m6A RNA methylation #FGF16 #CardiacRegeneration

AAV9-shRNA Mettl3⏫🫀repair in neonate p3 (apex resection), p7 (MI) & 3 mo (MI)

Fgf16 mRNA was destabilized upon m6A (Mettl3-Ythdf2)

AAV9-Fgf16 m6A site mutant (not WT) ⏫neonatal🫀regeneration

@elife.bsky.social 2022
elifesciences.org/articles/77014

A primer for Fibroblast Growth Factor 16 (FGF16)

1⃣Mouse
Brain
Heart
Liver
Testis

2⃣Human
Mutation->skeletal deformity (Metacarpal 4/5 fusion)

3⃣#Zebrafish
Pectoral fin development

#Differentiation 2024
www.sciencedirect.com/science/arti...

Roles of FGF9 & FGF16 in 🐣Intramuscular Fat Deposition?🧐

⏫in primary intramuscular adipocyte by lentiviral FTO/Fat Mass And Obesity Associated, a m6A RNA demethylase

#Cells_MDPI 2026
www.mdpi.com/2073-4409/15...

Possible protective effects of #FGF9 FGF16 (out of 40 cytokines, 307 SNPs) on #IntracranialAneurysm #SubarachnoidHemorrhage

#MendelianRandomization analysis

INTERVAL (3622 plasma proteins, 3301👤)
AGES (2091 plasma proteins, 5368👤)

Eur J Med Res 2024
eurjmedres.biomedcentral.com/articles/10....