Unraveling the molecular basis of sensory attributes in smoking spices: a nontargeted metabolite analysis using liquid chromatography high resolution mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Unraveling the molecular basis of sensory attributes in smoking spices: a nontargeted metabolite analysis using liquid chromatography high resolution mass spectrometry
Although natural spices are widely applied for their complex aromas and flavors, the molecular mechanisms that drive these sensory perceptions remain obscure...
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December 22, 2025 at 9:27 PM
Unraveling the molecular basis of sensory attributes in smoking spices: a nontargeted metabolite analysis using liquid chromatography high resolution mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Comparative serum metabolomic profiling of hypertension in different traditional Chinese medicine syndromes #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Comparative serum metabolomic profiling of hypertension in different traditional Chinese medicine syndromes
BackgroundHypertension is a crucial risk factor for cardiovascular diseases. Previous studies have revealed the serum metabolic profiles of patients with hyp...
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December 19, 2025 at 6:10 PM
Comparative serum metabolomic profiling of hypertension in different traditional Chinese medicine syndromes #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
UHPLC-MS/MS-based plasma untargeted lipidomic analysis in patients with diabetes mellitus combined with hyperuricemia #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | UHPLC-MS/MS-based plasma untargeted lipidomic analysis in patients with diabetes mellitus combined with hyperuricemia
ObjectiveTo compare the differences in lipid metabolites between patients with diabetes mellitus combined with hyperuricemia (DH) and diabetes mellitus (DM) ...
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December 1, 2025 at 6:50 PM
UHPLC-MS/MS-based plasma untargeted lipidomic analysis in patients with diabetes mellitus combined with hyperuricemia #FrontMolBiosci www.frontiersin.org/journals/mol...
An exploratory study of urinary proteome in trigeminal neuralgia #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | An exploratory study of urinary proteome in trigeminal neuralgia
BackgroundTrigeminal neuralgia (TN) is a neurological disorder characterized by severe pain and a complex pathogenesis. This condition seriously affects pati...
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November 18, 2025 at 7:34 PM
An exploratory study of urinary proteome in trigeminal neuralgia #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Global DNA-methylation in quantitative epigenetics: orbitrap mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Global DNA-methylation in quantitative epigenetics: orbitrap mass spectrometry
DNA methylation is the most common epigenetic modification in both prokaryotic and eukaryotic genomes. Here we present a method based on highly efficient aci...
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October 13, 2025 at 6:28 PM
Global DNA-methylation in quantitative epigenetics: orbitrap mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Toxicological analysis of metabolites in ischemic stroke based on salivary metabolomics #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Toxicological analysis of metabolites in ischemic stroke based on salivary metabolomics
ObjectiveTo elucidate the characteristic patterns of salivary metabolic network instability in IS patients, reveal the association mechanism between amino ac...
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September 15, 2025 at 6:35 PM
Toxicological analysis of metabolites in ischemic stroke based on salivary metabolomics #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
LC-HRMS fingerprinting and chemometrics for the characterization and classification of Lotus cultivars from Uruguay: a study on phenolic composition #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | LC-HRMS fingerprinting and chemometrics for the characterization and classification of Lotus cultivars from Uruguay: a study on phenolic composition
IntroductionThe Lotus genus, part of the legume family, comprises over 180 species distributed across diverse ecosystems worldwide. Its broad genetic diversi...
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September 15, 2025 at 6:34 PM
LC-HRMS fingerprinting and chemometrics for the characterization and classification of Lotus cultivars from Uruguay: a study on phenolic composition #FrontMolBiosci www.frontiersin.org/journals/mol...
Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures
BackgroundSudden sensorineural hearing loss (SSNHL) is a common otological disorder with complex etiologies and unclear pathophysiology. This study aimed to ...
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July 30, 2025 at 5:41 AM
Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Functional metabolomics: unlocking the role of small molecular metabolites #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Functional metabolomics: unlocking the role of small molecular metabolites
Metabolomics is an expanding field dedicated to elucidating metabolic disorders by analyzing endogenous small molecules in biological samples. With the rapid...
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July 25, 2025 at 3:38 AM
Functional metabolomics: unlocking the role of small molecular metabolites #FrontMolBiosci www.frontiersin.org/journals/mol...
Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry
IntroductionTaohong Siwu Decoction (THSW Decoction), a classic formula for treating blood stasis, has demonstrated significant clinical efficacy in the treat...
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July 15, 2025 at 1:14 PM
Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry
BackgroundEpilepsy affects approximately 70 million individuals globally, posing significant neurobiological and psychological challenges. Despite the availa...
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July 2, 2025 at 1:31 PM
Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry
Teratozoospermia, a qualitative sperm disorder characterized by abnormal sperm morphology, represents one of the causes of male infertility worldwide. The me...
