#GDChBiochem2024
Congratulations to Nina Hartrampf on winning the German Chemical Biology Lectureship and giving an amazing lecture at #GDChBioChem2024 of @gdchbiochem.bsky.social. She gave an overview, how her lab pushes the boundaries of chemical synthesis of (modified) peptides. pubs.rsc.org/en/content/a...
October 1, 2024 at 3:02 PM
Interesting talk by Kerstin Goepfrich at #GDChBioChem2024 #Biochemistry2024. She talked about synthetic biology with RNA origami to engineer and evolve minimalistic synthetic cells. www.biorxiv.org/content/10.1...
October 2, 2024 at 8:33 AM
Great talk by Herbert Waldmann at the @gdchbiochem.bsky.social Conference #GDChBioChem2024. He talked about his group's exciting work on pseudo-natural products as well as their application to understand biology and discover e.g. targeted protein degraders. doi.org/10.1101/2024...
September 30, 2024 at 11:49 AM
Amazing to listen to an update about the great work of the group of Seino Jongkees at #GDChBioChem2024 of @gdchbiochem.bsky.social. He talked about the power of mRNA display to identify potent and selective macrocyclic peptide ligands for target proteins. www.pnas.org/doi/abs/10.1...
October 2, 2024 at 8:18 AM
It was great to chair the first morning session of #GDChBioChem2024 by @gdchbiochem.bsky.social with amazing talks by Andrea Rentmeister, Mahesh Vibhute from the Hannes Mutschler Lab and Clemens Richert covering diverse aspects of DNA and RNA (bio)-chemistry as well as ribosome-free translation.
October 1, 2024 at 8:59 AM
Interesting talk by Mahesh Vibhute from the Hannes Mutschler Lab at #GDChBioChem2024 #Biochemistry2024. He talked about his work on producing a fluorogenic DNA Aptamer that can be used in cells. www.biorxiv.org/content/10.1...
October 1, 2024 at 7:48 AM
Great talk by Tamir Gonen at #GDChBioChem2024 of @gdchbiochem.bsky.social. He talked about his group's groundbreaking work on microED. Very interesting insights into its applications in drug discovery and structure determination for small membrane proteins. www.sciencedirect.com/science/arti...
October 1, 2024 at 2:01 PM
Amazing lecture by Ronald Micura at #GDChBioChem2024 by @gdchbiochem.bsky.social. He talked about small molecules that covalently modify specific RNA using alkyl halides as warhead. On the way to covalent drug discovery for RNAs? Look out for the exciting publication coming out soon.
October 1, 2024 at 9:30 AM
We had a great #GDChBiochem2024 conference and would like to share a few more impressions of our award winners. Congratulations again to Andreas Marx (Albrecht-Kossel-Preis), Nina Hartrampf (German Chemical Biology Lectureship) as well as Davide Tamborrini and Minh Nguyen Trung (Förderpreis).
October 9, 2024 at 8:20 AM
We are looking forward to the final day of #GDChBioChem2024 #Biochemistry2024. Today, we will have a great program of lectures and learn, who will take home the prizes for the best posters.
October 2, 2024 at 6:40 AM
Great talk by Dorothea Fiedler at #GDChBiochem2024. She talked about the development of advanced proteomic methods to study the posttranslational modification of protein pyrophosphorylation. www.nature.com/articles/s41...
September 30, 2024 at 12:31 PM
An interesting award lecture also by the second winner of the Förderpreis of @gdchbiochem.bsky.social, Minh Nguyen Trung, at #GDChBioChem2024. He talked about his research in the Dorothea Fiedler lab on the metabolism of inositol phosphates.
pubs.acs.org/doi/10.1021/...
October 1, 2024 at 3:41 PM
Great talk by Seino Jongkees at #GDChBioChem2024 #Biochemistry2024. He talked about the development of technologies to combine mRNA display with chemical modifications in order to study the interactions of macrocyclic glycopeptides. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
October 2, 2024 at 8:11 AM
Great lecture by Ralf Jungmann at #GDChBioChem2024 of @gdchbiochem.bsky.social. He talked about his group's amazing research on super-resolution microscopy using resolution enhancement by sequential imaging (RESI) allowing Ångström-resolution fluorescence microscopy www.nature.com/articles/s41...
