Online now: CXCL12-CXCR4 signaling characterizes a targetable fibroblast-lymphocyte niche in pulmonary fibrosis
CXCL12-CXCR4 signaling characterizes a targetable fibroblast-lymphocyte niche in pulmonary fibrosis
Immunology; Cell biology
dlvr.it
November 4, 2026 at 3:08 PM
Online now: CXCL12-CXCR4 signaling characterizes a targetable fibroblast-lymphocyte niche in pulmonary fibrosis
Autoimmune-shared immune states converge in a CXCL12–CXCR4 fibroblast–immune niche in chronic antibody-mediated rejection @sigtrans-sttt.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 3, 2026 at 1:27 AM
Autoimmune-shared immune states converge in a CXCL12–CXCR4 fibroblast–immune niche in chronic antibody-mediated rejection @sigtrans-sttt.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
BHK 21 Hamster Kidney Fibroblast Cells Market | Analysis 2035 | WiseGuyReports www.wiseguyreports.com/reports/bhk-...
BHK 21 Hamster Kidney Fibroblast Cells Market | Analysis 2035
BHK 21 Hamster Kidney Fibroblast Cells Market is Estimated to Grow From USD 800 Billion To USD 1500 Billion by 2035, Reaching at a CAGR of 5.9% During 2026 - 2035
www.wiseguyreports.com
November 2, 2026 at 9:16 AM
BHK 21 Hamster Kidney Fibroblast Cells Market | Analysis 2035 | WiseGuyReports www.wiseguyreports.com/reports/bhk-...
Pathogenic #Keratinocyte States and #Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Du-Harpur et al
https://doi.org/10.1016/j.jid.2026.08.033
#DermatologyJournal #Dermatology #derm #dermatologist #dermresearch #dermscience #HidradenitisSuppurativa
Du-Harpur et al
https://doi.org/10.1016/j.jid.2026.08.033
#DermatologyJournal #Dermatology #derm #dermatologist #dermresearch #dermscience #HidradenitisSuppurativa
November 1, 2026 at 3:15 PM
Pathogenic #Keratinocyte States and #Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Du-Harpur et al
https://doi.org/10.1016/j.jid.2026.08.033
#DermatologyJournal #Dermatology #derm #dermatologist #dermresearch #dermscience #HidradenitisSuppurativa
Du-Harpur et al
https://doi.org/10.1016/j.jid.2026.08.033
#DermatologyJournal #Dermatology #derm #dermatologist #dermresearch #dermscience #HidradenitisSuppurativa
This month's Nature Cell Biology cover: An organoid co-culture system reveals distinct epithelial-fibroblast interactions in pancreatitis versus pancreatic cancer.
Related papers below 👇
Personalise your paper feed at www.thepaperspray.com/bsky
#CancerResearch #Organoids #PancreaticCancer
Related papers below 👇
Personalise your paper feed at www.thepaperspray.com/bsky
#CancerResearch #Organoids #PancreaticCancer
Multi-stromal organoid co-culture modelling reveals epithelial–fibroblast heterogeneity in pancreatic cancer and pancreatitis
Li, Jihad and colleagues develop an organoid co-culture system, alongside patient tissue and mouse model analyses, to model, characterize and compare cellular interactions between epithelia and stroma in pancreatitis versus pancreatic ductal adenocarcinoma.
www.nature.com
October 31, 2026 at 2:01 PM
This month's Nature Cell Biology cover: An organoid co-culture system reveals distinct epithelial-fibroblast interactions in pancreatitis versus pancreatic cancer.
Related papers below 👇
Personalise your paper feed at www.thepaperspray.com/bsky
#CancerResearch #Organoids #PancreaticCancer
Related papers below 👇
Personalise your paper feed at www.thepaperspray.com/bsky
#CancerResearch #Organoids #PancreaticCancer
To read more about this exciting research, please see: pubmed.ncbi.nlm.nih.gov/42893628/
Phasic metabolic remodeling coordinates cardiac myofibroblast differentiation and function - PubMed
Fibroblast differentiation into matrix-producing, contractile myofibroblasts is accompanied by metabolic reprogramming, but whether these changes precede differentiation or arise from the activated ph...
pubmed.ncbi.nlm.nih.gov
November 2, 2026 at 3:00 AM
To read more about this exciting research, please see: pubmed.ncbi.nlm.nih.gov/42893628/
🫀 How do cardiac fibroblasts become fibrosis-driving myofibroblasts? A new study from the Hill lab finds that glycolysis is activated within 1.5 hours of TGFβ stimulation, preceding major transcriptional and phenotypic remodeling. Metabolism emerges as a key regulator of fibroblast fate & function.
