To evaluate the impact of the influenza virus (HPAIV) in the Peregrine Falcon, Integrated Population Modelling was used. The analyses revealed drastic declines in adult survival, suggesting a shift in HPAIV dynamics compared to the previous epizootics. Read more: doi.org/10.1111/1365...
February 4, 2026 at 10:07 AM
To evaluate the impact of the influenza virus (HPAIV) in the Peregrine Falcon, Integrated Population Modelling was used. The analyses revealed drastic declines in adult survival, suggesting a shift in HPAIV dynamics compared to the previous epizootics. Read more: doi.org/10.1111/1365...
First confirmed cases of High Pathogenicity Avian Influenza Virus (HPAIV) on Gough Island represent one of the most geographically isolated detections of HPAIV to date. But how did it get there?
Read on for a summary
Full paper: doi.org/10.1080/2222...
🧪🪶🌍
#seabirds
Read on for a summary
Full paper: doi.org/10.1080/2222...
🧪🪶🌍
#seabirds
February 26, 2026 at 12:18 PM
First confirmed cases of High Pathogenicity Avian Influenza Virus (HPAIV) on Gough Island represent one of the most geographically isolated detections of HPAIV to date. But how did it get there?
Read on for a summary
Full paper: doi.org/10.1080/2222...
🧪🪶🌍
#seabirds
Read on for a summary
Full paper: doi.org/10.1080/2222...
🧪🪶🌍
#seabirds
BTW — Did you know …
"Scientists have discovered evidence that Northern Gannets can recover from bird flu and that unusual black iris coloration is linked to a previous HPAIV infection"
🧪
www.rspb.org.uk/media-centre...
"Scientists have discovered evidence that Northern Gannets can recover from bird flu and that unusual black iris coloration is linked to a previous HPAIV infection"
🧪
www.rspb.org.uk/media-centre...
Black eyes in seabirds indicates bird flu survival
Scientists have discovered evidence that Northern Gannets can recover from bird flu and that unusual black iris coloration is linked to a previous HPAIV infection
www.rspb.org.uk
December 14, 2025 at 2:47 AM
BTW — Did you know …
"Scientists have discovered evidence that Northern Gannets can recover from bird flu and that unusual black iris coloration is linked to a previous HPAIV infection"
🧪
www.rspb.org.uk/media-centre...
"Scientists have discovered evidence that Northern Gannets can recover from bird flu and that unusual black iris coloration is linked to a previous HPAIV infection"
🧪
www.rspb.org.uk/media-centre...
EARLY VIEW in IBIS
Effect of a previous high pathogenicity avian influenza (HPAIV) infection on the breeding success of Northern Gannets (Morus bassanus) | onlinelibrary.wiley....
Sue Lewis et al | #ornithology 🪶
Effect of a previous high pathogenicity avian influenza (HPAIV) infection on the breeding success of Northern Gannets (Morus bassanus) | onlinelibrary.wiley....
Sue Lewis et al | #ornithology 🪶
September 25, 2025 at 1:54 PM
EARLY VIEW in IBIS
Effect of a previous high pathogenicity avian influenza (HPAIV) infection on the breeding success of Northern Gannets (Morus bassanus) | onlinelibrary.wiley....
Sue Lewis et al | #ornithology 🪶
Effect of a previous high pathogenicity avian influenza (HPAIV) infection on the breeding success of Northern Gannets (Morus bassanus) | onlinelibrary.wiley....
Sue Lewis et al | #ornithology 🪶
Avian flu in Alaskan polar bears
In other news, a report this week in Science Direct notes that three dead polar bears in Alaska were infected with highly pathogenic H5 avian influenza (HPAIV) clade 2.3.4.4b viruses in 2023 and 2024.
In other news, a report this week in Science Direct notes that three dead polar bears in Alaska were infected with highly pathogenic H5 avian influenza (HPAIV) clade 2.3.4.4b viruses in 2023 and 2024.
September 25, 2026 at 1:09 AM
Avian flu in Alaskan polar bears
In other news, a report this week in Science Direct notes that three dead polar bears in Alaska were infected with highly pathogenic H5 avian influenza (HPAIV) clade 2.3.4.4b viruses in 2023 and 2024.
In other news, a report this week in Science Direct notes that three dead polar bears in Alaska were infected with highly pathogenic H5 avian influenza (HPAIV) clade 2.3.4.4b viruses in 2023 and 2024.
