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New Epigenome Technologies Blog post! bit.ly/4aiWY4T

"Can RENDER Move Epigenome Editing Closer to Therapeutic Applications?"

Based on a Nature Communications paper from James K. Nuez (University of California, Berkeley)

#Epigenetics #Blog #EpigenomeTech #EpigenomeEditing #RENDER
December 17, 2025 at 4:41 PM
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Epigenetics Update - Structure-guided discovery and engineering of miniature CRISPR-Cas12m for epigenome editing u.epigenome.us/EH7zr6pD

Kuanhui Xiang, Lin Bai, and Kailong Li (pku1898.bsky.social) in NSMB

#Epigenetics #CRISPR #EpigenomeEditing
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Gain deeper insights; epigenometech.com
Structure-guided discovery and engineering of miniature CRISPR–Cas12m for epigenome editing - Nature Structural & Molecular Biology
The authors identified and engineered a miniature, innate nuclease-dead xCas12m enabling effective epigenome editing. xCas12m–CRISPRoff achieved durable epigenetic silencing and inhibition of hepatitis B virus infection through single-AAV delivery.
u.epigenome.us
September 22, 2026 at 11:26 AM
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📜 Systematic epigenome editing captures the context-dependent instructive function of chromatin modifications

🧑‍🔬 Cristina Policarpi, Jamie A. Hackett, et al.

📔 @natureportfolio.bsky.social Genetics

🔗 www.nature.com/articles/s41...

#️⃣ #Epigenomics #Epigenetics #EpigenomeEditing #GenomeEditing
Systematic epigenome editing captures the context-dependent instructive function of chromatin modifications - Nature Genetics
The authors develop and harness a suite of epigenome editing tools to explore the role of different epigenetic marks in modulating transcription. In particular, H3K4me3 deposition on promoter sequence...
www.nature.com
May 14, 2024 at 6:55 AM
epigenometech.bsky.social
Epigenetics News - Epigenetics on demand to tackle inflammatory diseases bit.ly/3TLQ8v6

Findings take innovative therapies based on epigenome editing closer to tackling inflammatory diseases

#Epigenetics #News #EpigenomeEditing
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Gain deeper insights into gene regulation; epigenometech.com
Epigenetics on demand to tackle inflammatory diseases
Controlling the activity of specific genes in the laboratory through the editing of their epigenetic marks is now a reality thanks to the CRISPR technology. ...
bit.ly
July 24, 2025 at 12:58 PM