For #FluorescenceFriday - me on the server snooping on progress for experiments for a paper revision... and that's some really nice layering in the dorsolateral prefrontal cortex of the human 🧠🔬🧪👩🔬🤩
February 13, 2026 at 7:00 PM
For #FluorescenceFriday - me on the server snooping on progress for experiments for a paper revision... and that's some really nice layering in the dorsolateral prefrontal cortex of the human 🧠🔬🧪👩🔬🤩
February 19, 2026 at 2:11 AM
In the forests of Southern Madagascar, three frog species were discovered in 2019 that represent the very lower limit of vertebrate size: < 9 mm long.
The genus was named "Mini", and the three species are:
Mini mum
Mini ature
Mini scule
(scientists are nerds, okay?)
The genus was named "Mini", and the three species are:
Mini mum
Mini ature
Mini scule
(scientists are nerds, okay?)
January 26, 2025 at 5:28 PM
In the forests of Southern Madagascar, three frog species were discovered in 2019 that represent the very lower limit of vertebrate size: < 9 mm long.
The genus was named "Mini", and the three species are:
Mini mum
Mini ature
Mini scule
(scientists are nerds, okay?)
The genus was named "Mini", and the three species are:
Mini mum
Mini ature
Mini scule
(scientists are nerds, okay?)
🧠 Brain stimulation & depression
A new study in marmosets shows that dysfunction in dorsolateral prefrontal area 46 lowers motivation & heightens anxiety
Ketamine reversed motivational loss, offering insight into how brain stimulation may treat depression
🔗 doi.org/10.1126/scie...
#SciComm 🧪
A new study in marmosets shows that dysfunction in dorsolateral prefrontal area 46 lowers motivation & heightens anxiety
Ketamine reversed motivational loss, offering insight into how brain stimulation may treat depression
🔗 doi.org/10.1126/scie...
#SciComm 🧪
Dysfunction in primate dorsolateral prefrontal area 46 affects motivation and anxiety
The dorsolateral prefrontal cortex (dlPFC) is a higher-order brain structure targeted for noninvasive stimulation for treatment-resistant depression. Nonetheless, its causal role in emotion regulation...
doi.org
August 25, 2025 at 6:49 AM
🧠 Brain stimulation & depression
A new study in marmosets shows that dysfunction in dorsolateral prefrontal area 46 lowers motivation & heightens anxiety
Ketamine reversed motivational loss, offering insight into how brain stimulation may treat depression
🔗 doi.org/10.1126/scie...
#SciComm 🧪
A new study in marmosets shows that dysfunction in dorsolateral prefrontal area 46 lowers motivation & heightens anxiety
Ketamine reversed motivational loss, offering insight into how brain stimulation may treat depression
🔗 doi.org/10.1126/scie...
#SciComm 🧪
Really delighted to share our new article in Current Biology showing that the cingulate-to-dorsolateral prefrontal pathway is not involved in trial-to-trial short-term adaptation but rather in sustained motivational control.
doi.org/10.1016/j.cu...
doi.org/10.1016/j.cu...
Redirecting
doi.org
November 2, 2025 at 12:52 PM
Really delighted to share our new article in Current Biology showing that the cingulate-to-dorsolateral prefrontal pathway is not involved in trial-to-trial short-term adaptation but rather in sustained motivational control.
doi.org/10.1016/j.cu...
doi.org/10.1016/j.cu...
"show me where this dorsolateral prefrontal activation is in a mouse brain"
September 17, 2026 at 12:40 PM
"show me where this dorsolateral prefrontal activation is in a mouse brain"
Cell Type Specific Enhancers for Dorsolateral Prefrontal Cortex. https://www.biorxiv.org/content/10.1101/2024.12.01.626253v1
Cell Type Specific Enhancers for Dorsolateral Prefrontal Cortex. https://www.biorxiv.org/content/10.1101/2024.12.01.626253v1
The dorsolateral prefrontal cortex (DLPFC) is crucial to primate cognitive functions, but a paucity
www.biorxiv.org
December 2, 2024 at 9:15 AM
Cell Type Specific Enhancers for Dorsolateral Prefrontal Cortex. https://www.biorxiv.org/content/10.1101/2024.12.01.626253v1
White matter pathways mediating dorsolateral prefrontal TMS therapy for depression
New @natneuro.nature.com paper led by Caio Seguin, Robin Cash, and Andrew Zalesky.
We map (indirect) pathways from DLPFC to SGC and link individual variation with response efficacy.
www.nature.com/articles/s41...
New @natneuro.nature.com paper led by Caio Seguin, Robin Cash, and Andrew Zalesky.
