#GuessThatISH
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zebrafishrock.bsky.social
Let’s mix it up for #GuessThatISH this week! We assume that everyone knows what the “ISH” in GuessThatISH stands for. 💪 But for those that need a little help, please share what you think it is… One small twist: WRONG ANSWERS ONLY! Let’s get creative 🤪 Winner gets bragging rights! #ThisseThursday 🧪
Side view of a zebrafish embryo that has been stained with an in situ hybridization probe for titin
April 3, 2025 at 5:33 PM
zebrafishrock.bsky.social
We are moving slower than a sea slug in the latest edition of #GuessThatISH 🫩 Take a guess! We double-dare you 🤭
zebrafishrock.bsky.social Zebrafish Rock! @zebrafishrock.bsky.social · Jun 5
We've made it to another #ThisseThursday and that means it's time for #GuessThatISH! 😌 How would you describe the in situ staining (purple) in this #zebrafish embryo? WRONG ANSWERS PLEASE!!! The person with the most likes gets bragging rights and will be the envy of their peers 😏 Happy guessing! 🧪
Dorsal view of an early stage zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe.
June 5, 2025 at 7:19 PM
zebrafishrock.bsky.social
Free swag on the line in this special anniversary-edition of #GuessThatISH! 🧪
zebrafishrock.bsky.social Zebrafish Rock! @zebrafishrock.bsky.social · Feb 13
It's been FOUR years since the first #GuessThatISH post on social media 🍻 We can't think of a better way to celebrate than to play another game! How would you describe the staining in this #zebrafish larva? WRONG ANSWERS ONLY! The person w/ most ❤️ gets a free fishy mug ☕ LET'S GO! #ThisseThursday 🧪
Dorsal view of a zebrafish larva that has been stained (in dark purple) with an unknown in situ hybridization probe. Credit to Thisse and Thisse et al.
February 13, 2025 at 5:52 PM
zebrafishrock.bsky.social
As seen on Twitter, #GuessThatISH makes its debut on Bluesky 🤩 Get your thinking caps on because this first one is a fin-flapper 💪 How would you describe the expression in this #zebrafish embryo? WRONG ANSWERS ONLY! The person w/ the most likes gets bragging rights. Happy guessing! #ThisseThursday 🧪
Dorsal view of a zebrafish embryo that has been stained (In purple) with an unknown in situ hybridization probe. Credit to Thisse and Thisse et al.
November 14, 2024 at 1:36 PM
zebrafishrock.bsky.social
We nearly forgot!!! Time to get creative and play #GuessThatISH 🤪 🧪 How would you describe the staining (in purple) in this #zebrafish embryo? WRONG ANSWERS ONLY! The person with the most likes by the weekend gets bragging rights and a small heaping of brine shrimp 🦐 Happy guessing! #ThisseThursday
Side view of an early stage zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe.
January 30, 2025 at 6:50 PM
zebrafishrock.bsky.social
We’re calling this one ⌛️ Bragging rights go to first time winner(?) @chrmosimann.bsky.social for ‘George Castanza from Seinfeld’. For those staunch #GuessThatISH followers, the gene was bmp6, which marks the mesendoderm at this stage of development. Look out for the next game in two weeks! #RockOn
zebrafishrock.bsky.social Zebrafish Rock! @zebrafishrock.bsky.social · Mar 20
This week has flown by! Let's slow it down & play our favorite guessing game 😜 How would you describe the expression in this #zebrafish embryo? You know the drill: WRONG ANSWERS ONLY! The person w/ most likes gets bragging rights and a line of distinction on their CV! #GuessThatISH #ThisseThursday 🧪
Side view of an early stage zebrafish embryo that has been stained (in purple) with an unknown in situ hybridisation probe.
March 22, 2025 at 1:45 PM
zebrafishrock.bsky.social
We have a tie! The community couldn’t decide what the right side of a horse’s face was so @burgesslab.bsky.social 🙂 & @mads100tist.bsky.social 🙃 take bragging rights! For those unsettled by this news, the gene was asph, which marks several developmental structures (image below). Thanks for playing!
Screen capture of entries for GuessThatISH of a horse Dorsal view of a zebrafish embryo for asph in situ hybridization probe
December 7, 2024 at 4:49 PM
zebrafishrock.bsky.social
It's been FOUR years since the first #GuessThatISH post on social media 🍻 We can't think of a better way to celebrate than to play another game! How would you describe the staining in this #zebrafish larva? WRONG ANSWERS ONLY! The person w/ most ❤️ gets a free fishy mug ☕ LET'S GO! #ThisseThursday 🧪
Dorsal view of a zebrafish larva that has been stained (in dark purple) with an unknown in situ hybridization probe. Credit to Thisse and Thisse et al.