November 2, 2026 at 2:59 AM
🫀 How do cardiac fibroblasts become fibrosis-driving myofibroblasts? A new study from the Hill lab finds that glycolysis is activated within 1.5 hours of TGFβ stimulation, preceding major transcriptional and phenotypic remodeling. Metabolism emerges as a key regulator of fibroblast fate & function.
Comparative molecular analysis of histopathologic subtypes reveals shared epithelial remodeling yet distinct fibroblast programs in scleroderma lung disease https://www.biorxiv.org/content/10.64898/2026.11.03.763791v1
November 4, 2026 at 11:31 AM
Comparative molecular analysis of histopathologic subtypes reveals shared epithelial remodeling yet distinct fibroblast programs in scleroderma lung disease https://www.biorxiv.org/content/10.64898/2026.11.03.763791v1
Representation-dependent transportability of single-cell-derived myeloid- and fibroblast/stromal-associated transcriptional programs in bladder cancer #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-11050428/latest
https://www.researchsquare.com/article/rs-11050428/latest
November 2, 2026 at 11:00 PM
Representation-dependent transportability of single-cell-derived myeloid- and fibroblast/stromal-associated transcriptional programs in bladder cancer #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-11050428/latest
https://www.researchsquare.com/article/rs-11050428/latest
Explore the shared immune features in kidney transplant rejection.
Researchers identify a CXCL12–CXCR4 fibroblast–immune niche, linking immune states to inflammation in kidney #Allografts, with related features in #AutoimmuneDiseases.
#STTT #OpenAccess: doi.org/10.1038/s413...
Researchers identify a CXCL12–CXCR4 fibroblast–immune niche, linking immune states to inflammation in kidney #Allografts, with related features in #AutoimmuneDiseases.
#STTT #OpenAccess: doi.org/10.1038/s413...
November 3, 2026 at 6:40 AM
Explore the shared immune features in kidney transplant rejection.
Researchers identify a CXCL12–CXCR4 fibroblast–immune niche, linking immune states to inflammation in kidney #Allografts, with related features in #AutoimmuneDiseases.
#STTT #OpenAccess: doi.org/10.1038/s413...
Researchers identify a CXCL12–CXCR4 fibroblast–immune niche, linking immune states to inflammation in kidney #Allografts, with related features in #AutoimmuneDiseases.
#STTT #OpenAccess: doi.org/10.1038/s413...
Comparative molecular analysis of histopathologic subtypes reveals shared epithelial remodeling yet distinct fibroblast programs in scleroderma lung disease https://www.biorxiv.org/content/10.64898/2026.11.03.763791v1
November 4, 2026 at 11:31 AM
Comparative molecular analysis of histopathologic subtypes reveals shared epithelial remodeling yet distinct fibroblast programs in scleroderma lung disease https://www.biorxiv.org/content/10.64898/2026.11.03.763791v1
Fibroblast activation protein mediates vascular restenosis after surgery for peripheral arterial disease
Fibroblast activation protein mediates vascular restenosis after surgery for peripheral arterial disease
chuckyscarnage.tech.blog
October 30, 2026 at 9:26 AM
Fibroblast activation protein mediates vascular restenosis after surgery for peripheral arterial disease
Integrated Valorisation of Spartium junceum into a Bioactive Cellulose Acetate/Halloysite Nanofibrous Wound Dressing with Sustained Antioxidant Availability and Enhanced Fibroblast Migration #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10821671/latest
https://www.researchsquare.com/article/rs-10821671/latest
November 2, 2026 at 11:02 PM
Integrated Valorisation of Spartium junceum into a Bioactive Cellulose Acetate/Halloysite Nanofibrous Wound Dressing with Sustained Antioxidant Availability and Enhanced Fibroblast Migration #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10821671/latest
https://www.researchsquare.com/article/rs-10821671/latest
Explore the multifaceted roles of #CancerAssociatedFibroblasts in tumor progression and therapeutic resistance.
