#ENSARTINIB
Could adjuvant ensartinib change the treatment landscape for resected ALK-positive #NSCLC?

New phase 3 ELEVATE trial results published in NEJM highlight improved disease-free survival after surgery.

🔗 https://ow.ly/8RmT50ZvHE7

#LungCancer #Oncology
Postsurgical Ensartinib in ALK-Positive NSCLC
Adjuvant ensartinib may represent a new therapeutic strategy in completely resected disease.
ow.ly
August 4, 2026 at 2:05 PM
More patients alive and cancer-free at 2 years — adjuvant ensartinib beats placebo in resected ALK+ #NSCLC 🫁
REGISTER to Get the full Newsletter 👉 buff.ly/X6N7qLU or buff.ly/4xd4naf
July 16, 2026 at 10:28 AM
In resected 𝘈𝘓𝘒-positive non–small-cell lung cancer, treatment with ensartinib, a second-generation ALK inhibitor, led to higher disease-free survival than placebo. Learn more about the ELEVATE trial in a short Quick Take video: https://nej.md/4f3LD9u
July 11, 2026 at 10:39 PM
Among patients with resected 𝘈𝘓𝘒-positive non–small-cell lung cancer, 2-year disease-free survival was higher with the ALK inhibitor ensartinib than with placebo. Grade 3 adverse events were more frequent with ensartinib. Full results of the ELEVATE trial: https://nej.md/4wsDQZS
July 10, 2026 at 10:44 PM
Ensartinib in Resected ALK-Positive Non–Small-Cell Lung Cancer

www.nejm.org/doi/full/10....

In this phase 3 trial, 274 patients with completely resected ALK-positive stage IB–IIIB #NSCLC #LungCancer received ensartinib or placebo after adjuvant chemotherapy. Ensartinib 🧪 improved DFS
July 10, 2026 at 9:30 AM
Phase 3 ELEVATE data show that adjuvant ensartinib significantly improved disease-free survival vs placebo in resected ALK-positive NSCLC. @nejm.org #lcsm #oncology

www.onclive.com/view/ensarti...
Ensartinib Reduces Recurrence Risk After Resection in ALK-Positive NSCLC | OncLive
Phase 3 ELEVATE data show that adjuvant ensartinib significantly improved disease-free survival vs placebo in resected ALK-positive NSCLC.
www.onclive.com
July 9, 2026 at 3:53 PM
New in NEJM: The Phase III ELEVATE trial found that adjuvant ensartinib significantly improved disease-free survival after surgery for ALK-positive #lungcancer. Another reminder that biomarker testing is increasingly important in early-stage lung cancer too.

www.nejm.org/doi/full/10.... #LCSM
July 9, 2026 at 2:45 PM
New in NEJM:

Inhaled Treprostinil for Idiopathic Pulmonary Fibrosis (TETON-1 and TETON-2 trials)

Setmelanotide for Acquired Hypothalamic Obesity (TRANSCEND)

Ensartinib after Resection in ALK-Positive NSCLC (ELEVATE)

Explore the issue: https://nej.md/current-issue
July 9, 2026 at 1:00 PM
Ensartinib in Resected ALK

arc-codex.com
July 9, 2026 at 9:49 AM
[3/3] treatment of anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) during IBIIIB (T3N2M0) with ensartinib hydrochloride capsules (trade name: Bemena®) was published in full online in the New England Journal of Medicine.
July 9, 2026 at 12:20 AM
[1/3] 2026-07-09 08:15:44 - [Morning Announcement: The clinical research results of Betta Pharmaceuticals' ensartinib postoperative adjuvant treatment were published in the "New England Journal of Medicine"] ① Pathfinder: The application for issuance of stocks to specific objects was
July 9, 2026 at 12:20 AM
Among patients with resected ALK-positive non–small-cell lung cancer, 2-year disease-free survival was higher with the ALK inhibitor ensartinib than with placebo. Grade 3 adverse events were more frequent with ensartinib. Full ELEVATE trial results: https://nej.md/4wsDQZS
July 8, 2026 at 10:14 PM
[2/2] and Eversana, a global commercialization service provider, have reached a cooperation to jointly promote the commercial expansion of ensacove® (ensartinib hydrochloride capsules, referred to as "ensartinib") in the U.S. market.
April 17, 2026 at 8:30 AM
[1/2] 2026-04-17 16:15:34 - [Xcovery Holdings, Inc., a subsidiary of Beida Pharmaceutical Holdings, and Eversana Company of the United States have reached a commercialization cooperation for ensartinib] Recently, Xcovery Holdings, Inc., a subsidiary of Beida Pharmaceutical Holdings,
April 17, 2026 at 8:30 AM
This 🆕 review by Eric K Singhi & Eric S Nadler brings together long term trial data on first line ALK+ #LungCancer drugs & why early treatment choice can influence what comes next.

UK note: alectinib & lorlatinib are available here. Ensartinib is not.

link.springer.com/epdf/10.1007...

#LCSM
January 28, 2026 at 7:02 PM
A new systematic review looks at 5 ensartinib trials in ALK+ #lungcancer.
It points to good response rates & generally tolerable side-effect profile, but the evidence is still early - most studies were open-label & we still need long-term data & comparisons with newer TKIs.

PubMed: 41148187 #LCSM
November 13, 2025 at 11:04 PM
Feed: "Clinical Trials Arena"
By: GlobalData Healthcare on Thursday, October 23, 2025
ESMO 2025: potential new adjuvant option ensartinib for ALK+ NSCLC
86.4% of patients treated with ensartinib reached 24-month disease-free survival, compared to 53.5% in the placebo control arm.
www.clinicaltrialsarena.com
October 23, 2025 at 12:51 PM
Adjuvant ensartinib improves disease-free survival compared to placebo following complete resection of ALK-positive NSCLC, according to research presented at #ESMO25. #lcsm #ESMO2025

shorturl.at/XHWQh
October 21, 2025 at 2:52 PM
At #MLS_DC25 in Washington, a session on ALK TKIs showed how the field has moved from crizotinib in 2013 to ensartinib in 2025.

Choosing first-line therapy depends on efficacy, safety, and patient factors - there’s no one-size-fits-all in ALK+ #LungCancer

#LCSM
September 27, 2025 at 8:44 PM