We map (indirect) pathways from DLPFC to SGC and link individual variation with response efficacy.
www.nature.com/articles/s41...
White matter pathways mediating dorsolateral prefrontal TMS therapy for depression - Nature Neuroscience
Seguin et al. show that the efficacy of transcranial magnetic stimulation for depression depends on how stimulation spreads through the brain’s wiring. Patients with shorter communication pathways bet...
www.nature.com
April 14, 2026 at 4:37 PM
White matter pathways mediating dorsolateral prefrontal TMS therapy for depression
New @natneuro.nature.com paper led by Caio Seguin, Robin Cash, and Andrew Zalesky.
We map (indirect) pathways from DLPFC to SGC and link individual variation with response efficacy.
www.nature.com/articles/s41...
New @natneuro.nature.com paper led by Caio Seguin, Robin Cash, and Andrew Zalesky.
We map (indirect) pathways from DLPFC to SGC and link individual variation with response efficacy.
www.nature.com/articles/s41...
Recurrent activity propagates through labile ensembles in macaque dorsolateral prefrontal microcircuits
www.cell.com/current-biol...
#neuroscience
www.cell.com/current-biol...
#neuroscience
Recurrent activity propagates through labile ensembles in macaque dorsolateral prefrontal microcircuits
Using ex vivo Ca2+ imaging in macaque dorsolateral prefrontal cortex, Nolan et al. reveal that recurrent activity propagates through unstable, stochastically assembled ensembles to produce stable population-level events. Network excitability covaried with set-shifting performance, suggesting that these features may underlie dlPFC’s role in cognition.
www.cell.com
January 9, 2025 at 12:56 PM
Recurrent activity propagates through labile ensembles in macaque dorsolateral prefrontal microcircuits
www.cell.com/current-biol...
#neuroscience
www.cell.com/current-biol...
#neuroscience
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorders, and offers potential targets for therapeutic intervention.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Single-cell atlas of transcriptomic vulnerability across brain disorders - Nature
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorde...
www.nature.com
September 25, 2026 at 1:19 AM
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorders, and offers potential targets for therapeutic intervention.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
March 5, 2026 at 1:51 AM
Nature research paper: Single-cell atlas of transcriptomic vulnerability across brain disorders
go.nature.com/4dxeB1u
go.nature.com/4dxeB1u
Single-cell atlas of transcriptomic vulnerability across brain disorders - Nature
A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorders, and offers potential targets for therapeutic intervention.
go.nature.com
September 27, 2026 at 1:02 PM
Nature research paper: Single-cell atlas of transcriptomic vulnerability across brain disorders
go.nature.com/4dxeB1u
go.nature.com/4dxeB1u
Why does this look NSFW? or have I just been corrupted by all of you?
May 28, 2025 at 10:23 AM
Why does this look NSFW? or have I just been corrupted by all of you?
Frog survey training! #CommunityScience 🐸🐸🐸
January 31, 2026 at 7:39 PM
Frog survey training! #CommunityScience 🐸🐸🐸
Consciousness and the brain
So strange that dorsolateral PFC is not there.
What are ventrotemporal and inferior frontal cortex doing there, especially ventrotemporal, very strange... 😅
Maybe we can organize an online discussion via the Neuroscience and Philosophy Salon!
So strange that dorsolateral PFC is not there.
What are ventrotemporal and inferior frontal cortex doing there, especially ventrotemporal, very strange... 😅
Maybe we can organize an online discussion via the Neuroscience and Philosophy Salon!
April 30, 2025 at 3:21 PM
Consciousness and the brain
So strange that dorsolateral PFC is not there.
What are ventrotemporal and inferior frontal cortex doing there, especially ventrotemporal, very strange... 😅
Maybe we can organize an online discussion via the Neuroscience and Philosophy Salon!
So strange that dorsolateral PFC is not there.
What are ventrotemporal and inferior frontal cortex doing there, especially ventrotemporal, very strange... 😅
Maybe we can organize an online discussion via the Neuroscience and Philosophy Salon!
Green Frogs are mid-sized frogs with prominent ridges of skin extending down the back. They are commonly found in wetlands. Green Frog, Essex County, NY (17 May 2024). wildadirondacks.org/adirondack-a...
#greenfrog #herps #nature #photography #naturalist #wildlife #naturephotography #wetlands
#greenfrog #herps #nature #photography #naturalist #wildlife #naturephotography #wetlands
January 5, 2025 at 11:07 PM
Green Frogs are mid-sized frogs with prominent ridges of skin extending down the back. They are commonly found in wetlands. Green Frog, Essex County, NY (17 May 2024). wildadirondacks.org/adirondack-a...