This review details fibroblast heterogeneity, extracellular matrix remodeling, and reprogramming strategies.
#STTT #OpenAccess: doi.org/10.1038/s413...
This review details fibroblast heterogeneity, extracellular matrix remodeling, and reprogramming strategies.
#STTT #OpenAccess: doi.org/10.1038/s413...
November 4, 2026 at 2:30 AM
Explore the multifaceted roles of #CancerAssociatedFibroblasts in tumor progression and therapeutic resistance.
This review details fibroblast heterogeneity, extracellular matrix remodeling, and reprogramming strategies.
#STTT #OpenAccess: doi.org/10.1038/s413...
This review details fibroblast heterogeneity, extracellular matrix remodeling, and reprogramming strategies.
#STTT #OpenAccess: doi.org/10.1038/s413...
Directed differentiation is strongest when phenotype and function converge. Beyond markers, lineage tracing, barrier properties, surfactant production and single-cell comparison with AT1/AT2 cells would test whether stretch and fibroblast coculture create bipotency rather than transient states.
November 2, 2026 at 6:05 PM
Directed differentiation is strongest when phenotype and function converge. Beyond markers, lineage tracing, barrier properties, surfactant production and single-cell comparison with AT1/AT2 cells would test whether stretch and fibroblast coculture create bipotency rather than transient states.
Related papers from the past week:
• ANO6-mediated trogocytosis of cancer-associated fibroblasts… (Nature Cancer)
• Fibroblast–myeloid stromal crosstalk is associated with cli… (The Journal of Pathology)
• Complement in cancer-associated fibroblasts: sources, regul… (Frontiers in Immunology)
• ANO6-mediated trogocytosis of cancer-associated fibroblasts… (Nature Cancer)
• Fibroblast–myeloid stromal crosstalk is associated with cli… (The Journal of Pathology)
• Complement in cancer-associated fibroblasts: sources, regul… (Frontiers in Immunology)
October 31, 2026 at 2:01 PM
Related papers from the past week:
• ANO6-mediated trogocytosis of cancer-associated fibroblasts… (Nature Cancer)
• Fibroblast–myeloid stromal crosstalk is associated with cli… (The Journal of Pathology)
• Complement in cancer-associated fibroblasts: sources, regul… (Frontiers in Immunology)
• ANO6-mediated trogocytosis of cancer-associated fibroblasts… (Nature Cancer)
• Fibroblast–myeloid stromal crosstalk is associated with cli… (The Journal of Pathology)
• Complement in cancer-associated fibroblasts: sources, regul… (Frontiers in Immunology)
📃Scientific paper: Fibroblast Heterogeneity Links Inflammatory Microenvironments to Tissue Remodeling in Chronic Rhinosinusitis
Year: 2026
➡️ Continued on ES/IODE
Year: 2026
➡️ Continued on ES/IODE
October 29, 2026 at 5:02 PM
📃Scientific paper: Fibroblast Heterogeneity Links Inflammatory Microenvironments to Tissue Remodeling in Chronic Rhinosinusitis
Year: 2026
➡️ Continued on ES/IODE
Year: 2026
➡️ Continued on ES/IODE
European Respiratory Journal: Pulmonary fibrosis is driven by chronic inflammation that links immune dysregulation to fibroblast activation, paving the way for targeted, personalised therapeutic strategies https://bit.ly/3S0FYcR
October 29, 2026 at 9:43 AM
European Respiratory Journal: Pulmonary fibrosis is driven by chronic inflammation that links immune dysregulation to fibroblast activation, paving the way for targeted, personalised therapeutic strategies https://bit.ly/3S0FYcR
CAR-macrophage immunotherapy targeting fibroblast-like synoviocytes ameliorates inflammatory and degenerative arthritis https://www.biorxiv.org/content/10.64898/2026.10.25.761728v1
October 28, 2026 at 10:47 AM
CAR-macrophage immunotherapy targeting fibroblast-like synoviocytes ameliorates inflammatory and degenerative arthritis https://www.biorxiv.org/content/10.64898/2026.10.25.761728v1
CAR-macrophage immunotherapy targeting fibroblast-like synoviocytes ameliorates inflammatory and degenerative arthritis https://www.biorxiv.org/content/10.64898/2026.10.25.761728v1
October 28, 2026 at 10:47 AM
CAR-macrophage immunotherapy targeting fibroblast-like synoviocytes ameliorates inflammatory and degenerative arthritis https://www.biorxiv.org/content/10.64898/2026.10.25.761728v1
A fibroblast walked into a bar.
