Our new paper is online and describes how antibiotic treatment #AMR versus osmotive laxative pre-exposure alters the gut environment leading to different colonization outcomes and evolutionary fates of hypervirulent #Klebsiella pneumoniae!
onlinelibrary.wiley.com/share/CJFYDB...
#Microsky #UTIsky
onlinelibrary.wiley.com/share/CJFYDB...
#Microsky #UTIsky
Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae
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onlinelibrary.wiley.com
September 24, 2026 at 10:40 AM
Our new paper is online and describes how antibiotic treatment #AMR versus osmotive laxative pre-exposure alters the gut environment leading to different colonization outcomes and evolutionary fates of hypervirulent #Klebsiella pneumoniae!
onlinelibrary.wiley.com/share/CJFYDB...
#Microsky #UTIsky
onlinelibrary.wiley.com/share/CJFYDB...
#Microsky #UTIsky
Imbalance in gut microbial interactions as a marker of health and disease
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
February 27, 2026 at 8:13 AM
Imbalance in gut microbial interactions as a marker of health and disease
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Glad to have been part of this new paper, showing how the gut microbiomes of people with a wide range of diseases shift from being dominated by competitive interactions between microbes to being dominated by cross-feeding interactions (1/2) www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
February 26, 2026 at 10:08 PM
Glad to have been part of this new paper, showing how the gut microbiomes of people with a wide range of diseases shift from being dominated by competitive interactions between microbes to being dominated by cross-feeding interactions (1/2) www.science.org/doi/10.1126/...
Microbes, Ecology And Medicine - Dr. Sean M. Gibbons, Ph.D. - Associate Professor, Institute for Systems Biology , joins me on Progress, Potential, And Possibilities #SeanGibbons #InstituteForSystemsBiology #Microbiome #Microbes #Ecology #Medicine #Dysbioses - www.youtube.com/watch?v=OeSc...
Dr. Sean Gibbons, Ph.D. - Institute for Systems Biology (ISB) - Microbes, Ecology And Medicine
YouTube video by Progress, Potential, and Possibilities
www.youtube.com
February 26, 2025 at 8:55 PM
Microbes, Ecology And Medicine - Dr. Sean M. Gibbons, Ph.D. - Associate Professor, Institute for Systems Biology , joins me on Progress, Potential, And Possibilities #SeanGibbons #InstituteForSystemsBiology #Microbiome #Microbes #Ecology #Medicine #Dysbioses - www.youtube.com/watch?v=OeSc...
Researchers reanalyzed microbiome data and built a metabolic model showing dysbiosis shifts the gut from competitive bacteria to cooperative cross feeding networks.
This rising cooperation may signal disease progression and offer an early warning marker.
www.science.org/doi/10.1126/...
This rising cooperation may signal disease progression and offer an early warning marker.
www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
February 26, 2026 at 8:56 PM
Researchers reanalyzed microbiome data and built a metabolic model showing dysbiosis shifts the gut from competitive bacteria to cooperative cross feeding networks.
This rising cooperation may signal disease progression and offer an early warning marker.
www.science.org/doi/10.1126/...
This rising cooperation may signal disease progression and offer an early warning marker.
www.science.org/doi/10.1126/...
Ya'll microbiologists better watch out ⚠️
THE Simon Levin just dipped his toe into addressing problems in microbiome dynamics & characterizing dysbioses
A legendary problem-solver has just stepped into the ring
THE Simon Levin just dipped his toe into addressing problems in microbiome dynamics & characterizing dysbioses
A legendary problem-solver has just stepped into the ring
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome (dysbioses) are linked to multiple diseases but remain poorly understood. Current biomarkers to identify dysbiosis are inconsistent and fail to capture the ecolo...