This is type of cool and quiet science that excites me. In 2023, #H5N1 hit California condors hard: >21 birds dead. Just ~560 remain globally. Researchers asked: could a poultry vaccine help? They ran a trial that might change wildlife conservation & save the species.🧪
wwwnc.cdc.gov/eid/article/...
wwwnc.cdc.gov/eid/article/...
Safety and Immunogenicity of Poultry Vaccine for Protecting Critically Endangered Avian Species against Highly Pathogenic Avian Influenza Virus, United States
Vaccine for Protecting Avian Species against HPAIV
wwwnc.cdc.gov
April 18, 2025 at 5:09 PM
This is type of cool and quiet science that excites me. In 2023, #H5N1 hit California condors hard: >21 birds dead. Just ~560 remain globally. Researchers asked: could a poultry vaccine help? They ran a trial that might change wildlife conservation & save the species.🧪
wwwnc.cdc.gov/eid/article/...
wwwnc.cdc.gov/eid/article/...
H5N2 HPAIV from a peregrine falcon on Amami-Oshima Island, Japan - reassortant between H5N8 and LPAI. PA protein contained uncommon residues, S224P and N383D, associated with enhanced pathogenicity
👉 www.sciencedirect.com/science/arti...
👉 www.sciencedirect.com/science/arti...
January 27, 2026 at 12:11 AM
H5N2 HPAIV from a peregrine falcon on Amami-Oshima Island, Japan - reassortant between H5N8 and LPAI. PA protein contained uncommon residues, S224P and N383D, associated with enhanced pathogenicity
👉 www.sciencedirect.com/science/arti...
👉 www.sciencedirect.com/science/arti...
mechanistic model for understanding spatiotemporal transmission of HPAI in Denmark = decision-making tool. removing 50% of carcasses reduced the annual HPAIV mortality by 38% - more evidence for carcass removal.
👉 www.sciencedirect.com/science/arti...
👉 www.sciencedirect.com/science/arti...
January 19, 2025 at 10:50 PM
mechanistic model for understanding spatiotemporal transmission of HPAI in Denmark = decision-making tool. removing 50% of carcasses reduced the annual HPAIV mortality by 38% - more evidence for carcass removal.
👉 www.sciencedirect.com/science/arti...
👉 www.sciencedirect.com/science/arti...
“These data indicate that HPAIV infection may represent an emerging threat to polar bear health within the Alaska Arctic; though, population immunity seems to be building and may protect this species from widespread demographic impacts of disease,” the authors said.
September 25, 2026 at 1:11 AM
“These data indicate that HPAIV infection may represent an emerging threat to polar bear health within the Alaska Arctic; though, population immunity seems to be building and may protect this species from widespread demographic impacts of disease,” the authors said.
14% of Texas dairy #farmworkers tested had elevated levels of neutralizing antibodies against a recombinant Influenza A(H5N1) virus of clade 2.3.4.4b
#H5N1
discovermednews.com/texas-dairy-...
#H5N1
discovermednews.com/texas-dairy-...
Farmworkers exposed to HPAIV H5N1
To ascertain whether the farmworkers have been exposed to HPAIV H5N1, the authors measured neutralizing antibodies against recombinant H5N1.
discovermednews.com
November 30, 2024 at 4:57 PM
14% of Texas dairy #farmworkers tested had elevated levels of neutralizing antibodies against a recombinant Influenza A(H5N1) virus of clade 2.3.4.4b
#H5N1
discovermednews.com/texas-dairy-...
#H5N1
discovermednews.com/texas-dairy-...
in vitro experiments demonstrate that (MEK1/2 inhibitor) zapnometinib significantly impairs viral replication across multiple HPAIV strains, including H5N1 clade 2.3.4.4b in cell lines and primary bronchial epithelial cells.
👉 www.tandfonline.com/doi/full/10....
👉 www.tandfonline.com/doi/full/10....
February 24, 2025 at 5:31 AM
in vitro experiments demonstrate that (MEK1/2 inhibitor) zapnometinib significantly impairs viral replication across multiple HPAIV strains, including H5N1 clade 2.3.4.4b in cell lines and primary bronchial epithelial cells.
👉 www.tandfonline.com/doi/full/10....