The bartender said, "Smelly!"
The bartender said, "Smelly!"
October 27, 2026 at 3:20 PM
A fibroblast walked into a bar.
The bartender said, "Smelly!"
The bartender said, "Smelly!"
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice.
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
An Astrocytic Factor Slows Whole-Body Aging in Mice | Lifespan Research Institute
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice. A factor from a well-known family FGFs are signaling molecules that share structural and functional commonalities and play crucial roles in biology, including neural function [1]. Some of these molecules are secreted, and
lifespan.io
October 30, 2026 at 8:00 PM
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice.
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
🔬 Hidden world of “kissing bug” parasite, Trypanosoma cruzi, nesting within a human fibroblast cell is revealed in an image by LSHTM student Richard Atherton.
The image received an honourable mention in the Nikon Small World photomicrography competition.
Read more 👉 lnkd.in/p/eEHCMr_U
The image received an honourable mention in the Nikon Small World photomicrography competition.
Read more 👉 lnkd.in/p/eEHCMr_U
October 26, 2026 at 11:03 AM
🔬 Hidden world of “kissing bug” parasite, Trypanosoma cruzi, nesting within a human fibroblast cell is revealed in an image by LSHTM student Richard Atherton.
The image received an honourable mention in the Nikon Small World photomicrography competition.
Read more 👉 lnkd.in/p/eEHCMr_U
The image received an honourable mention in the Nikon Small World photomicrography competition.
Read more 👉 lnkd.in/p/eEHCMr_U
The Utility and Potential Pitfalls of Fibroblast Activation Protein-Alpha (FAP) Immunohistochemistry in Diagnosing Invasive Colorectal Adenocarcinoma in Biopsies www.ovid.com/10.1097/PAI....
The Utility and Potential Pitfalls of Fibroblast... : Applied Immunohistochemistry & Molecular Morphology
Diagnosing invasive colorectal adenocarcinoma (CRC) in limited biopsy samples can be challenging. This study evaluates fibroblast activation...
www.ovid.com
October 26, 2026 at 10:34 AM
The Utility and Potential Pitfalls of Fibroblast Activation Protein-Alpha (FAP) Immunohistochemistry in Diagnosing Invasive Colorectal Adenocarcinoma in Biopsies www.ovid.com/10.1097/PAI....
Spatial transcriptomic profiling reveals #fibroblast and inflammatory signatures in calcinosis of chronic cutaneous lupus
Bao et al
https://doi.org/10.1016/j.xjidi.2026.100504
#DermatologyJournal #Dermatology #derm #dermatologist #dermscience #dermatologyresearch #Spatialtranscriptomic
Bao et al
https://doi.org/10.1016/j.xjidi.2026.100504
#DermatologyJournal #Dermatology #derm #dermatologist #dermscience #dermatologyresearch #Spatialtranscriptomic
October 27, 2026 at 2:30 PM
Spatial transcriptomic profiling reveals #fibroblast and inflammatory signatures in calcinosis of chronic cutaneous lupus
Bao et al
https://doi.org/10.1016/j.xjidi.2026.100504
#DermatologyJournal #Dermatology #derm #dermatologist #dermscience #dermatologyresearch #Spatialtranscriptomic
Bao et al
https://doi.org/10.1016/j.xjidi.2026.100504
#DermatologyJournal #Dermatology #derm #dermatologist #dermscience #dermatologyresearch #Spatialtranscriptomic