#EntorhinalCortex
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plosbiology.org
During task performance, the brain must integrate information re goal-related objects with contextual details. This study shows that participants' performance on a #SpatialNavigation task is related to syncing of activity between #hippocampus & #EntorhinalCortex @plosbiology.org 🧪 plos.io/3Vrw8id
Top: Context representations in hippocampus (HC). Left: The positions of HC electrodes projected onto the MNI152 template from all 25 participants. The red dots are task-selective electrodes (N = 155). The black dots are non-task-selective electrodes (N = 33). Right: A schematic illustration of RSA of HC context representations. Bottom: Object representations in entorhinal cortex (EC). Left: The positions of EC electrodes projected onto the MNI152 template from all 11 participants. The red dots are task-selective electrodes (N = 23). The black dots are non-task-selective electrodes (N = 5). Right: A schematic illustration of EC object representations.
September 22, 2025 at 7:54 AM
plosbiology.org
How do we navigate our #memory maps of spatial & non-spatial experience? This study shows that the #EntorhinalCortex not only encodes the structure of experience, but also actions in conceptual space, and these representations are reflected in #gaze behavior @plosbiology.org 🧪 plos.io/4czCPHk
Experimental design. Top left: Representations of (conceptual) space may benefit from the integration of action affordances, e.g., in a game of chess, where information about how pieces can move is necessary to play the game. The authors tested this idea using numerical operations, whereby participants moved between numbers following the rules of an underlying graph structure. Top right: Participants learned how numbers may ‘transform’ into other numbers using an exploration task, whereby they were presented with an individual number and were offered a free choice of two possible successors. When a successor was chosen, the next trial offered the successors for the chosen number. In interleaved test blocks, participants indicated which were the ‘correct’ successors for each number. In the eyetracker and fMRI scanner, individual numbers were presented in a pseudorandom order. Bottom: Unbeknownst to participants, number-action bindings formed part of a repeating sequence arranged in graph ‘modules’ of four numbers. This can be seen as a set of four states with the same action affordances, projected on a number line. In the example presented, numbers 21 and 26 correspond to state 1 (‘S1’; and therefore also 31, 36, etc.), but this was assigned differently to each participant. As the modules repeated every five numbers, the structure allowed easy inference of action possibilities for any new numbers.
April 15, 2026 at 4:30 PM
plosbiology.org
During task performance, the brain must integrate information re goal-related objects with contextual details. This study shows that participants' performance on a #SpatialNavigation task is related to syncing of activity between #hippocampus & #EntorhinalCortex @plosbiology.org 🧪 plos.io/3Vrw8id
Top: Context representations in hippocampus (HC). Left: The positions of HC electrodes projected onto the MNI152 template from all 25 participants. The red dots are task-selective electrodes (N = 155). The black dots are non-task-selective electrodes (N = 33). Right: A schematic illustration of RSA of HC context representations. Bottom: Object representations in entorhinal cortex (EC). Left: The positions of EC electrodes projected onto the MNI152 template from all 11 participants. The red dots are task-selective electrodes (N = 23). The black dots are non-task-selective electrodes (N = 5). Right: A schematic illustration of EC object representations.
September 22, 2025 at 4:45 PM
plosbiology.org
During task performance, the brain must integrate information re goal-related objects with contextual details. This study shows that participants' performance on a #SpatialNavigation task is related to syncing of activity between #hippocampus & #EntorhinalCortex @plosbiology.org 🧪 plos.io/3Vrw8id
Top: Context representations in hippocampus (HC). Left: The positions of HC electrodes projected onto the MNI152 template from all 25 participants. The red dots are task-selective electrodes (N = 155). The black dots are non-task-selective electrodes (N = 33). Right: A schematic illustration of RSA of HC context representations. Bottom: Object representations in entorhinal cortex (EC). Left: The positions of EC electrodes projected onto the MNI152 template from all 11 participants. The red dots are task-selective electrodes (N = 23). The black dots are non-task-selective electrodes (N = 5). Right: A schematic illustration of EC object representations.
September 22, 2025 at 1:53 PM
plosbiology.org
How do we navigate our #memory maps of spatial & non-spatial experience? This study shows that the #EntorhinalCortex not only encodes the structure of experience, but also actions in conceptual space, and these representations are reflected in #gaze behavior @plosbiology.org 🧪 plos.io/4czCPHk
Experimental design. Top left: Representations of (conceptual) space may benefit from the integration of action affordances, e.g., in a game of chess, where information about how pieces can move is necessary to play the game. The authors tested this idea using numerical operations, whereby participants moved between numbers following the rules of an underlying graph structure. Top right: Participants learned how numbers may ‘transform’ into other numbers using an exploration task, whereby they were presented with an individual number and were offered a free choice of two possible successors. When a successor was chosen, the next trial offered the successors for the chosen number. In interleaved test blocks, participants indicated which were the ‘correct’ successors for each number. In the eyetracker and fMRI scanner, individual numbers were presented in a pseudorandom order. Bottom: Unbeknownst to participants, number-action bindings formed part of a repeating sequence arranged in graph ‘modules’ of four numbers. This can be seen as a set of four states with the same action affordances, projected on a number line. In the example presented, numbers 21 and 26 correspond to state 1 (‘S1’; and therefore also 31, 36, etc.), but this was assigned differently to each participant. As the modules repeated every five numbers, the structure allowed easy inference of action possibilities for any new numbers.
April 15, 2026 at 1:00 PM
plosbiology.org
How do we navigate our #memory maps of spatial & non-spatial experience? This study shows that the #EntorhinalCortex not only encodes the structure of experience, but also actions in conceptual space, and these representations are reflected in #gaze behavior @plosbiology.org 🧪 plos.io/4czCPHk
Experimental design. Top left: Representations of (conceptual) space may benefit from the integration of action affordances, e.g., in a game of chess, where information about how pieces can move is necessary to play the game. The authors tested this idea using numerical operations, whereby participants moved between numbers following the rules of an underlying graph structure. Top right: Participants learned how numbers may ‘transform’ into other numbers using an exploration task, whereby they were presented with an individual number and were offered a free choice of two possible successors. When a successor was chosen, the next trial offered the successors for the chosen number. In interleaved test blocks, participants indicated which were the ‘correct’ successors for each number. In the eyetracker and fMRI scanner, individual numbers were presented in a pseudorandom order. Bottom: Unbeknownst to participants, number-action bindings formed part of a repeating sequence arranged in graph ‘modules’ of four numbers. This can be seen as a set of four states with the same action affordances, projected on a number line. In the example presented, numbers 21 and 26 correspond to state 1 (‘S1’; and therefore also 31, 36, etc.), but this was assigned differently to each participant. As the modules repeated every five numbers, the structure allowed easy inference of action possibilities for any new numbers.
April 16, 2026 at 7:57 AM