👉 www.tandfonline.com/doi/full/10....
The detection of HPAIV on Gough Island is a stark reminder of the vulnerability of remote ecosystems to infectious diseases, and for the need to alleviate already persisting pressures on globally important seabird populations.
February 26, 2026 at 12:18 PM
The detection of HPAIV on Gough Island is a stark reminder of the vulnerability of remote ecosystems to infectious diseases, and for the need to alleviate already persisting pressures on globally important seabird populations.
The report documents the discovery, the first finding of HPAIV in a cetacean in North America, from the initial response by UF's Marine Animal Rescue team to a report of a distressed dolphin in Dixie County, Florida.
phys.org/news/2024-04...
phys.org/news/2024-04...
Florida dolphin found with highly pathogenic avian flu: Report
The case of a Florida bottlenose dolphin found with highly pathogenic avian influenza virus, or HPAIV—a discovery made by University of Florida researchers in collaboration with multiple other a...
phys.org
April 26, 2024 at 7:43 PM
The report documents the discovery, the first finding of HPAIV in a cetacean in North America, from the initial response by UF's Marine Animal Rescue team to a report of a distressed dolphin in Dixie County, Florida.
phys.org/news/2024-04...
phys.org/news/2024-04...
Full article: Neutralizing activity against bovine H5N1 HPAIV (clade 2.3.4.4b) in human plasma after seasonal influenza vaccination doi.org/10.1080/2222...
Neutralizing activity against bovine H5N1 HPAIV (clade 2.3.4.4b) in human plasma after seasonal influenza vaccination
In 2024, a clade 2.3.4.4b H5N1 highly pathogenic avian influenza virus (HPAIV) emerged in dairy cattle in the United States and spread rapidly to over 1,000 herds across multiple states. At least 4...
doi.org
August 15, 2025 at 9:03 PM
Full article: Neutralizing activity against bovine H5N1 HPAIV (clade 2.3.4.4b) in human plasma after seasonal influenza vaccination doi.org/10.1080/2222...
The International Australis Expedition aimed to study the spread & impact of highly pathogenic avian influenza (HPAI) in Antarctic wildlife (doi.org/10.1038/s415...). Now, establishment of HPAI H5 as the cause of a die-off of south polar skuas is online as a preprint. www.biorxiv.org/content/10.1...
The expanding avian influenza panzootic: skua die-off in Antarctica
High pathogenicity avian influenza virus of subtype H5 (H5 HPAIV), clade 2.3.4.4b, invaded Antarctica in 2023. Here we show that H5 HPAIV caused high mortality in a breeding colony of skuas at one of ...
www.biorxiv.org
April 26, 2025 at 9:42 PM
The International Australis Expedition aimed to study the spread & impact of highly pathogenic avian influenza (HPAI) in Antarctic wildlife (doi.org/10.1038/s415...). Now, establishment of HPAI H5 as the cause of a die-off of south polar skuas is online as a preprint. www.biorxiv.org/content/10.1...
Excited to be at my first @microbiologysociety.org annual conference with the Hutchinson Lab @socialinfluenza.bsky.social! Please come and find me at poster 005 (block A) if you want to talk about biosafe methods to study HPAIV H5N1 🦠
March 31, 2025 at 4:57 PM
Excited to be at my first @microbiologysociety.org annual conference with the Hutchinson Lab @socialinfluenza.bsky.social! Please come and find me at poster 005 (block A) if you want to talk about biosafe methods to study HPAIV H5N1 🦠
In CID, Ismaila Shittu, PhD, and colleagues studied two Texas dairy farms which had suffered incursions of H5N1 highly pathogenic avian influenza virus (HPAIV) the previous month.
A One Health Investigation into H5N1 Avian Influenza Virus Epizootics on Two Dairy Farms
In early April 2024 we studied two Texas dairy farms which had suffered incursions of H5N1 highly pathogenic avian influenza virus (HPAIV) the previous month.
academic.oup.com
December 24, 2024 at 7:33 PM
In CID, Ismaila Shittu, PhD, and colleagues studied two Texas dairy farms which had suffered incursions of H5N1 highly pathogenic avian influenza virus (HPAIV) the previous month.