doi.org
June 11, 2025 at 1:24 PM
Ya'll microbiologists better watch out ⚠️
THE Simon Levin just dipped his toe into addressing problems in microbiome dynamics & characterizing dysbioses
A legendary problem-solver has just stepped into the ring
THE Simon Levin just dipped his toe into addressing problems in microbiome dynamics & characterizing dysbioses
A legendary problem-solver has just stepped into the ring
Not what I expected: increase in inter species feeding cooperativity is an indicator of many diseases
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
March 12, 2026 at 2:43 AM
Not what I expected: increase in inter species feeding cooperativity is an indicator of many diseases
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease | Science www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
February 26, 2026 at 10:17 PM
Imbalance in gut microbial interactions as a marker of health and disease | Science www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
March 4, 2026 at 8:51 AM
Imbalance in gut microbial interactions as a marker of health and disease www.science.org/doi/10.1126/...
Grâce à un modèle écologique, une étude montre que les microbiotes sains reposent surtout sur la compétition. Un nouvel indicateur, l’ENBI, capable de distinguer santé et maladie, et même d’en prédire la gravité, est proposé par ces chercheurs
#science
www.science.org/doi/10.1126/...
#science
www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
April 13, 2026 at 3:29 PM
Grâce à un modèle écologique, une étude montre que les microbiotes sains reposent surtout sur la compétition. Un nouvel indicateur, l’ENBI, capable de distinguer santé et maladie, et même d’en prédire la gravité, est proposé par ces chercheurs
#science
www.science.org/doi/10.1126/...
#science
www.science.org/doi/10.1126/...
Le microbiome cervico-vaginal pourrait jouer un rôle protecteur contre le cancer de la prostate (chez l’homme)
Le microbiome cervico-vaginal pourrait jouer un rôle protecteur contre le cancer de la prostate (chez l’homme)
Un court commentaire de Philippe Charlier, médecin, paléopathologiste et directeur du Laboratoire anthropologie, archéologie, biologie (Laab – Univ. Paris-Saclay/UVSQ), paru dans Medical Hypotheses, s’appuie sur des études épidémiologiques et microbiologiques démontrant que les déséquilibres du microbiote (ou dysbioses) favorisent l’inflammation chronique, un facteur reconnu de cancérogenèse.
Le microbiome vaginal sain, dominé par les Lactobacillus (notamment L. crispatus), maintient un pH acide et empêche la colonisation par des agents pathogènes. Cette stabilité réduit la transmission des infections sexuellement transmissibles et l’inflammation génitale. L’auteur émet l’hypothèse que l’exposition régulière du pénis à un microbiote vaginal équilibré, lors de rapports hétérosexuels, pourrait protéger la prostate des infections et de l’inflammation à long terme. En revanche, la masturbation, qui ne permet pas cet échange microbiotique, ne présenterait pas les mêmes effets bénéfiques.
Cette différence pourrait expliquer pourquoi une activité sexuelle partagée semble plus protectrice contre le cancer prostatique que l’éjaculation seule. L’article évoque également les modifications du microbiote vaginal à la ménopause, susceptibles d’augmenter le risque d’infection prostatique chez les partenaires masculins.
Enfin, l’auteur suggère d’explorer les effets inverses, c’est-à-dire l’impact du microbiote masculin sur la santé gynécologique féminine. Il conclut que le rôle du microbiome dans la santé sexuelle et reproductive constitue un champ majeur de recherche en santé publique.
-> Contact : philippe.charlier@uvsq.fr
sco.lt
October 17, 2025 at 9:57 PM
Le microbiome cervico-vaginal pourrait jouer un rôle protecteur contre le cancer de la prostate (chez l’homme)
RAPPEL ! Appels à candidatures Tech Transfer de la SATT Paris-Saclay
RAPPEL ! Appels à candidatures Tech Transfer de la SATT Paris-Saclay
CHERCHEURS DE PARIS-SACLAY,
TRANSFÉREZ VOS TECHNOLOGIES !
📢 3 projets finalistes sur 7 projets candidats de l’appel à candidatures du 10 juin 2025 !