#greenfrog #herps #nature #photography #naturalist #wildlife #naturephotography #wetlands
#greenfrog #herps #nature #photography #naturalist #wildlife #naturephotography #wetlands
In the truest expression of #InverteFest as seeking out what lives near you, this Xenox fly was on the side of one of my plant pots
August 28, 2026 at 11:45 AM
In the truest expression of #InverteFest as seeking out what lives near you, this Xenox fly was on the side of one of my plant pots
Night surveys were also productive. Have you ever seen a more gorgeous California red-legged frog? *handled with all appropriate permits* #herps #crlf #redleggedfrog #frogs #fieldbiologist
March 10, 2025 at 6:56 AM
Night surveys were also productive. Have you ever seen a more gorgeous California red-legged frog? *handled with all appropriate permits* #herps #crlf #redleggedfrog #frogs #fieldbiologist
#Medsky🧪 #IDsky #neurosky #neurocovid #publichealth
Evidence suggests that #neuroinflammation in the dorsolateral inferior medulla is a possible CNS localisation for POTS & #LongCOVID. Both conditions are complex, multi-systemic disorders
Evidence suggests that #neuroinflammation in the dorsolateral inferior medulla is a possible CNS localisation for POTS & #LongCOVID. Both conditions are complex, multi-systemic disorders
🧠 Daily Feed of Brain Damage 🧠
With thanks to my wonderful WHN Long C-19 Groupie, Svetlana Blitsheyn
doi.org/10.3390/biom...
With thanks to my wonderful WHN Long C-19 Groupie, Svetlana Blitsheyn
doi.org/10.3390/biom...
doi.org
September 18, 2025 at 12:31 PM
#Medsky🧪 #IDsky #neurosky #neurocovid #publichealth
Evidence suggests that #neuroinflammation in the dorsolateral inferior medulla is a possible CNS localisation for POTS & #LongCOVID. Both conditions are complex, multi-systemic disorders
Evidence suggests that #neuroinflammation in the dorsolateral inferior medulla is a possible CNS localisation for POTS & #LongCOVID. Both conditions are complex, multi-systemic disorders
Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🌎🍽️
Very happy to finally share a major update in our work exploring the hippocampus and lateral septum in calibrating food consumption! 🍩
Major thanks to our lab and collaborators! ⭐️⭐️
www.cell.com/neuron/fullt...
Very happy to finally share a major update in our work exploring the hippocampus and lateral septum in calibrating food consumption! 🍩
Major thanks to our lab and collaborators! ⭐️⭐️
www.cell.com/neuron/fullt...
A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding
Goode et al. show that prodynorphin (Pdyn)-expressing neurons of the dorsolateral
septum (DLS) receive substantial dorsal hippocampal (DHPC) input and inhibit lateral
hypothalamic (LHA) GABAergic neur...
www.cell.com
February 12, 2026 at 10:04 PM
Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🌎🍽️
Very happy to finally share a major update in our work exploring the hippocampus and lateral septum in calibrating food consumption! 🍩
Major thanks to our lab and collaborators! ⭐️⭐️
www.cell.com/neuron/fullt...
Very happy to finally share a major update in our work exploring the hippocampus and lateral septum in calibrating food consumption! 🍩
Major thanks to our lab and collaborators! ⭐️⭐️
www.cell.com/neuron/fullt...
#Sleep deprivation weakens the brain's ability to suppress unwanted thoughts and memories:
pubmed.ncbi.nlm.nih.gov/39739795
How? REM sleep strengthened inhibitory control of the right dorsolateral prefrontal cortex in new imaging study.
#psychology #psychiatry #science #mentalhealth
pubmed.ncbi.nlm.nih.gov/39739795
How? REM sleep strengthened inhibitory control of the right dorsolateral prefrontal cortex in new imaging study.
#psychology #psychiatry #science #mentalhealth
January 18, 2025 at 11:54 PM
#Sleep deprivation weakens the brain's ability to suppress unwanted thoughts and memories:
pubmed.ncbi.nlm.nih.gov/39739795
How? REM sleep strengthened inhibitory control of the right dorsolateral prefrontal cortex in new imaging study.
#psychology #psychiatry #science #mentalhealth
pubmed.ncbi.nlm.nih.gov/39739795
How? REM sleep strengthened inhibitory control of the right dorsolateral prefrontal cortex in new imaging study.
#psychology #psychiatry #science #mentalhealth
July 31, 2026 at 11:55 PM