February 13, 2025 at 9:43 AM
zebrafishrock.bsky.social
It's yet another #ThisseThursday so let's take a break and play #GuessThatISH! 🤪 How would you describe the expression (in purple) in this #zebrafish embryo? WRONG ANSWERS ONLY!!! The person with the most likes gets to brag about it to their colleagues and can add it to their CV 💪 Happy guessing! 🧪
Dorsal view of a 48 hours post fertilization zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe.
April 17, 2025 at 8:45 AM
zebrafishrock.bsky.social
We've been struggling with #GuessThatISH but we will not be deterred! Let's play our favorite guessing game 😜 How would you describe the staining (in purple) in this #zebrafish embryo? WRONG ANSWERS ONLY! Bragging rights go to the winner so don't forget to vote 🙏 Happy guessing! #ThisseThursday 🧪
Dorsal view of a zebrafish embryo that has been stained with an unknown in situ hybridization probe (in purple).
May 8, 2025 at 1:28 PM
zebrafishrock.bsky.social
Your favorite day of the week has arrived! Time to play #GuessThatISH 😜 How would you describe the expression in this early #zebrafish embryo? WRONG ANSWERS ONLY! The person with the most likes secures bragging rights for the week and can write a line on their CV 🤩 Happy guessing! #ThisseThursday 🧪
Image of an early somite-stage zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe.
January 16, 2025 at 10:31 AM
zebrafishrock.bsky.social
This week has flown by! Let's slow it down & play our favorite guessing game 😜 How would you describe the expression in this #zebrafish embryo? You know the drill: WRONG ANSWERS ONLY! The person w/ most likes gets bragging rights and a line of distinction on their CV! #GuessThatISH #ThisseThursday 🧪
Side view of an early stage zebrafish embryo that has been stained (in purple) with an unknown in situ hybridisation probe.
March 20, 2025 at 1:44 PM
zebrafishrock.bsky.social
ENCORE! We've heard the rave reviews from the first #GuessThatISH so we are back for more 😜 How would you describe the staining in this #zebrafish embryo? WRONG ANSWERS ONLY! The person with the most likes gets bragging rights and a line of distinction on their CV 😏 Happy guessing! #ThisseThursday 🧪
Dorsal view of a zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe.
December 5, 2024 at 1:19 PM
kevinthiessen.bsky.social
Definitely saving this in situ for #GuessThatISH
December 5, 2025 at 8:14 PM
zebrafishrock.bsky.social
We're testing the waters to see if #GuessThatISH should return to Bluesky 🤔 Here's how you play: We show you an image of a #zebrafish embryo/larva that has been labeled w/ a chromogenic in situ hybridization probe & you tell us what it looks like 😎 The twist?! WRONG ANSWERS ONLY! 🤪 #ThisseThursday 🧪
Side view of a zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe. Credit to Thisse & Thisse et al.
June 4, 2026 at 12:27 PM
zebrafishrock.bsky.social
We've made it to another #ThisseThursday and that means it's time for #GuessThatISH! 😌 How would you describe the in situ staining (purple) in this #zebrafish embryo? WRONG ANSWERS PLEASE!!! The person with the most likes gets bragging rights and will be the envy of their peers 😏 Happy guessing! 🧪
Dorsal view of an early stage zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe.
June 5, 2025 at 1:04 PM
zebrafishrock.bsky.social
Your favorite guessing game has returned to social media! Here's how to play #GuessThatISH:

We present a pic of a #zebrafish embryo that has been stained using an unknown in situ probe by Thisse et al.

You tell us what it looks like! The catch? WRONG ANSWERS ONLY!

Let's play! #ThisseThursday 🧪
Top view of an early stage zebrafish embryo that has been stained with an unknown in situ hybridization probe. Head to the left. Big opaque yolk to the right. Credit to Thisse & Thisse et al.
November 6, 2025 at 2:22 PM
zebrafishrock.bsky.social
Your favorite day of the week has arrived! Let's play #GuessThatISH 🤪 How would you describe the expression (in purple) of this #zebrafish larva? You know the drill: WRONG ANSWERS ONLY! The person with the most likes gets a free zebrafish sticker from Redbubble 🤩 Happy guessing! #ThisseThursday 🧪
Dorsal view of a zebrafish larval that has been stained (in purple) with an unknown in situ hybridization probe. Parts of the brain are labelled, which looks suspiciously like something else.