Ces projets couvrent différents domaines :
► Traplan en Thérapie Innovante en Oncologie
► Prébiosyme pour le Traitement des dysbioses intestinales
► VsBias en Plateforme modulaire pour IA
📌 Pour celles et ceux qui n’ont pas pu candidater, un second appel est ouvert avec une clôture au 17 septembre 2025 !
Pour rappel le Tech Transfer Program offre à ses lauréats :
💰 Un investissement entre 130k€ et 500k€
👩💻 Un accompagnement de 18 à 24 mois par les experts-innovation de la SATT.
En savoir plus
sco.lt
September 6, 2025 at 8:49 PM
RAPPEL ! Appels à candidatures Tech Transfer de la SATT Paris-Saclay
Appels à candidatures Tech Transfer de la SATT Paris-Saclay
Appels à candidatures Tech Transfer de la SATT Paris-Saclay
CHERCHEURS DE PARIS-SACLAY,
TRANSFÉREZ VOS TECHNOLOGIES !
📢 3 projets finalistes sur 7 projets candidats de l’appel à candidatures du 10 juin 2025 !
Ces projets couvrent différents domaines :
► Traplan en Thérapie Innovante en Oncologie
► Prébiosyme pour le Traitement des dysbioses intestinales
► VsBias en Plateforme modulaire pour IA
📌 Pour celles et ceux qui n’ont pas pu candidater, un second appel est ouvert avec une clôture au 17 septembre 2025 !
Pour rappel le Tech Transfer Program offre à ses lauréats :
💰 Un investissement entre 130k€ et 500k€
👩💻 Un accompagnement de 18 à 24 mois par les experts-innovation de la SATT.
En savoir plus
sco.lt
August 5, 2025 at 8:36 PM
Appels à candidatures Tech Transfer de la SATT Paris-Saclay
Imbalance in gut microbial interactions as a marker of health and disease www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
February 27, 2026 at 4:57 PM
Imbalance in gut microbial interactions as a marker of health and disease www.science.org/doi/10.1126/...
(5/) …leading to an increase in these micro-organisms, whether fungi such as Candida or bacteria.
Clearly if you have these dysbioses you have to decrease the outbreaks with antifungals and antibiotics, as they cause outbreaks of symptoms and further decrease immunity. But they will continue to …
Clearly if you have these dysbioses you have to decrease the outbreaks with antifungals and antibiotics, as they cause outbreaks of symptoms and further decrease immunity. But they will continue to …
October 24, 2023 at 4:03 PM
(5/) …leading to an increase in these micro-organisms, whether fungi such as Candida or bacteria.
Clearly if you have these dysbioses you have to decrease the outbreaks with antifungals and antibiotics, as they cause outbreaks of symptoms and further decrease immunity. But they will continue to …
Clearly if you have these dysbioses you have to decrease the outbreaks with antifungals and antibiotics, as they cause outbreaks of symptoms and further decrease immunity. But they will continue to …
Imbalance in gut microbial interactions as a marker of health and disease | Science
Imbalance in gut microbial interactions as a marker of health and disease | Science
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms that differentiate healthy from diseased microbiomes. We ...
www.science.org
February 26, 2026 at 7:57 PM
Imbalance in gut microbial interactions as a marker of health and disease | Science
Imbalance in gut microbial interactions as a marker of health and disease
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
February 27, 2026 at 1:01 PM
Imbalance in gut microbial interactions as a marker of health and disease
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease | Science www.science.org/doi/10.1126/...
Imbalance in gut microbial interactions as a marker of health and disease
Imbalances in the human gut microbiome, or dysbioses, are associated with multiple diseases but remain poorly understood. Existing biomarkers of dysbiosis fail to capture the ecological mechanisms tha...
www.science.org
March 2, 2026 at 3:09 PM
Imbalance in gut microbial interactions as a marker of health and disease | Science www.science.org/doi/10.1126/...