Friedrich Löffler Institut: Infektionen mit hochpathogenen aviären Influenzaviren (HPAIV) des Subtyps #H5N1 bei Wiederkäuern in den U.S.A. (27.03.2024)
www.fli.de/de/aktuelles... #Vogelgrippe
www.fli.de/de/aktuelles... #Vogelgrippe
Infektionen mit hochpathogenen aviären Influenzaviren (HPAIV) des Subtyps H5N1 bei Wiederkäuern in den U.S.A.
Neues Einzelansicht
www.fli.de
April 1, 2024 at 7:16 PM
Friedrich Löffler Institut: Infektionen mit hochpathogenen aviären Influenzaviren (HPAIV) des Subtyps #H5N1 bei Wiederkäuern in den U.S.A. (27.03.2024)
www.fli.de/de/aktuelles... #Vogelgrippe
www.fli.de/de/aktuelles... #Vogelgrippe
Have you seen this? www.poultrymed.com/Poultrymed/T...
Mammal-to-mammal transmission of HPAIV among marine mammals | Infectious Diseases 2025 | Infectious diseases | Poultrymed
www.poultrymed.com
March 6, 2025 at 8:37 AM
Have you seen this? www.poultrymed.com/Poultrymed/T...
Emergence of D1.1 reassortant H5N1 avian influenza viruses in North America
Hoghly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality since 2021.
www.biorxiv.org/cont...
1/2
Hoghly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality since 2021.
www.biorxiv.org/cont...
1/2
Emergence of D1.1 reassortant H5N1 avian influenza viruses in North America
Since 2021, highly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality in North American wild birds and poultry. In 2025, a new D1.1 genotype caused two human deaths and host-switched to dairy cattle. However, the evolutionary origins and dynamics of D1.1 have not been fully characterized. Here, our phylogenetic analysis of 17,516 H5N1 genome sequences uncovers how D1.1 introduced a major shift in the antigenic diversity and ecology of the H5N1 epizootic in North America. D1.1 is the first major H5N1 genotype to (a) emerge in the Pacific flyway and spread west-to-east faster than any prior genotype; (b) antigenically shift via reassortment with the North American N1 segment, displacing the previously fixed Eurasian N1; and (c) transmit to a broader range of host species than any H5N1 genotype to date, introducing mammalian adaptations.
### Competing Interest Statement
The authors have declared no competing interest.
Research Foundation - Flanders, https://ror.org/03qtxy027, G098321N, G0E1420N
European Union Horizon 2023 RIA project LEAPS, 101094685
DURABLE EU4Health project 02/2023-01/2027, 101102733
Fonds National de la Recherche Scientifique, F.4515.22
European Union Horizon 2020 project MOOD, 874850
www.biorxiv.org
December 30, 2025 at 8:07 AM
Emergence of D1.1 reassortant H5N1 avian influenza viruses in North America
Hoghly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality since 2021.
www.biorxiv.org/cont...
1/2
Hoghly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality since 2021.
www.biorxiv.org/cont...
1/2
eBird and Bird Flu Radar, in combination with global cattle density data used to evaluate risk of HPAI jumping from wild birds to cattle in Denmark w heterogeneous temporal and spatial distribution of HPAIV spillover risk
👉 arxiv.org/pdf/2504.12432
👉 arxiv.org/pdf/2504.12432
April 22, 2025 at 1:30 AM
eBird and Bird Flu Radar, in combination with global cattle density data used to evaluate risk of HPAI jumping from wild birds to cattle in Denmark w heterogeneous temporal and spatial distribution of HPAIV spillover risk
👉 arxiv.org/pdf/2504.12432
👉 arxiv.org/pdf/2504.12432
14 year AIV dataset from SE Alaska: virus prevalence 🔺 during periods of HPAIV introduction. Reassortment > novel HPAIV genotypes +1 LPAIV w a HPAIV gene segment. The proportion of Eurasian-lineage gene segments 🔺 following introduction of HPAIVs in 2022
👉 www.nature.com/articles/s44...
👉 www.nature.com/articles/s44...
July 31, 2026 at 5:17 AM
14 year AIV dataset from SE Alaska: virus prevalence 🔺 during periods of HPAIV introduction. Reassortment > novel HPAIV genotypes +1 LPAIV w a HPAIV gene segment. The proportion of Eurasian-lineage gene segments 🔺 following introduction of HPAIVs in 2022
👉 www.nature.com/articles/s44...
👉 www.nature.com/articles/s44...