December 4, 2025 at 12:29 PM
zebrafishrock.bsky.social
Thursday has arrived! It's time for everyone's favorite game, #GuessThatISH! What does the gene expression (in purple) look like in this #zebrafish embryo? WRONG ANSWERS ONLY!!! The person with the most likes gets bragging rights for the month. Happy guessing! #ThisseThursday
Image of an early stage zebrafish embryo that has been stained (in purple) with an unknown in situ hybridization probe. Credit to Thisse & Thisse.
September 21, 2023 at 10:59 AM
zebrafishrock.bsky.social
It's down to two!! Does this staining look like "the lungs" 🫁 or maybe "twins"👶👶 Or will "Millennium Falcon" 🚀 make a comeback?! You decide ❤️ Time to vote with your likes!
#RockTheVote #GuessThatISH
zebrafishrock.bsky.social Zebrafish Rock! @zebrafishrock.bsky.social · Nov 14
As seen on Twitter, #GuessThatISH makes its debut on Bluesky 🤩 Get your thinking caps on because this first one is a fin-flapper 💪 How would you describe the expression in this #zebrafish embryo? WRONG ANSWERS ONLY! The person w/ the most likes gets bragging rights. Happy guessing! #ThisseThursday 🧪
Dorsal view of a zebrafish embryo that has been stained (In purple) with an unknown in situ hybridization probe. Credit to Thisse and Thisse et al.
November 15, 2024 at 12:54 PM
zebrafishrock.bsky.social
#GuessThatISH returns for 2026! This full nonsense game is sure to get you smiling 😜 Can you guess what this unknown ISH probe stains (in purple) on this #zebrafish embryo? WRONG ANSWERS ONLY! Bragging rights for the winner 😎 Bonus points if you can guess the gene. Happy guessing! #ThisseThursday 🧪
Side view of the front half of a zebrafish embryo that has been stained with an unknown in situ hybridization probe (in purple). You can see the yolk (dark tan) and the outline of the eye (slightly dark beige) in addition to the purple spot on the head. Credit staining to Thisse and Thisse et al. Image taken from ZFIN.
January 15, 2026 at 10:07 AM
zebrafishrock.bsky.social
It's your favorite day of the week!!! Let's play #GuessThatISH! How would you describe this #zebrafish larva, which has been stained with an unknown in situ probe? WRONG ANSWERS PLEASE 😜 The person(s) with the most likes gets bragging rights for the week 😏 Happy guessing! #ThisseThursday
Side view of a zebrafish larva (in purple) that has been stained with an unknown in situ hybridization probe.
August 10, 2023 at 2:24 PM
zebrafishrock.bsky.social
Encore! Encore! After a successful relaunch, we are back for more #GuessThatISH! How would you describe the in situ expression (in purple) in this zebrafish embryo? WRONG ANSWERS ONLY! The person w/ the most likes gets bragging rights and a virtual pat on the back 😎 Happy guessing! #ThisseThursday 🧪
Dorsal view of a zebrafish embryo that has been stained with an unknown in situ hybridization probe (in purple). There is some stuff labeled near the eyes that looks suspicious! Credit to Thisse and Thisse et al.
November 20, 2025 at 12:04 PM
zebrafishrock.bsky.social
The year has been building towards this moment! It's time for the final #GuessThatISH of 2023 🥂 How would you describe the expression (in purple) in this zebrafish embryo? WRONG ANSWERS ONLY 😜 The person w/ the most likes on Bluesky gets a special commendation and a line on their CV! #ThisseThursday
Frontal view of a two days post fertilization zebrafish embryo. It has been stained with an unknown in situ hybridization probe.
December 14, 2023 at 3:38 PM
zebrafishrock.bsky.social
The wait is over! Time for another #GuessThatISH! Can you guess what the mysterious structure is in this zebrafish embryo? WRONG ANSWERS ONLY, PLEASE! The person with the best guess (according to our panel of judges) will bragging rights and an invite code to share! Happy guessing! #ThisseThursday
Dorsal view of a zebrafish embryo that has several structures stained with an unknown in situ hybridization probe. There is an arrow pointing to one of the structures.
October 5, 2023 at 12:31 PM