Ångström-resolution fluorescence microscopy - Nature
The authors introduce a single-molecule DNA-barcoding method, resolution enhancement by sequential imaging, that improves the resolution of fluorescence microscopy down to the Ångström scale using off...
www.nature.com
October 1, 2024 at 12:34 PM
We are looking forward to the second day of #GDChBioChem2024 #Biochemistry2024. Today we will have an exciting program of lectures, talks by the winners of the Kossel Prize, Andreas Marx, and of the Förderpreise of @gdchbiochem.bsky.social as well as a poster session.
October 1, 2024 at 6:13 AM
#GDChBioChem2024 by @gdchbiochem.bsky.social of @gdch.bsky.social was an amazing event with a lot of exciting science. I want to thank the organizers, Stefan Raunser, Albert Sickmann and Daniel Summerer, very much for making this such a great experience.
October 2, 2024 at 12:08 PM
Exciting talk by Michael Jewett at #GDChBioChem2024 of @gdchbiochem.bsky.social. He talked about the application and engineering of cell-free systems to sustainably produce bioproducts. Great insights into AI-assisted protein engineering and into designing ribosomes www.biorxiv.org/content/10.1...
October 2, 2024 at 7:50 AM
The final talk of #GDChBioChem2024 was given by Luise Franz from the Christian Hackenberger lab. She talked about the use of cell penetrating peptides to deliver nanobodies into cells. Interesting insights into restoring CFTR F508del function. www.biorxiv.org/content/10.1...
October 2, 2024 at 10:27 AM
Great talk by Sabine Schneider at #GDChBioChem2024 #Biochemistry2024. She talked about biochemical tools to better understand RNA modifications on the main example of the demethylase AlkBH1 that works on m3C, m5C and m1A in mitochondrial tRNA. journals.biologists.com/jcs/article/...
October 1, 2024 at 10:28 AM
Getting ready for the final day of #GDChBioChem2024 of @gdchbiochem.bsky.social. Especially looking forward to talks by John Yates, Kerstin Göpfrich, Michael Jewett, Seino Jongkees and Luise Franz from the Christian Hackenberger lab as well as the ceremony for the poster awards.
October 2, 2024 at 6:49 AM
Getting ready for day 2 of #GDChBioChem2024 of @gdchbiochem.bsky.social. Today I am especially excited for talks by Andrea Rentmeister, Ronald Micura, Sabine Schneider and Kossel Prize winner Andreas Marx as well as the poster session and the general assembly of @GDCh_BioChem.
October 1, 2024 at 6:01 AM
Inspiring talk by Andrea Rentmeister at #GDChBioChem2024 by @gdchbiochem.bsky.social. She talked about her group's amazing work on specifically modifying mRNAs using SAM analogs as well as on light-controlled mRNAs via FlashCaps. www.nature.com/articles/s41...
Photocaged 5′ cap analogues for optical control of mRNA translation in cells - Nature Chemistry
Analogues of mRNA 5′ caps containing a photo-cleavable group have now been developed. These so-called FlashCaps can be used for routine in vitro transcription to make long mRNAs containing a cap. In c...
www.nature.com
October 1, 2024 at 7:28 AM

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#ListenToBlackVoices
October 2, 2024 at 8:20 AM
Exciting talk by Stephan Sieber at #GDChBioChem2024. He talked about his group's research into finding modalities to kill bacteria in new ways. Great insights into strategies involving enzyme overactivation and induction of cellular stress. www.nature.com/articles/s41...
September 30, 2024 at 3:07 PM
#GDChBioChem2024 comes to an end with closing words by Stefan Raunser. We thanks the organizers, Stefan Raunser, Albert Sickmann and Daniel Summerer very much for organizing such a great event. We are hoping to see many of you again at #GDChBioChem2026.
October 2, 2024 at 12:03 PM