the drug digoxin - in an exciting proof of concept trial 🧪
Kurzeder, Aceto et al, ETH Zurich
Commentary by Smit & Pantel
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Kurzeder, Aceto et al, ETH Zurich
Commentary by Smit & Pantel
www.nature.com/articles/s41...
www.nature.com/articles/d41...
🛡️Treatment for severe cerberin toxicity involves giving digoxin antibody fragments to try and bind up and neutralize the cerberin.
Otherwise...management is supportive (treat arrhythmias, manage electrolytes, and close monitoring, etc).
Otherwise...management is supportive (treat arrhythmias, manage electrolytes, and close monitoring, etc).
April 7, 2025 at 7:39 PM
🛡️Treatment for severe cerberin toxicity involves giving digoxin antibody fragments to try and bind up and neutralize the cerberin.
Otherwise...management is supportive (treat arrhythmias, manage electrolytes, and close monitoring, etc).
Otherwise...management is supportive (treat arrhythmias, manage electrolytes, and close monitoring, etc).
In my opinion, Lochlan probably would have died. ☠️
Just one kernel is enough to be deadly, and there seemed to be ample leftovers in that nasty blender before he made his smoothie. Lochy also didn’t get any medical care or digoxin antibody fragments.
Just one kernel is enough to be deadly, and there seemed to be ample leftovers in that nasty blender before he made his smoothie. Lochy also didn’t get any medical care or digoxin antibody fragments.
April 7, 2025 at 7:39 PM
In my opinion, Lochlan probably would have died. ☠️
Just one kernel is enough to be deadly, and there seemed to be ample leftovers in that nasty blender before he made his smoothie. Lochy also didn’t get any medical care or digoxin antibody fragments.
Just one kernel is enough to be deadly, and there seemed to be ample leftovers in that nasty blender before he made his smoothie. Lochy also didn’t get any medical care or digoxin antibody fragments.
A proof-of-concept trial reported in Nature Medicine shows that the size of circulating tumor cell clusters (which can promote metastatic spread) can be reduced by treatment with the Na+/K+ ATPase inhibitor digoxin in patients with metastatic breast cancer. https://go.nature.com/40sBw6Q #Medsky 🧪
January 29, 2025 at 6:36 PM
A proof-of-concept trial reported in Nature Medicine shows that the size of circulating tumor cell clusters (which can promote metastatic spread) can be reduced by treatment with the Na+/K+ ATPase inhibitor digoxin in patients with metastatic breast cancer. https://go.nature.com/40sBw6Q #Medsky 🧪
A pretty poison in pink, Digitalis purpurea, the common foxglove is related to the species that is still used to produce digoxin to treat heart conditions. In the correct dose, the drug can strengthen and slow the heartbeat. 💗
#ColorADay #PinkMon #MagentaMonday #BloomScrolling
#ColorADay #PinkMon #MagentaMonday #BloomScrolling
June 8, 2026 at 1:33 PM
A pretty poison in pink, Digitalis purpurea, the common foxglove is related to the species that is still used to produce digoxin to treat heart conditions. In the correct dose, the drug can strengthen and slow the heartbeat. 💗
#ColorADay #PinkMon #MagentaMonday #BloomScrolling
#ColorADay #PinkMon #MagentaMonday #BloomScrolling
Aunt’s new atrial fibrillation drug (on advice of a cardiologist the GP spoke to) is Digoxin
Digitalis!!
A useful & long-used medicinal extract that makes me think of an Agatha Christie novel
Digitalis!!
A useful & long-used medicinal extract that makes me think of an Agatha Christie novel
July 10, 2025 at 3:05 PM
Aunt’s new atrial fibrillation drug (on advice of a cardiologist the GP spoke to) is Digoxin
Digitalis!!
A useful & long-used medicinal extract that makes me think of an Agatha Christie novel
Digitalis!!
A useful & long-used medicinal extract that makes me think of an Agatha Christie novel
Ok, I'm impressed. I can't imagine how long I would have spent stuck on the idea that they meant digoxin.