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July 2, 2025 at 1:30 PM
Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Clinical metabolomics reveals potential diagnostic biomarkers in serum samples from patients with generalized ligamentous laxity #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Clinical metabolomics reveals potential diagnostic biomarkers in serum samples from patients with generalized ligamentous laxity
ObjectivesDiscovering the potential metabolic alterations underlying generalized ligamentous laxity (GLL) is crucial for identifying new therapeutic targets ...
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June 17, 2025 at 8:55 PM
Clinical metabolomics reveals potential diagnostic biomarkers in serum samples from patients with generalized ligamentous laxity #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics
IntroductionKawasaki disease (KD) is an acute systemic vasculitis that primarily affects coronary arteries, and delayed diagnosis increases the risk of cardi...
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May 27, 2025 at 8:11 PM
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study
Athletes use hypoxic training methods to enhance their performance under altitude conditions. Comparative studies involving populations from low (500–2,000 m...
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May 26, 2025 at 7:09 PM
Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Cuscutae Semen in depression-induced ovarian dysfunction: metabolomics with UPLC-QToF-MS in female mice #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Cuscutae Semen in depression-induced ovarian dysfunction: metabolomics with UPLC-QToF-MS in female mice
The increasing prevalence of depression profoundly affects female ovarian health. Although Cuscutae Semen (CS) is acknowledged for treating reproductive diso...
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May 15, 2025 at 6:16 PM
Cuscutae Semen in depression-induced ovarian dysfunction: metabolomics with UPLC-QToF-MS in female mice #FrontMolBiosci www.frontiersin.org/journals/mol...
Metabolomic analysis of fatal hypothermia using ultra-high-performance liquid chromatography‒mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Metabolomic analysis of fatal hypothermia using ultra-high-performance liquid chromatography‒mass spectrometry
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May 1, 2025 at 12:52 PM
Metabolomic analysis of fatal hypothermia using ultra-high-performance liquid chromatography‒mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
High-throughput metabolomics exploring the pharmacological effects and mechanism of icariin on rheumatoid arthritis rat based on ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | High-throughput metabolomics exploring the pharmacological effects and mechanism of icariin on rheumatoid arthritis rat based on ultrahigh-performance liquid chromatography coupled with qu...
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April 24, 2025 at 6:53 PM
High-throughput metabolomics exploring the pharmacological effects and mechanism of icariin on rheumatoid arthritis rat based on ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Identification of metabolomics-based biomarker discovery in individuals with down syndrome utilizing kernel-tree model-enhanced explainable artificial intelligence methodology #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Identification of metabolomics-based biomarker discovery in individuals with down syndrome utilizing kernel-tree model-enhanced explainable artificial intelligence methodology
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April 24, 2025 at 6:52 PM
Identification of metabolomics-based biomarker discovery in individuals with down syndrome utilizing kernel-tree model-enhanced explainable artificial intelligence methodology #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome
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April 24, 2025 at 6:51 PM
Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome #FrontMolBiosci www.frontiersin.org/journals/mol...
Urinary marker of oxidative stress in children correlates with molecules in exhaled breath #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Urinary marker of oxidative stress in children correlates with molecules in exhaled breath
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April 10, 2025 at 10:54 AM
Urinary marker of oxidative stress in children correlates with molecules in exhaled breath #FrontMolBiosci www.frontiersin.org/journals/mol...
Mass spectrometry-based metabolomics reveal the effects and potential mechanism of isochlorogenic acid A in MC3T3-E1 cells #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Mass spectrometry-based metabolomics reveal the effects and potential mechanism of isochlorogenic acid A in MC3T3-E1 cells
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April 9, 2025 at 6:03 PM
Mass spectrometry-based metabolomics reveal the effects and potential mechanism of isochlorogenic acid A in MC3T3-E1 cells #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Serum metabolic profiling of patients with diabetic kidney disease based on gas chromatography-mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Serum metabolic profiling of patients with diabetic kidney disease based on gas chromatography-mass spectrometry
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April 1, 2025 at 8:12 PM
Serum metabolic profiling of patients with diabetic kidney disease based on gas chromatography-mass spectrometry #FrontMolBiosci www.frontiersin.org/journals/mol...
Metabolite profiling, antimalarial potentials of Schleichera oleosa using LC-MS and GC-MS: in vitro, molecular docking and molecular dynamics #FrontMolBiosci www.frontiersin.org/journals/mol...
Frontiers | Metabolite profiling, antimalarial potentials of Schleichera oleosa using LC-MS and GC-MS: in vitro, molecular docking and molecular dynamics
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March 4, 2025 at 1:00 PM
Metabolite profiling, antimalarial potentials of Schleichera oleosa using LC-MS and GC-MS: in vitro, molecular docking and molecular dynamics #FrontMolBiosci www.frontiersin.org/journals/mol...
Plasma proteome fingerprint in kidney diseases #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...
Frontiers | Plasma proteome fingerprint in kidney diseases
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February 3, 2025 at 6:48 PM
Plasma proteome fingerprint in kidney diseases #FrontMolBiosci #MassSpec www.frontiersin.org/journals/mol...