October 17, 2025 at 7:33 PM
Ok, I'm impressed. I can't imagine how long I would have spent stuck on the idea that they meant digoxin.
It’s like people need a reminder that digoxin and atropine are “plant-based” too
August 7, 2025 at 9:29 PM
It’s like people need a reminder that digoxin and atropine are “plant-based” too
Digitalis is also the source and name of an important cardiac medication, though we manufacture it now instead of extracting it from foxglove.
Digitalis helps hearts and saves lives 💜
en.wikipedia.org/wiki/Digoxin
Digitalis helps hearts and saves lives 💜
en.wikipedia.org/wiki/Digoxin
June 12, 2025 at 7:12 PM
Digitalis is also the source and name of an important cardiac medication, though we manufacture it now instead of extracting it from foxglove.
Digitalis helps hearts and saves lives 💜
en.wikipedia.org/wiki/Digoxin
Digitalis helps hearts and saves lives 💜
en.wikipedia.org/wiki/Digoxin
oh my god everyone is on digoxin
May 12, 2025 at 8:09 PM
oh my god everyone is on digoxin
need the digoxin of people
May 17, 2026 at 7:55 PM
need the digoxin of people
Digitalis purpurea. Common foxglove. This flowering plant is growing all over the place. It is the original source for the heart medicine, digoxin. I snapped this photo on our way back down the Brocken.
I have many names,
Lion’s mouth and fairy bells,
Dead men’s bells for sure.
#Photography #Haiku
I have many names,
Lion’s mouth and fairy bells,
Dead men’s bells for sure.
#Photography #Haiku
July 4, 2026 at 11:40 AM
Digitalis purpurea. Common foxglove. This flowering plant is growing all over the place. It is the original source for the heart medicine, digoxin. I snapped this photo on our way back down the Brocken.
I have many names,
Lion’s mouth and fairy bells,
Dead men’s bells for sure.
#Photography #Haiku
I have many names,
Lion’s mouth and fairy bells,
Dead men’s bells for sure.
#Photography #Haiku
Foxglove plants evolved a mammalian-like cholesterol-to-steroid conversion pathway that synthesized cardenolides by mimicking mammals’ endocrine signaling axis.
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4vr7Ndj
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4vr7Ndj
April 17, 2026 at 9:08 PM
Foxglove plants evolved a mammalian-like cholesterol-to-steroid conversion pathway that synthesized cardenolides by mimicking mammals’ endocrine signaling axis.
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4vr7Ndj
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4vr7Ndj
March 20, 2025 at 4:54 AM
A drug that limits the clustering of malignant breast-cancer cells that are moving through the bloodstream to distant organs might open avenues to block the lethal spread of a tumour
https://go.nature.com/4gmTQE9
https://go.nature.com/4gmTQE9
Breaking up clusters of circulating tumour cells to halt cancer spread
The drug digoxin reduces the clustering of tumour cells.
go.nature.com
January 28, 2025 at 1:40 PM
A drug that limits the clustering of malignant breast-cancer cells that are moving through the bloodstream to distant organs might open avenues to block the lethal spread of a tumour
https://go.nature.com/4gmTQE9
https://go.nature.com/4gmTQE9
#plants #history #botany #art 🌱
Digitalis purpurea - Common Foxglove
Original source of the cardiac #medicine Digoxin / Digitalin.
First clues from William Withering in 1785 who used it to treat Dropsy. Digoxin was isolated c1930 by Dr Sydney Smith.
General ref:
en.wikipedia.org/wiki/Digitalis
Digitalis purpurea - Common Foxglove
Original source of the cardiac #medicine Digoxin / Digitalin.
First clues from William Withering in 1785 who used it to treat Dropsy. Digoxin was isolated c1930 by Dr Sydney Smith.
General ref:
en.wikipedia.org/wiki/Digitalis
November 17, 2025 at 12:22 AM
